당귀의 주성분인 데쿠르신으로부터 합성된 유도체인 데쿠시놀 벤조에이트를 이용한 비만예방용 또는 비만치료용 조성물
    4.
    发明公开
    당귀의 주성분인 데쿠르신으로부터 합성된 유도체인 데쿠시놀 벤조에이트를 이용한 비만예방용 또는 비만치료용 조성물 有权
    从韩国安哥拉提取的去甲苯酚苯甲酸酯的组合物,用于预防肥胖或治疗肥胖

    公开(公告)号:KR1020110125940A

    公开(公告)日:2011-11-22

    申请号:KR1020100045593

    申请日:2010-05-14

    Abstract: PURPOSE: A composition containing derivatives synthesized from decursin for preventing or treating obesity is provided to suppress fatty acid synthesis. CONSTITUTION: A composition for preventing or treating obesity contains decursinol benzoate which is synthedized from decursin. The decursinol benzoate suppresses fatty acid synthesis by AMPK(5' adenosine monophosphate-activated protein kinase) activity. A method for synthesizing decursinol benzoate comprises: a step of performing enfleurage of dried Angelicae gigantis Radix in methanol at room temperature for seven days and filtering; a step of suspending the methanol extract in distilled water and isolating dichloromethane; and a step of freeze-drying and performing silicagel column chromatography to prepare six fraction.

    Abstract translation: 目的:提供含有由前代素合成的用于预防或治疗肥胖症的衍生物的组合物以抑制脂肪酸合成。 构成:用于预防或治疗肥胖症的组合物含有由前胡素合成的去甲基苯甲酸酯。 苯酚去甲酚抑制AMPK(5'腺苷单磷酸激活蛋白激酶)活性的脂肪酸合成。 合成前酚醇苯甲酸酯的方法包括:在室温下在甲醇中进行七天的过滤干燥的当归香草, 将甲醇提取物悬浮在蒸馏水中并分离二氯甲烷的步骤; 和冷冻干燥并进行硅胶柱色谱以制备6份。

    에스트로겐 활성이 우수한 보골지 추출물 또는 상기 보골지추출물로부터 분리한 활성성분을 포함하는 조성물
    6.
    发明公开
    에스트로겐 활성이 우수한 보골지 추출물 또는 상기 보골지추출물로부터 분리한 활성성분을 포함하는 조성물 有权
    PSORALEA COYLIFLIA与其高纯度活性或其包含功能组分的提取物的提取物

    公开(公告)号:KR1020090036803A

    公开(公告)日:2009-04-15

    申请号:KR1020070102066

    申请日:2007-10-10

    CPC classification number: A61K36/487 A23V2200/306 A61K2236/33

    Abstract: Psoralea coyliflia extracts with high estrogenic activity or a composition containing active components separated from the Psoralea corylifolia extracts are provided to replace a hormone replacement therapy which administers estrogen by using a natural product. A method for separating active components from Psoralea corylifolia extracts comprises the steps of: (i) extracting Psoralea corylifolia alcohol solvent extract with dichloromethane; (ii) performing silica gel column chromatography that makes the dichloromethane/methanol solution in Psoralea corylifolia dichloromethane extracts mobile to obtain the first fraction or the eleventh fraction; and (iii) performing silica gel column chromatography that makes normal hexane/ethylacetate in the third fraction among 11 fractions mobile to obtain 10 fractions from 3-1 to 3-10, and vacuum concentrating 3-2 fraction to obtain bakuchiol.

    Abstract translation: 提供具有高雌激素活性的补骨脂提取物或含有从补骨脂提取物中分离出的活性成分的组合物以代替通过使用天然产物来施用雌激素的激素替代疗法。 从茯苓提取物中分离活性成分的方法包括以下步骤:(i)用二氯甲烷萃取茯苓醇溶剂提取物; (ⅱ)进行硅胶柱层析,使二氯甲烷/甲醇溶液中的二氯甲烷/甲醇溶液移动,得到第一级分或第十一级分; 和(iii)进行硅胶柱色谱法,使第11馏分中的第1馏分中的正级己烷/乙酸乙酯成为11份,得到10份3-1〜3-10馏分,真空浓缩3〜3份,得到苯酚酚。

    삼백초 추출물 또는 이로부터 분리된 활성성분을 포함하는면역억제용 조성물
    8.
    发明公开
    삼백초 추출물 또는 이로부터 분리된 활성성분을 포함하는면역억제용 조성물 失效
    包含SAURURUS CHINENSIS或活性化合物的提取物的免疫组织化学物质分离

    公开(公告)号:KR1020070068689A

    公开(公告)日:2007-07-02

    申请号:KR1020050130601

    申请日:2005-12-27

    Abstract: A composition for immunosuppression comprising the extract of Saururus chinensis or active compounds isolated therefrom is provided to inhibit abnormal proliferation of B cell and T cell, so that the composition is useful for prevention and treatment of diseases caused by hypersensitive immune responses. The composition for immunosuppression comprises the extract of Saururus chinensis or an active compound isolated from the Saururus chinensis extract selected from (-)-saucerneol, saucerneol C, manassantin A, manassantin B and a mixture thereof as effective ingredient, wherein the Saururus chinensis extract is prepared by using an organic solvent selected from methanol, methanol solution, ethanol, ethanol solution, butanol, dichloromethane, ethylacetate and a mixture thereof. The composition is a pharmaceutical or health food composition. The pharmaceutical composition prevents or treats diseases caused by hypersensitive immune responses including organ transplant rejection, autoimmune disease including lupous erythematosus and rheumatoid arthritis, and allergy disease including rhinitis, asthma and atopic dermatitis, and the health food composition is formulated as drink.

    Abstract translation: 提供了包含中华黄牛提取物或从其分离的活性化合物的免疫抑制组合物以抑制B细胞和T细胞的异常增殖,使得该组合物可用于预防和治疗由过敏免疫应答引起的疾病。 用于免疫抑制的组合物包含中华黄牛提取物或从中选出的( - ) - 沙美拉诺,沙门氏菌素C,马那敏蛋白A,他曼那丁B及其混合物中选择的中华黄瓜提取物作为有效成分分离的活性化合物,其中中华黄瓜提取物为 通过使用选自甲醇,甲醇溶液,乙醇,乙醇溶液,丁醇,二氯甲烷,乙酸乙酯及其混合物的有机溶剂制备。 该组合物是药物或保健食品组合物。 药物组合物预防或治疗由过敏免疫应答引起的疾病,包括器官移植排斥反应,自身免疫性疾病,包括红斑狼疮和类风湿性关节炎,以及过敏疾病,包括鼻炎,哮喘和特应性皮炎,健康食品组合物配制成饮料。

    백굴채 추출물을 유효성분으로 함유하는 비만예방 및 치료용 조성물
    9.
    发明公开
    백굴채 추출물을 유효성분으로 함유하는 비만예방 및 치료용 조성물 无效
    预防和治疗包含CHARIDONIUM MAJUS VAR ASIATICUM萃取物的成分的组合物

    公开(公告)号:KR1020120003778A

    公开(公告)日:2012-01-11

    申请号:KR1020100064563

    申请日:2010-07-05

    CPC classification number: A61K36/66 A61K2236/33 Y10S514/909

    Abstract: PURPOSE: A composition containing Chelidonium majus var asiaticum extract is provided to activate AMPK(5'AMP-activated protein kinase) and to ensure antiobesity. CONSTITUTION: A composition for preventing and treating obesity contains 0.1-99.9 wt% of Chelidonium majus var asiaticum extract as an active ingredient. The composition is a pharmaceutical composition or food additive composition. The food composition for preventing and treating obesity contains the extract as an active ingredient. The extract is a hot water extract or ethanol extract. The composition is manufactured in the form of beverage, gum, tea, vitamin complex, pill, powder, granule, tablet, or capsule.

    Abstract translation: 目的:提供含有Chelidonium majus var asiaticum提取物的组合物以激活AMPK(5'AMP-活化的蛋白激酶)并确保抗肥胖。 构成:用于预防和治疗肥胖症的组合物含有0.1-99.9wt%的Chelidonium majus var asiaticum提取物作为活性成分。 该组合物是药物组合物或食品添加剂组合物。 用于预防和治疗肥胖症的食物组合物含有提取物作为活性成分。 提取物是热水提取物或乙醇提取物。 该组合物以饮料,口香糖,茶叶,维生素复合物,丸剂,粉末,颗粒,片剂或胶囊的形式制成。

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