스트렙토코커스 파라우베리스 균주 유래의 항원을 포함하는 어류의 세균성 질병 예방용 혼합 불활성화 백신 및 이를 이용한 어류의 세균성 질병 예방 방법

    公开(公告)号:KR1020130091301A

    公开(公告)日:2013-08-16

    申请号:KR1020130088171

    申请日:2013-07-25

    Abstract: PURPOSE: A vaccine is provided to effectively and economically prevent 3 types of bacterial diseases with 1-time administration, and thus the vaccine may be effectively used in aquaculture industry. CONSTITUTION: A vaccine for preventing bacterial diseases in fish has activities of kristine arylamidase and naphthol-AS-BI-phosphohydrolase, and includes an antigen derived from an alpha-hemolytic Streptococcus parauberis FPA4164 strain (KCTC 11980BP) separated from a flatfish. A combined inactivated vaccine for preventing bacterial diseases in fish has activities of kristine arylamidase and naphthol-AS-BI-phosphohydrolase, and comprises an antigen derived from an alpha-hemolytic Streptococcus parauberis FPA4164 strain (KCTC 11980BP) separated from a flatfish; an inactivated beta-hemolytic Streptococcus iniae FP5024 (KCTC 11634BP) antigen; and an inactivated beta-hemolytic Edwardsiella tarda FP2018 (KCTC 11145BP) antigen.

    Abstract translation: 目的:提供一种疫苗,有效和经济地预防3种细菌性疾病,一次给药,因此疫苗可有效用于水产养殖业。 构成:用于预防鱼类细菌性疾病的疫苗具有克里斯汀芳基酰胺酶和萘酚-AS-BI-磷酸水解酶的活性,并且包括衍生自从鲽鱼分离的α-溶血性链脲霉素FPA4164菌株(KCTC 11980BP)的抗原。 用于预防鱼类细菌性疾病的组合灭活疫苗具有克里斯汀芳基酰胺酶和萘酚-AS-BI-磷酸水解酶的活性,并且包含从鲽鱼分离的α-溶血性水杨酸链球菌FPA4164菌株(KCTC 11980BP)的抗原; 灭活的β-溶血性链球菌FP5024(KCTC 11634BP)抗原; 和灭活的β-溶血性Edwardsiella tarda FP2018(KCTC 11145BP)抗原。

    어류의 비브리오 하베이 감염증 예방용 불활성화 백신, 그 제조방법 및 투여방법
    6.
    发明公开
    어류의 비브리오 하베이 감염증 예방용 불활성화 백신, 그 제조방법 및 투여방법 有权
    灭活疫苗对血液中的VIBRIO HARVEYI感染性疾病,其制备方法及其施用方法

    公开(公告)号:KR1020110136515A

    公开(公告)日:2011-12-21

    申请号:KR1020100056588

    申请日:2010-06-15

    Abstract: PURPOSE: An inactivated vaccine for preventing vibrio harveyi infection, containing vibrio harveyi HN strain as an antigen is provided to reduce mortality of fishes and to enhance productivity of fishes. CONSTITUTION: A Vibrio harveyi HN(deposit number KCTC 11705BP) strain is isolated from flatfishes with vibrio harveyi infection. An inactivated vaccine for preventing vibrio herveyi infection contains the Vibrio harveyi HN(deposit number KCTC 11705BP) strain as an antigen. The vaccine further contains inactivated Streptococcus parauberis strain. A method for manufacturing the vaccine comprises a step of culturing the Vibrio harveyi HN(deposit number KCTC 11705BP) strain and inactivating. The medium for culturing the strain contains 50-200 umol of 2,2'-dipyridyl.

    Abstract translation: 目的:提供一种用于预防弧菌弧菌感染的灭活疫苗,其包含哈氏弧菌HN菌株作为抗原,以减少鱼类的死亡率并提高鱼类的生产力。 构成:哈氏弧菌HN(保藏号KCTC 11705BP)菌株与哈氏弧菌感染的扁平鱼类分离。 用于预防弧菌感染感染的灭活疫苗含有作为抗原的Vibrio harveyi HN(保藏号KCTC 11705BP)菌株。 该疫苗还含有失活的欧洲白au链球菌菌株。 制备疫苗的方法包括培养哈氏弧菌HN(保藏号KCTC 11705BP)菌株并灭活的步骤。 用于培养菌株的培养基含有50-200μmol的2,2'-联吡啶。

    신규 스트렙토코커스 균주 및 상기 신규 스트렙토코커스 균주와 몬타나이드 보조제를 이용한 어류의 세균성 질병 예방용 혼합 불활성화 백신
    7.
    发明公开

    公开(公告)号:KR1020130012461A

    公开(公告)日:2013-02-04

    申请号:KR1020110073695

    申请日:2011-07-25

    Abstract: PURPOSE: A combined inactivated vaccine for preventing cellular diseases of fish using Streptococcus parauberis FPA4164 strain(KCTC 11980BP) is provided to effectively and cheaply prevent diseases caused by three kinds of bacteria. CONSTITUTION: An alpha-hemolytic Streptococcus parauberis FPA4164 strain(KCTC 11980BP) is isolated from flatfish. A combined inactivated vaccine for preventing cellular diseases of fish contains inactivated alpha-hemolytic Streptococcus parauberis FPA4164(KCTC 11980BP) antigen, inactivated beta-hemolytic Streptococcus iniae FP50249(KCTC 11634BP) antigen, and inactivated beta-hemolytic Edwardsiella tarda FP2018(KCTC 11145BP) antigen in a ratio of 1:1:1. The vaccine contains a montanide adjuvant. The adjuvant is montanide ISA35 or Gel01.

    Abstract translation: 目的:提供用于使用链脲霉素FPA4164菌株(KCTC 11980BP)预防鱼类细胞病的组合灭活疫苗,以有效和廉价地预防由三种细菌引起的疾病。 构成:从鲽鱼中分离出α-溶血性链脲霉素FPA4164株(KCTC 11980BP)。 用于预防鱼细胞疾病的组合灭活疫苗包含失活的α-溶血性链脲霉素FPA4164(KCTC 11980BP)抗原,灭活的β-溶血性链球菌FP50249(KCTC 11634BP)抗原和灭活的β-溶血性Edwardsiella tarda FP2018(KCTC 11145BP)抗原 以1:1:1的比例。 该疫苗含有一种montanide佐剂。 佐剂是montanide ISA35或Gel01。

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