公开(公告)号：KR101209889B1

公开(公告)日：2012-12-10

申请号：KR1020100045593

申请日：2010-05-14

Applicant: 한국식품연구원 ,  한국화학연구원

Inventor： 권대영 ,  황진택 ,  양혜정 ,  김성희 ,  박재호 ,  김영섭 ,  유시용 ,  연규환

IPC: A61K36/232 ,  A61K31/37 ,  A61P3/04 ,  A61P3/00

Abstract: 본발명은당귀의주성분인데쿠르신으로부터합성된유도체인데쿠시놀벤조에이트(Decursinol benzoate)를이용한비만예방용또는비만치료용조성물에관한것으로써, 보다상세하게는상기데쿠시놀벤조네이트는 AMPK(5' adenosine monophosphate-activated protein kinase)활성능을가짐으로써지방산합성을억제하는것을특징으로갖거나, PPAR-GAMMA(Peroxisome proliferator-activated receptor gamma)의발현및 전사활성을억제하는것을특징으로가질수 있다.

公开(公告)号：KR1020120061018A

公开(公告)日：2012-06-12

申请号：KR1020100109058

申请日：2010-11-04

Applicant: 한국식품연구원

Inventor： 권대영 ,  성미정 ,  황진택 ,  박재호 ,  양혜정 ,  허행전 ,  김현진 ,  김명선

IPC: A61K31/26 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10

Abstract: PURPOSE: A pharmaceutical composition and health functional food containing p-xyleneselenocyanate are provided to prevent and treat obesity and lipid-related metabolic disorders. CONSTITUTION: A pharmaceutical composition for preventing and treating obesity and lipid-related metabolic disorders contains 0.1-50 wt% of p-xylene selenocyanate as an active ingreedient. The metabolic diseases include diabetes, hyperlipidemia, fatty liver, artheriosclerosis, hypertension, cardiovascular diseases, or a combination thereof. The composition is manufactured in the form of powder, granules, tablets, capsules, suspension, emulsion, syrup, oral formulation of aerosol, external use formulation, suppository, or sterilized injection solution. A health functional food for preventing and relieving obesity and lipid-related metabolic disorders contains p-xylene selenocyanate as an active ingredient.

Abstract translation: 目的：提供含有对二甲苯硒异氰酸酯的药物组合物和保健功能食品，用于预防和治疗肥胖症和与脂质有关的代谢紊乱。 构成：用于预防和治疗肥胖症和与脂质有关的代谢紊乱的药物组合物含有0.1-50重量％的对二甲苯硒氰酸酯作为活性成分。 代谢疾病包括糖尿病，高脂血症，脂肪肝，神经硬化，高血压，心血管疾病或其组合。 组合物以粉末，颗粒，片剂，胶囊，悬浮液，乳剂，糖浆，气雾剂口服制剂，外用制剂，栓剂或灭菌注射液的形式制造。 用于预防和减轻肥胖症和与脂质有关的代谢紊乱的健康功能食品含有对二甲苯硒氰酸酯作为活性成分。

公开(公告)号：KR1020120061016A

公开(公告)日：2012-06-12

申请号：KR1020100109049

申请日：2010-11-04

Applicant: 한국식품연구원

Inventor： 권대영 ,  성미정 ,  황진택 ,  박재호 ,  양혜정 ,  허행전 ,  김현진 ,  윤석후

IPC: A61K31/26 ,  A61P3/04 ,  A61P3/00

Abstract: PURPOSE: A pharmaceutical composition containing sulforaphane is provided to suppress adipocyte differentiation and to prevent and treat obesity and metabolic diseases. CONSTITUTION: A pharmaceutical composition for preventing and treating obesity and lipid metabolic diseased contains 0.1-50 wt% of sulforaphane as an active ingredient. The sulforaphane includes R,S-sulforaphane, R-sulforaphane, or S-sulforaphane. The composition is manufactured in the form of powder, granules, tablets, capsules, suspension, emulsion, syrup, aerosol, suppository, or sterilization injection solution. A health functional food for preventing and relieving obesity and lipid metabolic diseases contains sulforaphane as an active ingredient.

Abstract translation: 目的：提供含有萝卜硫素的药物组合物，以抑制脂肪细胞分化，预防和治疗肥胖症和代谢疾病。 构成：用于预防和治疗肥胖症和脂质代谢疾病的药物组合物含有0.1-50重量％的萝卜硫素作为活性成分。 萝卜硫烷包括R，S-四氢萘烷，R-萝卜硫烷或S-萝卜硫烷。 该组合物以粉末，颗粒，片剂，胶囊，悬浮液，乳剂，糖浆，气雾剂，栓剂或灭菌注射溶液的形式制备。 用于预防和减轻肥胖和脂质代谢疾病的健康功能食品含有萝卜硫素作为活性成分。

公开(公告)号：KR1020120003779A

公开(公告)日：2012-01-11

申请号：KR1020100064564

申请日：2010-07-05

Applicant: 한국식품연구원

Inventor： 황진택 ,  권대영 ,  성미정 ,  박재호 ,  양혜정 ,  김명선 ,  김현진 ,  허행전 ,  김영섭 ,  유시용

IPC: A61K36/185 ,  A61P3/04 ,  A61P3/00

Abstract: PURPOSE: A composition containing Pittosporum heterophyllum extract for preventing or treating obesity is provided to suppress differentiation of adipocytes and to activate AMPK(5'AMP-activated protein kinase). CONSTITUTION: A composition for preventing and treating obesity contains 0.1-99.9 wt% of Pittosporum heterophyllum extract as an active ingredient. The composition is a pharmaceutical composition or food additive composition. A food composition for preventing and treating obesity contains Pittosporum heterophyllum extract as an active ingredient. The composition is manufactured in the form of a pill, powder, granule, tablet, capsule, or beverage.

Abstract translation: 目的：提供含有用于预防或治疗肥胖症的Pittosporum heterophyllum提取物的组合物，以抑制脂肪细胞的分化并激活AMPK（5'AMP激活的蛋白激酶）。 构成：用于预防和治疗肥胖症的组合物含有0.1-99.9重量％的作为活性成分的Pittosporum heterophyllum提取物。 该组合物是药物组合物或食品添加剂组合物。 用于预防和治疗肥胖症的食物组合物含有作为活性成分的孔雀虱提取物。 组合物以丸剂，粉剂，颗粒剂，片剂，胶囊剂或饮料的形式制备。