대추 추출물을 유효성분으로 함유하는 허혈성 뇌혈관질환의 예방 및 치료용 조성물
    1.
    发明授权
    대추 추출물을 유효성분으로 함유하는 허혈성 뇌혈관질환의 예방 및 치료용 조성물 有权
    组成包括ZIZIPHUS JUJUBA MILL的提取物。 用于预防和治疗ISCHEMIA损伤疾病的多种螺旋体

    公开(公告)号:KR100757207B1

    公开(公告)日:2007-09-10

    申请号:KR1020060088897

    申请日:2006-09-14

    CPC classification number: A61K36/725 A23V2200/322 A61K2236/331 A61K2236/333

    Abstract: A composition for prevention and treatment of ischemia cerebrovascular disease comprising the extract of Ziziphus jujuba MILL.(jujube) is provided to prevent damage of neuronal cells of hippocampus tissue CA1 region and inhibit apoptosis of neuronal cells without side effects. A composition for prevention and treatment of ischemia cerebrovascular disease comprises the extract of Ziziphus jujuba MILL. which is prepared by extracting with water, methanol, ethanol, butanol or a mixed solvent thereof, wherein the ischemia cerebrovascular disease is cerebral infarction, stroke, cerebral hemorrhage or subarachnoidal hemorrhage, and the composition is a pharmaceutical or health food composition formulated as powder, granule, tablet, capsule or drink.

    Abstract translation: 提供一种预防和治疗缺血性脑血管病的组合物,其包含枣子提取物(枣),以防止海马组织CA1区域的神经元细胞的损伤并抑制神经元细胞的凋亡而没有副作用。 一种用于预防和治疗缺血性脑血管病的组合物,其特征在于含有枣枣的提取物。 其是通过用水,甲醇,乙醇,丁醇或其混合溶剂萃取而制备的,其中所述缺血性脑血管病是脑梗塞,中风,脑出血或蛛网膜下腔出血,并且该组合物是配制成粉末的药物或保健食品组合物, 颗粒,片剂,胶囊或饮料。

    복분자 추출물 및 이를 유효성분으로 함유하는 신경세포생성 촉진용 약학적 조성물
    3.
    发明公开
    복분자 추출물 및 이를 유효성분으로 함유하는 신경세포생성 촉진용 약학적 조성물 有权
    RUBUS COREANUS MIQ的提取物。 和包含其促进神经发生的药物组合物

    公开(公告)号:KR1020090082684A

    公开(公告)日:2009-07-31

    申请号:KR1020080008587

    申请日:2008-01-28

    CPC classification number: A61K36/73 A23V2200/322 A61K2236/331 A61K2236/333

    Abstract: An extract of Rubus Coreanus, and a pharmaceutical composition containing it are provided to promote the generation of the nerve cell by improving the differentiation reduction of the stem cell into the nerve cell in case of aging. An extract of Rubus Coreanus is prepared by extracting Rubus Coreanus with a solvent selected from the group consisting of water, low molecular weight alcohol of the carbon number 1 ~ 4 and their mixture. Preferably the extraction is carried out by cold water extraction, hot water extraction, ultrasonic wave extraction or reflux cooling extraction at a temperature of 20-150 °C for 1 hours to 10 days.

    Abstract translation: 提供了Rubus Coreanus的提取物和含有它的药物组合物,以通过在老化的情况下改善干细胞进入神经细胞的分化减少来促进神经细胞的产生。 通过用选自碳数1〜4的水,低分子量醇和它们的混合物的溶剂萃取Rubus Coreanus来制备Rubus Coreanus的提取物。 优选通过冷水萃取,热水萃取,超声波萃取或回流冷却提取在20-150℃的温度下进行萃取1小时至10天。

    흰색 감국 추출물을 포함하는 뇌허혈 질환 예방 또는 개선용 조성물
    4.
    发明公开
    흰색 감국 추출물을 포함하는 뇌허혈 질환 예방 또는 개선용 조성물 有权
    用于预防或改善含有CHRYSANTHEMUM INDICUM VAR的提取物的脑缺血病的组合物。 ALBESCENS

    公开(公告)号:KR1020090076195A

    公开(公告)日:2009-07-13

    申请号:KR1020080001996

    申请日:2008-01-08

    Abstract: A composition for preventing or treating brain ischemia diseases, which contains white Chrysanthemum indicum Var. albescens as an active ingredient is provided to prevent nerve injury of CA1 area of brain hippocampus. A composition for preventing and treating brain ischemia diseases comprises 0.001-99.99 weight% of Chrysanthemum indicum var. albescens extract as an active ingredient. The brain ischemia diseases are cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage and white matter. The Chrysanthemum indicum var. albescens extract is isolated with 30-80% of alcohol solution of 1-5 carbon atoms. The composition further comprises a carrier, excipient, and diluents. The composition is used in a form of powder, granule, tablet, suspension, emulsion or syrup.

    Abstract translation: 一种预防或治疗脑缺血疾病的组合物,其含有白菊花Var。 提供albescens作为活性成分,以防止脑海马CA1区域的神经损伤。 用于预防和治疗脑缺血疾病的组合物包含菊花变种的0.001-99.99重量% 白花提取物作为活性成分。 脑缺血病是脑梗塞,脑出血,蛛网膜下腔出血和白质。 菊花变种 用30-80%的1-5个碳原子的醇溶液分离白鼬提取物。 组合物还包含载体,赋形剂和稀释剂。 该组合物以粉末,颗粒,片剂,悬浮液,乳剂或糖浆的形式使用。

    삼지구엽초 추출물을 포함하는 허혈성 뇌혈관질환 예방또는 개선용 조성물
    6.
    发明公开
    삼지구엽초 추출물을 포함하는 허혈성 뇌혈관질환 예방또는 개선용 조성물 有权
    用于预防或改善压制猕猴桃提取物的异味损伤的组合物

    公开(公告)号:KR1020070092497A

    公开(公告)日:2007-09-13

    申请号:KR1020060022721

    申请日:2006-03-10

    Abstract: A composition comprising an extract of Epimedium Koreanum harmless to human body is provided to prevent neuronal damage effectively at a hippocampus CA1 area, thereby capable of preventing or improving ischemic damage disease such as vascular dementia, Alzheimer's disease and stroke. A composition for preventing and treating ischemic damage disease comprises 0.001-99.99 wt.% of an extract of Epimedium Koreanum prepared by using at least one solvent selected from the group consisting of water, C1-4 alcohol, hexane, ethyl acetate and dichloromethane as an effective ingredient.

    Abstract translation: 提供包含对人体无害的淫羊藿提取物的组合物以在海马CA1区域有效地防止神经元损伤,由此能够预防或改善缺血性损伤疾病如血管性痴呆,阿尔茨海默病和中风。 用于预防和治疗缺血性损伤疾病的组合物包含通过使用至少一种选自水,C 1-4醇,己烷,乙酸乙酯和二氯甲烷的溶剂作为制备的淫羊藿提取物的0.001-99.99重量% 有效成分。

    에스시탈로프람을 포함하는 허혈성 뇌질환 예방 또는 개선용 약학조성물
    8.
    发明公开
    에스시탈로프람을 포함하는 허혈성 뇌질환 예방 또는 개선용 약학조성물 无效
    用于预防或改善含有ESCITALOPRAM的异常脑疾病的药理学组合物

    公开(公告)号:KR1020100054452A

    公开(公告)日:2010-05-25

    申请号:KR1020080113389

    申请日:2008-11-14

    Abstract: PURPOSE: A pharmaceutical composition containing escitalopram is provided to prevent neural cell damage in a CA1 area and to prevent or treat ischemic brain diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating ischemic a brain disease contains escitalopram. Ischemic brain disease is thrombosis, embolism, transient ischemic attack, cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage, white matter dyslipidemia, or lacune. The administering of escitalopram prevents or treats ischemic brain diseases. A pharmaceutical composition for preventing or treating brain disease contains escitalopram and a pharmaceologically acceptable carrier or excipient. The pharmaceutically acceptable carrier or excipient is water, dextrin, or a saline solution. The composition is used in the form of plasters, granules, lotions, powders, syrups, liquids and solutions, aerosols, ointments, fluid extract, emulsion, suspensions, infusions, tablets, injections, capsules, or pills.

    Abstract translation: 目的:提供含有依他普仑的药物组合物,以防止CA1区域的神经细胞损伤,并预防或治疗缺血性脑病。 构成:用于预防或治疗缺血性脑病的药物组合物含有依他普仑。 缺血性脑病是血栓形成,栓塞,短暂性脑缺血发作,脑梗塞,脑出血,蛛网膜下腔出血,白质血脂异常,或泪液。 依他普仑的给药预防或治疗缺血性脑病。 用于预防或治疗脑疾病的药物组合物含有依他普仑和药物学上可接受的载体或赋形剂。 药学上可接受的载体或赋形剂是水,糊精或盐水溶液。 组合物以膏药,颗粒剂,洗剂,粉剂,糖浆,液体和溶液,气溶胶,软膏,流体萃取物,乳液,悬浮液,输液,片剂,注射剂,胶囊或丸剂的形式使用。

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