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公开(公告)号：KR1020040063878A
公开(公告)日：2004-07-14
申请号：KR1020040048061
申请日：2004-06-25
Applicant: (주)씨앤팜
CPC classification number: A61K8/492 , A61K8/02 , A61K8/25 , A61K8/26 , A61K8/27 , A61K8/365 , A61K8/368 , A61K8/498 , A61K8/671 , A61K8/678 , A61K2800/56 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , Y10T428/2982 , Y10T428/2991 , Y10T428/2993 , Y10T428/2995 , Y10T428/2998
Abstract: PURPOSE: Provided is a material for cosmetics which involves excellent stability, low toxicity, low stimulation, sustained release and high diffusion, and is made in economic and effective manners. CONSTITUTION: The cosmetic material is a hybrid material of vitamin C and lamellar metallic hydroxides. A method of manufacturing the hybrid material comprises the steps of: reacting the starting material in a basic solution to make lamellar metallic hydroxide salts; and diffusing the lamellar metallic hydroxide salts in a solvent of water, or a mixed solvent, and dissolving the vitamin C, followed by ion exchange reacting it.
Abstract translation: 目的：提供化妆品的优异稳定性，低毒性，低刺激性，持续释放和高扩散性，并以经济有效的方式制备。 构成：化妆品是维生素C和层状金属氢氧化物的混合材料。 制造混合材料的方法包括以下步骤：使起始材料在碱性溶液中反应制成片状金属氢氧化物盐; 并将层状金属氢氧化物盐扩散到水或混合溶剂的溶剂中，并溶解维生素C，然后进行离子交换反应。
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公开(公告)号：KR1020030014182A
公开(公告)日：2003-02-15
申请号：KR1020020047318
申请日：2002-08-10
Applicant: (주)씨앤팜
Abstract: PURPOSE: A process of preparing a hybrid material containing 3-benzoyl-α -methylbenzene acetic acid, 4-biphenyl acetic acid, minocycline, etc. is provided. Whereby, the new hybrid material is useful in stabilization and delivery of specified drugs, low in adverse effects and excellent in stability and can be used in the form of an ointment, patch, oral administration, injection or the like. CONSTITUTION: The hybrid material is prepared by coprecipitation or ion exchange reaction of: a drug selected from the group consisting of 3-benzoyl-α-methylbenzene acetic acid, 4-biphenyl acetic acid and minocycline; and a layered inorganic material selected from the group consisting of layered silicate, layered aluminosilicate, layered phosphate and layered metal oxide.
Abstract translation: 目的：提供一种制备含3-苯甲酰基-α-甲基苯乙酸，4-联苯乙酸，米诺环素等的杂化材料的方法。 因此，新的混合材料可用于稳定和递送特定药物，不良反应低，稳定性优异，可以以软膏，贴剂，口服给药，注射等形式使用。 构成：杂化材料通过共沉淀或离子交换反应制备：选自3-苯甲酰基-α-甲基苯乙酸，4-联苯乙酸和米诺环素的药物; 以及选自层状硅酸盐，层状硅铝酸盐，层状磷酸盐和层状金属氧化物的层状无机材料。
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Patent Agency Ranking
公开(公告)号：KR100841700B1
公开(公告)日：2008-06-26
申请号：KR1020040048061
申请日：2004-06-25
Applicant: (주)씨앤팜
CPC classification number: A61K8/492 , A61K8/02 , A61K8/25 , A61K8/26 , A61K8/27 , A61K8/365 , A61K8/368 , A61K8/498 , A61K8/671 , A61K8/678 , A61K2800/56 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , Y10T428/2982 , Y10T428/2991 , Y10T428/2993 , Y10T428/2995 , Y10T428/2998
Abstract: 본 발명은 안정성, 저독성, 저자극성, 서방성, 분산성이 우수한, 화장품 원료용 활성 성분과 층상 금속 수산화물의 혼성 물질을 제공한다.
또한, 본 발명은 화장품 원료용 활성 성분의 특성에 따라 공침법, 이온교환법, 또는 흡착법을 이용한 상기 혼성 물질의 제조 방법을 제공한다.
또한, 본 발명은 상기 혼성 물질을 포함하는 화장품을 제공한다.
화장품, 층상 금속 수산화물, 혼성 물질Abstract translation: 本发明提供由化妆品原料的活性成分和层状金属氢氧化物构成的混合材料，显示出良好的稳定性，低毒性，低刺激性，良好的缓释性和良好的分散性。 本发明提供一种使用共沉淀法，离子交换法或吸附法制备杂化材料的方法，这取决于化妆品原料的活性成分的性质。 该方法还可以包括在制备混合材料之后涂覆混合材料的表面的步骤。 本发明提供了包含上述混合材料的宇宙学。
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公开(公告)号：KR1020030015843A
公开(公告)日：2003-02-25
申请号：KR1020020044143
申请日：2002-07-26
Applicant: (주)씨앤팜
CPC classification number: A61K8/492 , A61K8/02 , A61K8/25 , A61K8/26 , A61K8/27 , A61K8/365 , A61K8/368 , A61K8/498 , A61K8/671 , A61K8/678 , A61K2800/56 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , Y10T428/2982 , Y10T428/2991 , Y10T428/2993 , Y10T428/2995 , Y10T428/2998
Abstract: PURPOSE: A process for preparing as cosmetic material as a hybrid matter comprising a cosmetic active component and layered metal hydroxide is provided. The hybrid matter has excellent stability, low toxicity, low irritation, sustained release property and dispersibility, therefore, the cosmetic containing the same has also characteristics such as skin whitening, comedolytic activity, wrinkle resistance, brown spot removal, skin moisturizing, harmful UV shielding, waste matter removal, etc. CONSTITUTION: The hybrid matter comprises: a cosmetic active component selected from vitamin A, vitamin C, vitamin E, vitamin derivatives, lactic acid, citric acid, kojic acid, indole-3-acetic acid and salicylic acid; and a layered metal hydroxide as a metal double-layered hydroxide. The layered metal hydroxide as starting material, reacts in a basic solution to produce a layered metal hydroxide salt. The layered metal hydroxide salt is dispersed in a water solvent or a mixed solvent, mixed with a cosmetic active component and then reacts. The surface of the hybrid matter is coated with at least one selected from the group consisting of polyvinyl alcohol, polyethylene glycol, cellulose, polymethylmethacrylate and silane.
Abstract translation: 目的：提供一种作为化妆品材料制备的包含化妆品活性成分和层状金属氢氧化物的混合物的方法。 混合物具有优异的稳定性，低毒性，低刺激性，缓释性和分散性，因此含有其的化妆品也具有皮肤美白，肌肤活性，抗皱，褐斑去除，皮肤保湿，有害紫外线屏蔽等特征 废物去除等构成：混合物包括：选自维生素A，维生素C，维生素E，维生素衍生物，乳酸，柠檬酸，曲酸，吲哚-3-乙酸和水杨酸的化妆品活性成分 ; 和作为金属双层氢氧化物的层状金属氢氧化物。 层状金属氢氧化物作为原料，在碱性溶液中反应，生成层状金属氢氧化物盐。 将层状金属氢氧化物盐分散在水溶剂或混合溶剂中，与化妆品活性成分混合后进行反应。 混合物的表面涂覆有选自聚乙烯醇，聚乙二醇，纤维素，聚甲基丙烯酸甲酯和硅烷中的至少一种。
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公开(公告)号：KR100523525B1
公开(公告)日：2005-10-25
申请号：KR1020020047318
申请日：2002-08-10
Applicant: (주)씨앤팜
Abstract: 본 발명은 안정성과 서방성이 우수하고 부작용이 적은 약물 전달 시스템으로서 3-벤조일-α-메틸벤젠아세트산, 4-비페닐아세트산, 및 미노시클린으로 이루어진 군으로부터 선택된 약물과 층상 무기 물질의 혼성 물질을 제공한다.
또한, 본 발명은 약물의 특성에 따라 공침법 및 이온교환법을 이용한 상기 혼성 물질의 제조 방법을 제공한다. 혼성 물질의 제조 후 그 표면을 코팅하는 단계를 더 포함할 수 있다.
또한, 본 발명은 상기 혼성 물질을 포함하는 약학 조성물을 제공한다.-
公开(公告)号：KR100439299B1
公开(公告)日：2004-07-07
申请号：KR1020020044143
申请日：2002-07-26
Applicant: (주)씨앤팜
CPC classification number: A61K8/492 , A61K8/02 , A61K8/25 , A61K8/26 , A61K8/27 , A61K8/365 , A61K8/368 , A61K8/498 , A61K8/671 , A61K8/678 , A61K2800/56 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , Y10T428/2982 , Y10T428/2991 , Y10T428/2993 , Y10T428/2995 , Y10T428/2998
Abstract: 본 발명은 안정성, 저독성, 저자극성, 서방성, 분산성이 우수한, 화장품 원료용 활성 성분과 층상 금속 수산화물의 혼성 물질을 제공한다.
또한, 본 발명은 화장품 원료용 활성 성분의 특성에 따라 공침법, 이온교환법, 또는 흡착법을 이용한 상기 혼성 물질의 제조 방법을 제공한다. 혼성 물질의 제조 후 그 표면을 코팅하는 단계를 더 포함할 수 있다.
또한, 본 발명은 상기 혼성 물질을 포함하는 화장품을 제공한다.Abstract translation: 本发明提供由化妆品原料的活性成分和层状金属氢氧化物构成的混合材料，显示出良好的稳定性，低毒性，低刺激性，良好的缓释性和良好的分散性。 本发明提供一种使用共沉淀法，离子交换法或吸附法制备杂化材料的方法，这取决于化妆品原料的活性成分的性质。 该方法还可以包括在制备混合材料之后涂覆混合材料的表面的步骤。 本发明提供了包含上述混合材料的宇宙学。
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公开(公告)号：KR1020040010306A
公开(公告)日：2004-01-31
申请号：KR1020030050119
申请日：2003-07-22
Applicant: (주)씨앤팜
IPC: A61K47/02
CPC classification number: A61K31/403 , A61K9/143 , A61K31/496 , A61K38/13
Abstract: PURPOSE: Provided are a hybrid of itraconazole, cyclosporine or carvedilol with a layered silicate and a process for preparing the same, thereby releasing drugs from the layered silicate and maximizing their bioavailability in the living body. CONSTITUTION: A hybrid of itraconazole, cyclosporine or carvedilol with a layered silicate is characterized in that itraconazole, cyclosporine or carvedilol is inserted between silicate layers or absorbed to the surface of the layered silicate. It is manufactured by the steps of: preparing a solution containing layered silicate by dispersing the layered silicate in a water soluble solvent; preparing a drugs-containing solution by dissolving drugs in an organic solvent; and mixing the above solutions together to insert drugs between silicate layers or absorb them to the surface to the surface of the layered silicate.
Abstract translation: 目的：提供伊曲康唑，环孢菌素或卡维地洛与层状硅酸盐的混合物及其制备方法，从而从层状硅酸盐释放药物并使其在生物体中的生物利用度最大化。 构成：伊曲康唑，环孢菌素或卡维地洛与层状硅酸盐的混合物的特征在于，伊曲康唑，环孢菌素或卡维地洛插入硅酸盐层之间或吸收到层状硅酸盐的表面。 通过以下步骤制造：通过将层状硅酸盐分散在水溶性溶剂中来制备含有层状硅酸盐的溶液; 通过将药物溶解在有机溶剂中制备药物溶液; 并将上述溶液混合在一起，将药物插入硅酸盐层之间或将其吸收到层状硅酸盐表面。
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