-
1.发明公开세포성 면역 억제를 위한 인간 ＦａｓＬ 단백질을 발현하는 형질전환 돼지 클론 체세포주 및 이를 이용한 형질전환 복제돼지 有权表达人体蛋白质以抑制细胞免疫的转基因克隆细胞系和使用其的转基因蛋白
公开(公告)号：KR1020110093132A
公开(公告)日：2011-08-18
申请号：KR1020100012983
申请日：2010-02-11
Applicant: (주)엠젠
IPC: C12N5/10 , C12N15/85 , C12N15/12 , A01K67/027
Abstract: PURPOSE: A transgenic porcine clonal somatic cell line which expresses human FasL gene in a tissue and cells is provided to reduce cytotoxicity and to minimize immune rejection. CONSTITUTION: A transgenic porcine clonal cell line contains human FasL gene expression vector and is deposited in the number KCLRF-BP-00194. A method for preparing the somatic cell line comprises: a step of isolating somatic cells from porcine fetus; a step of preparing hFasL gene expression vector and introducing to the somatic cells; and a step of selecting expression vector-introduced somatic cells and culturing.
Abstract translation: 目的：提供在组织和细胞中表达人FasL基因的转基因猪克隆体细胞系，以减少细胞毒性并使免疫排斥最小化。 构成：转基因猪克隆细胞系含有人FasL基因表达载体，并以KCLRF-BP-00194编号。 制备体细胞系的方法包括：从猪胎儿中分离体细胞的步骤; 制备hFasL基因表达载体并引入体细胞的步骤; 选择表达载体介导的体细胞和培养的步骤。
-
2.发明授权세포성 면역 억제를 위한 인간 ＦａｓＬ 단백질을 발현하는 형질전환 돼지 클론 체세포주 및 이를 이용한 형질전환 복제돼지 有权表达人FasL蛋白以抑制细胞免疫的转基因猪克隆体细胞系和使用其的转基因克隆猪
公开(公告)号：KR101147409B1
公开(公告)日：2012-05-22
申请号：KR1020100012983
申请日：2010-02-11
Applicant: (주)엠젠
IPC: C12N5/10 , C12N15/85 , C12N15/12 , A01K67/027
Abstract: PURPOSE: A transgenic porcine clonal somatic cell line which expresses human FasL gene in a tissue and cells is provided to reduce cytotoxicity and to minimize immune rejection. CONSTITUTION: A transgenic porcine clonal cell line contains human FasL gene expression vector and is deposited in the number KCLRF-BP-00194. A method for preparing the somatic cell line comprises: a step of isolating somatic cells from porcine fetus; a step of preparing hFasL gene expression vector and introducing to the somatic cells; and a step of selecting expression vector-introduced somatic cells and culturing.
-
Search Results
2
records
(took 0.017 seconds)
