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公开(公告)号：KR1020100136191A
公开(公告)日：2010-12-28
申请号：KR1020090054422
申请日：2009-06-18
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
Abstract: PURPOSE: An antigen for hemoglutination for swine Japanese encephalitis virus is provided to reduce pollution caused by acetone extraction. CONSTITUTION: A method for preparing antigen for hemoglutination of high concentration for swine Japanese encephalitis virus comprises: a step of inoculating swine Japanese encephalitis virus to a tissue culture cells and planting; a step of freezing culture liquid; a step of thawing the culture liquid and repeating freezing and thawing once; a step of collecting cultured swine Japanese encephalitis virus; a step of inactivating swine Japanese encephalitis virus; a step of concentrating swine Japanese encephalitis virus; and a step of precipitating swine Japanese encephalitis virus by centrifugation.
Abstract translation: 目的：提供用于猪日本脑炎病毒血凝反应的抗原，以减少丙酮提取引起的污染。 构成：一种制备猪日本脑炎病毒高浓度血凝反应抗原的方法，包括：将日本脑炎病毒接种在组织培养细胞中并种植; 冷冻培养液的一个步骤; 解冻培养液并重复冻融一次; 收集日本猪日本脑炎病毒的一步; 灭活日本脑炎病毒的一步; 日本脑炎病毒浓缩一步; 并通过离心沉淀猪日本脑炎病毒的一个步骤。
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2.发明公开
公开(公告)号：KR1020080062815A
公开(公告)日：2008-07-03
申请号：KR1020060138940
申请日：2006-12-29
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
Abstract: A target-organ array set and a method for diagnosing exposure to a brominated compound and intoxication by the brominated compound are provided to identify the intoxication and contamination degree of the brominated compound easily by identifying a change of a protein which shows specific change in an organ sensitively influenced by the brominated compound. A target-organ array set for diagnosing exposure to a brominated compound and intoxication by the brominated compound comprises: a control sample adhesion portion where at least one selected from the group consisting of pituitary tissue, a thyroid tissue, a liver tissue and a prostatic tissue of a normal group is attached to the surface; and an adhesion portion to be measured where a sample to be measured regarding a control group is adhered. An antibody set for diagnosing exposure to the brominated compound and intoxication by the brominated compound comprises at least one antibody selected from the group consisting of an anti-pregnane X receptor antibody, anti-apolipoprotein A-1 antibody, anti Bcl-2 antibody, anti-cytochrome P4501A1 antibody, anti UDP-glucuronosyltransferase 1A antibody, and anti androgen receptor antibody.
Abstract translation: 提供靶器官阵列组和用于诊断溴化化合物暴露和溴化化合物中毒的方法，以通过鉴定显示器官特异性变化的蛋白质的变化容易地识别溴化化合物的中毒和污染程度 受溴化合物的敏感影响。 用于诊断暴露于溴化化合物并被溴化化合物中毒的靶器官阵列组包括：对照样品粘附部分，其中选自垂体组织，甲状腺组织，肝组织和前列腺组织中的至少一种 正常组附着在表面上; 以及附着在待测量样品上的粘附部分。 用于诊断暴露于溴化化合物并被溴化化合物中毒的抗体集合包含至少一种选自抗孕烷X受体抗体，抗载脂蛋白A-1抗体，抗Bcl-2抗体，抗 - - 细胞色素P4501A1抗体，抗UDP-葡糖醛酸基转移酶1A抗体和抗雄激素受体抗体。
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公开(公告)号：KR101484294B1
公开(公告)日：2015-01-21
申请号：KR1020120137954
申请日：2012-11-30
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
Abstract: 본 발명은 퀴놀론계 항균제에 특이적으로 결합하는 단일클론항체, 상기 단일클론항체를 생산하는 하이브리도마 세포주, 상기 단일클론항체를 포함하는 퀴놀론계 항균제 검출용 키트 및 상기 단일클론항체를 이용하여 퀴놀론계 항균제를 검출하는 방법에 관한 것이다. 본 발명에 따른 퀴놀론계 항균제에 특이적으로 결합하는 단일클론항체는 다른 계열의 항생제와 교차반응 없이, 엔로플록사신, 시플록사신, 사라플록사신, 디플록사신, 페플록사신, 노르플록사신을 포함하는 퀴놀론계 항균제에 폭넓게 결합할 수 있으므로 시료 내의 퀴놀론계 항균제를 매우 효과적으로 검출할 수 있다.
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公开(公告)号：KR101144993B1
公开(公告)日：2012-06-27
申请号：KR1020090054422
申请日：2009-06-18
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
Abstract: PURPOSE: An antigen for hemoglutination for swine Japanese encephalitis virus is provided to reduce pollution caused by acetone extraction. CONSTITUTION: A method for preparing antigen for hemoglutination of high concentration for swine Japanese encephalitis virus comprises: a step of inoculating swine Japanese encephalitis virus to a tissue culture cells and planting; a step of freezing culture liquid; a step of thawing the culture liquid and repeating freezing and thawing once; a step of collecting cultured swine Japanese encephalitis virus; a step of inactivating swine Japanese encephalitis virus; a step of concentrating swine Japanese encephalitis virus; and a step of precipitating swine Japanese encephalitis virus by centrifugation.
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公开(公告)号：KR1020140082021A
公开(公告)日：2014-07-02
申请号：KR1020120150936
申请日：2012-12-21
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
IPC: C12N5/0735 , C12N5/02
CPC classification number: C12N5/0696
Abstract: The present invention relates to a complete induced pluripotent stem cell obtained by treating sodium butyrate and a treating method thereof which contain a process of treating the sodium butyrate onto the complete induced pluripotent stem cell. According to the present invention, the production method can be effectively used for research of the relevant fields, as a partial induced pluripotent stem cell having an interval characteristic of a somatic cell and a stem cell can be efficiently converted into the complete induced pluripotent stem cell.
Abstract translation: 本发明涉及通过处理丁酸钠而获得的完全诱导的多能干细胞及其治疗方法，其包含将丁酸钠处理到完全诱导的多能干细胞上的方法。 根据本发明，生产方法可以有效地用于相关领域的研究，因为具有体细胞间隔特征的部分诱导多能干细胞和干细胞可以有效地转化为完全诱导的多能干细胞 。
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Patent Agency Ranking
公开(公告)号：KR1020140082016A
公开(公告)日：2014-07-02
申请号：KR1020120150885
申请日：2012-12-21
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
CPC classification number: C12N15/11 , C12Q1/6844 , C12Q1/6886 , C12Q2600/154
Abstract: The present invention relates to a marker composition for diagnosis of bone marrow cancer and a kit and a method for diagnosis of bone marrow cancer including the marker. The marker composition of the present invention amplifies a certain area where CpG area of the gene BCL11a, RB1, GLIS2 and ABI2 is included, in order to compare similarities and differences of the methylation level of the gene. Hence, the present invention can effectively be used to promptly and accurately diagnose bone marrow cancer including T-cell lymphoma, B-cell lymphoma and leukemia.
Abstract translation: 本发明涉及用于诊断骨髓癌的标记组合物和用于诊断包括该标记物的骨髓癌的试剂盒和方法。 为了比较基因的甲基化水平的相似度和差异，本发明的标记物组合物扩增了包含基因BCL11a，RB1，GLIS2和ABI2的CpG面积的某一区域。 因此，本发明可以有效地用于及时，准确地诊断包括T细胞淋巴瘤，B细胞淋巴瘤和白血病在内的骨髓癌。
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公开(公告)号：KR1020070050686A
公开(公告)日：2007-05-16
申请号：KR1020050108196
申请日：2005-11-11
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
IPC: G01N33/53
Abstract: 본 발명은 브롬화합물에 대한 특이단백질을 이용한 진단 방법으로서, 브롬화합물 독성검색 및 노출평가를 위하여 혈청 중 특이단백질로서 아포리포단백질 AI을 이용한 브롬화합물 노출에 대한 진단 방법이다.
본 발명은 플라스틱제품 등 인화성이 높은 제품에 방화제로 주로 쓰이는 화학물질인 브롬화합물이 산업의 발달로 식품 및 환경 중 오염량이 증가하여 인체노출이 증가함에 따라 이의 독성 및 노출을 간단하게 평가하고자, 브롬화합물의 생체 내 특이지표로서 아포리포프로테인 AI을 규명한 것이다.
본 발명은 브롬화합물의 생체 내 특이지표를 이용하여 독성검색 및 오염도 평가를 용이하게 하는데 도움이 될 것이다.
브롬화합물, 특이단백질, 단백질칩, 아포리포프로테인 AI-
公开(公告)号：KR101540719B1
公开(公告)日：2015-08-04
申请号：KR1020120150885
申请日：2012-12-21
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
Abstract: 본발명은골수암진단용마커조성물, 상기마커를포함하는골수암진단키트및 진단방법에관한것이다. 본발명에따른마커조성물은 BCL11a, RB1, GLIS2 및 ABI2 유전자의 CpG 부위가포함된특정부위를증폭하여, 상기유전자의메틸화정도를비교분석할수 있어, T세포림프종, B세포림프종및 백혈병을포함하는골수암을빠르고정확하게진단하는데유용하게이용될수 있다.
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公开(公告)号：KR1020140072311A
公开(公告)日：2014-06-13
申请号：KR1020120137954
申请日：2012-11-30
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
Abstract: The present invention relates to a monoclonal antibody specifically binding to a quinolone-based antibiotic, hybridoma cell lines producing the monoclonal antibody, a kit for detecting a quinolone-based antibiotic comprising the monoclonal antibody, and a method for detecting a quinolone-based antibiotic using the monoclonal antibody. The monoclonal antibody specifically binding to a quinolone-based antibiotic can effectively detect the quinolone-based antibiotic in a sample by widely binding to a quinolone-based antibiotic comprising enrofloxacin, ciprofloxacin, sarafloxacin, difloxacin, pefloxacin, and norfloxacin, without a cross-reactivity with an antibiotic of other family.
Abstract translation: 本发明涉及特异性结合喹诺酮类抗生素的单克隆抗体，产生单克隆抗体的杂交瘤细胞系，用于检测包含单克隆抗体的喹诺酮类抗生素的试剂盒，以及使用以下方法检测喹诺酮类抗生素的方法： 单克隆抗体。 与喹诺酮类抗生素特异性结合的单克隆抗体可通过广泛结合含有恩诺福沙星，环丙沙星，沙拉沙星，二氟沙星，氟沙星，诺氟沙星的喹诺酮类抗生素，无交叉反应性，有效地检测样品中的喹诺酮类抗生素 与其他家庭的抗生素。
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公开(公告)号：KR100737496B1
公开(公告)日：2007-07-09
申请号：KR1020050108196
申请日：2005-11-11
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
IPC: G01N33/53
Abstract: 본 발명은 브롬화합물에 대한 특이단백질을 이용한 진단 방법으로서, 브롬화합물 독성검색 및 노출평가를 위하여 혈청 중 특이단백질로서 아포리포단백질 AI을 이용한 브롬화합물 노출에 대한 진단 방법이다.
본 발명은 플라스틱제품 등 인화성이 높은 제품에 방화제로 주로 쓰이는 화학물질인 브롬화합물이 산업의 발달로 식품 및 환경 중 오염량이 증가하여 인체노출이 증가함에 따라 이의 독성 및 노출을 간단하게 평가하고자, 브롬화합물의 생체 내 특이지표로서 아포리포프로테인 AI을 규명한 것이다.
본 발명은 브롬화합물의 생체 내 특이지표를 이용하여 독성검색 및 오염도 평가를 용이하게 하는데 도움이 될 것이다.
브롬화합물, 특이단백질, 단백질칩, 아포리포프로테인 AI
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