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公开(公告)号：WO2020171467A1
公开(公告)日：2020-08-27
申请号：PCT/KR2020/001956
申请日：2020-02-12
Applicant: 고려대학교 산학협력단
IPC: C23C16/455 , C23C16/448
Abstract: 본 발명의 전구체 소스 공급을 위한 금속블록 결합형 히터 어셈블리를 포함하는 증착 장치는 기판을 지지하고 증착공정에 필요한 공간을 제공하는 반응챔버; 전구체 소스를 저장하는 전구체 저장부; 상기 반응챔버에 기화된 전구체 소스를 공급하는 가스 라인부; 및 상기 전구체 저장부 및 상기 가스 라인부를 내측에 수용하여 결합되는 금속블록 및 상기 금속블록을 가열하는 히팅 재킷이 구비되는 히터 어셈블리부를 포함한다.
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公开(公告)号：KR1020090056868A
公开(公告)日：2009-06-03
申请号：KR1020080119056
申请日：2008-11-27
Applicant: 고려대학교 산학협력단
CPC classification number: B82Y5/00 , G01N33/54333 , G01N33/587 , Y10T428/2982
Abstract: A nanoparticle for peptide separation and a preparation method thereof are provided to rapidly and selectively separate desired peptide through a simple process owing to magnetic nanoparticles of which the surface is coupled with a first functional group which selectively reacts to a certain peptide. A nanoparticle for peptide separation has the magnetic surface which is coupled with a first functional group having thiol selectivity. The nanoparticle for peptide separation selectively couples with the peptide including cysteine. The first functional group includes 2-pyridyl disulfide residual group. The magnetic nanoparticle is coated with a silica layer. The first functional group is bonded with the silica layer. The surface of the nanoparticle additionally contains a second functional group which prevents the coherence of the nanoparticles.
Abstract translation: 提供了用于肽分离的纳米颗粒及其制备方法，通过简单的方法快速且有选择地分离所需的肽，因为磁性纳米颗粒与表面与选择性地与特定肽反应的第一官能团偶联。 用于肽分离的纳米颗粒具有与具有硫醇选择性的第一官能团偶联的磁性表面。 用于肽分离的纳米颗粒选择性地与包括半胱氨酸的肽结合。 第一官能团包括2-吡啶基二硫化物残基。 磁性纳米颗粒涂覆有二氧化硅层。 第一官能团与二氧化硅层结合。 纳米颗粒的表面还含有防止纳米颗粒的相干性的第二官能团。
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Patent Agency Ranking
公开(公告)号：KR101575246B1
公开(公告)日：2015-12-21
申请号：KR1020140177740
申请日：2014-12-10
Applicant: 고려대학교 산학협력단
Abstract: 본발명은 SQLite 데이터베이스파일내 손상된레코드의복원방법에관한것으로서, 보다바람직하게는 DB파일판단부가외부로부터데이터를입력받아, 입력데이터가 SQLite 데이터베이스파일인지여부를판단하는단계; 손상여부판단부가상기입력데이터가 SQLite 데이터베이스파일인경우, 상기입력데이터에대한손상여부를판단하는단계; 스캔부가상기입력데이터가손상된경우, 상기입력데이터를바이트스캔하여상기데이터베이스파일내 페이지의시작지점과페이지의크기를탐색하는단계; 스키마정보획득부가탐색된페이지의시작지점과크기에기초하여정상레코드에사용되는스키마정보를획득하는단계; 및레코드복원부가획득한스키마정보에기초하여손상된레코드를복원하는단계;를포함한다. 이러한구성에의해, 본발명의 SQLite 데이터베이스파일내 손상된레코드의복원방법은 SQLite 데이터베이스의파일구조인 B-트리를따라순회하며획득한스키마정보를이용하여손상된레코드를복원함으로써, 특정응용프로그램이나파일시스템에종속되지않으며적은오탐률로모든경우의 SQLite 데이터베이스에대하여범용적으로사용할수 있는효과가있다.
Abstract translation: 本发明涉及一种在SQLite数据库文件中恢复损坏记录的方法，更优选地包括：DB文件确定单元从外部接收数据并确定输入数据是否为SQLite数据库文件的步骤; 如果所述输入数据是所述SQLite数据库，则确定所述输入数据是否已被损坏的损伤确定单元的步骤; 扫描单元的步骤，用于扫描输入数据的字节，并且如果输入数据已被损坏，则检测数据库文件中的起始点和页面的大小; 基于搜索页面的开始点和大小，获取用于正常记录的模式信息的模式信息获取单元的步骤; 以及用于根据模式信息恢复损坏的记录的记录恢复单元的步骤。 根据本发明的SQLite数据库文件中恢复损坏记录的方法，通过使用作为SQLite数据库的文件结构的B树移动获得的模式信息来恢复损坏的记录。 因此，在所有情况下，该方法可以广泛用于SQLite数据库，而不考虑某个应用程序或文件系统的错误检测率较小。
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公开(公告)号：KR101077966B1
公开(公告)日：2011-10-31
申请号：KR1020080119056
申请日：2008-11-27
Applicant: 고려대학교 산학협력단
CPC classification number: B82Y5/00 , G01N33/54333 , G01N33/587 , Y10T428/2982
Abstract: 본발명은펩티드분리용나노입자와제조방법및 이를이용한펩티드분리방법에관한것으로서, 보다상세하게는자성나노입자의표면에티올(thiol) 선택성을갖는제1기능기가결합되어, 시스테인을포함하는펩티드와선택적으로결합하는펩티드분리용나노입자를이용하여특정펩티드를분리하는방법에관한것이다. 본발명에따르면특정펩티드를매우선택적으로간단하고신속하게분리할수 있어, 암과같은질병치료연구에유용하게사용될수 있다.
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公开(公告)号：KR1020110085268A
公开(公告)日：2011-07-27
申请号：KR1020100004950
申请日：2010-01-19
Applicant: 고려대학교 산학협력단
Abstract: PURPOSE: A liquid chromatography apparatus is provided to allow samples to be back flushed without the addition of a valve or a pump by changing the flow of a solvent using a solvent separating part. CONSTITUTION: A liquid chromatography apparatus includes a sample introducing valve(100). The sample introducing valve is composed of a sample injecting port(101), a sample discharging port(102), a first sample storing loop connecting port(103), a second sample storing loop connecting port(105), and a solvent discharging port(106). A trap valve(200) is further included in the apparatus and is composed of a solid phase extracting port connecting port(201), a reversed phase chromatography column connecting port(202), a first solvent injecting port(203), a second solvent injecting port(204), a sample moving loop connecting port(205), and a solvent discharging port(206). The trap valve is in connection with a solid phase extracting column(210) and a reversed phase liquid chromatography column(220). A solvent separating part is further included in the apparatus and separates the flow of the solvent to the first solvent injecting port and the second solvent injecting port.
Abstract translation: 目的：提供液相色谱装置，以便通过使用溶剂分离部分改变溶剂的流动来不使添加阀或泵来反冲洗样品。 构成：液相色谱装置包括样品引入阀（100）。 样品引入阀由样品注入口（101），样品排出口（102），第一样品存储回路连接口（103），第二样品存储回路连接口（105）和溶剂排出口 （106）。 收集阀（200）还包括在设备中，由固相萃取口连接口（201），反相色谱柱连接口（202），第一溶剂注入口（203），第二溶剂 注入口（204），样品移动环连接口（205）和溶剂排出口（206）。 捕集阀与固相萃取塔（210）和反相液相色谱柱（220）相连。 该装置还包括溶剂分离部分，并将溶剂流分离到第一溶剂注入口和第二溶剂注入口。
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公开(公告)号：KR101078372B1
公开(公告)日：2011-10-31
申请号：KR1020100004950
申请日：2010-01-19
Applicant: 고려대학교 산학협력단
Abstract: 본발명은액체크로마토그래피장치에관한것으로서, 분석대상이되는시료가유입되며, 시료유입포트, 시료방출포트, 시료저장루프에의해서로연결된제1 시료저장루프연결포트및 제2 시료저장루프연결포트, 용매유입포트, 및용매유출포트를포함하는시료유입밸브; 고체상추출칼럼및 역상액체크로마토그래피칼럼과유체연통되며, 고체상추출칼럼연결포트, 역상액체크로마토그래피칼럼연결포트, 제1 용매유입포트, 제2 용매유입포트, 상기고체상추출칼럼연결포트와시료이동루프에의해연결된시료이동루프연결포트, 및용매방출포트를포함하는트랩밸브; 및상기시료유입밸브로부터유출된용매의흐름을상기트랩밸브의제1 용매유입포트및 제2 용매유입포트로분리하는용매분리부;를포함하며, 이를통해시료의주입방향과시료의용출방향을상호역방향으로함으로써분리분해능을높이고고재현성을가지는액체크로마토그래피장치를제공할수 있다.
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公开(公告)号：KR100756078B1
公开(公告)日：2007-09-07
申请号：KR1020060107620
申请日：2006-11-02
Applicant: 고려대학교 산학협력단
Abstract: A method for preparing indium oxide nanocubes and an indium oxide nanocube prepared thereby are provided to obtain h-In2O6 nanocubes of a metastable state in a soluble form and having different sizes, which has superior solubility against an organic solvent and processability. A method for preparing indium oxide nanocubes comprises the steps of: (a) preparing a mixed solution containing In(OiPr)3, oleic acid, oleyl amine and 5-15 equivalents of distilled water based on the In(OiPr)3, (b) heating the mixed solution of the step (a) at a normal temperature to a temperature of 110 deg.C under a normal pressure with stirring; (c) heating the resultant of the step (b) at a temperature of 280 to 380 deg.C under a normal pressure to be dehydrated; and (d) cooling the resultant of the step (c) to a normal temperature and then adding thereto alcohol to obtain a precipitate.
Abstract translation: 提供一种制备氧化铟纳米管和由此制备的氧化铟纳米管的方法，以获得可溶形式的亚稳态的具有不同尺寸的h-In 2 O 6纳米立方体，其对有机溶剂的优异溶解性和加工性。 制备氧化铟纳米管的方法包括以下步骤：（a）根据In（OiPr）3，（b）的方法制备含有In（OiPr）3，油酸，油胺和5-15当量蒸馏水的混合溶液 ）在正常温度下在常温下将步骤（a）的混合溶液在常压下搅拌加热; （c）在280〜380℃的温度下将步骤（b）的所得物在常压下加热脱水; 和（d）将步骤（c）的所得物冷却至常温，然后加入其中以获得沉淀。
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