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公开(公告)号:KR1020130077920A
公开(公告)日:2013-07-09
申请号:KR1020110144400
申请日:2011-12-28
Applicant: 부경대학교 산학협력단
CPC classification number: A61K38/10 , A23K20/147 , A23K50/80 , C07K7/08
Abstract: PURPOSE: A composition containing apidaecin as an active ingredient for preventing and treating Edwardsiellosis in fish is provided to ensure specific and efficient antibacterial activities through a bacteriostatic mechanism without membrane selectivity. CONSTITUTION: A composition for preventing and treating Edwardsiellosis in fish contains apidaecin as an active ingredient. The apidaecin is an apidaecin Ib with an amino acid sequence of the number 2. The composition is provided in the form of a feed additive. A method for preventing and treating Edwardsiellosis in fish comprises a step of administering apidaecin to the fish.
Abstract translation: 目的:提供含有apidaecin作为预防和治疗鱼类Edwardsiellosis活性成分的组合物,以通过抑菌机制确保特异性和有效的抗菌活性,而无需膜选择性。 构成:用于预防和治疗鱼类爱德华病的组合物含有apidaecin作为活性成分。 apidaecin是具有2号氨基酸序列的apidaecin Ib。该组合物以饲料添加剂的形式提供。 用于预防和治疗鱼类爱德华病的方法包括向鱼中施用apidaecin的步骤。
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公开(公告)号:KR1020130109544A
公开(公告)日:2013-10-08
申请号:KR1020120031339
申请日:2012-03-27
Applicant: 부경대학교 산학협력단
IPC: C07K14/435 , C12N15/12 , A61K38/17 , A61P31/04
Abstract: PURPOSE: An antimicrobial peptide derived from abalone is provided to show an antimicrobial activity against fish pathogenic microorganisms without harm to human body and fish because the peptide does not have a hemolytic activity in erythrocytes of human and fish. CONSTITUTION: A peptide with an amino acid of sequence number 1 has an antimicrobial activity. The peptide is derived from Haliotis discus. The peptide has an antimicrobial activity against gram positive bacteria and gram negative bacteria. The peptide does not damage erythrocytes of human and fish. A gene encodes the peptide. Antibiotics contain the peptide as an active ingredient. [Reference numerals] (AA) Abalone Gill extract
Abstract translation: 目的:提供来自鲍鱼的抗微生物肽,以显示对鱼类病原微生物的抗微生物活性,而不会对人体和鱼造成伤害,因为肽在人和鱼的红细胞中不具有溶血活性。 构成:具有序列号1的氨基酸的肽具有抗菌活性。 肽源自Haliotis铁饼。 该肽对革兰氏阳性菌和革兰氏阴性细菌具有抗菌活性。 该肽不会伤害人类和鱼类的红细胞。 一个基因编码该肽。 抗生素含有肽作为活性成分。 (附图标记)(AA)鲍鱼鳃提取物
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公开(公告)号:KR101384578B1
公开(公告)日:2014-04-11
申请号:KR1020120031339
申请日:2012-03-27
Applicant: 부경대학교 산학협력단
IPC: C07K14/435 , C12N15/12 , A61K38/17 , A61P31/04
Abstract: 본 발명은 항미생물성 펩타이드에 관한 것으로서, 어류 병원성 미생물에 대하여 효율적인 항미생물 활성을 나타낼 뿐만 아니라, 인체 및 어류의 적혈구에 대한 용혈활성은 거의 없기 때문에, 양식어류에 대한 사료첨가제로 사용되거나, 항생제 대체제로 사용되더라도 어류 및 인체의 건강에 대한 위협요소를 제공하지 않는다.
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公开(公告)号:KR101384577B1
公开(公告)日:2014-04-11
申请号:KR1020120031338
申请日:2012-03-27
Applicant: 부경대학교 산학협력단
CPC classification number: Y02A50/473
Abstract: 본 발명은 항미생물성 펩타이드에 관한 것으로서, 어류 병원성 미생물에 대하여 효율적인 항미생물 활성을 나타낼 뿐만 아니라, 인간 및 어류의 적혈구에 대한 용혈활성은 거의 없기 때문에, 양식어류에 대한 사료첨가제로 사용되거나, 항생제 대체제로 사용되더라도 어류 및 인체의 건강에 대한 위협요소를 제공하지 않는다.
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公开(公告)号:KR1020130109543A
公开(公告)日:2013-10-08
申请号:KR1020120031338
申请日:2012-03-27
Applicant: 부경대학교 산학협력단
CPC classification number: Y02A50/473
Abstract: PURPOSE: An antimicrobial peptide derived from Thunnus albacares is provided to show effective antimicrobial activity against fish pathogenic microorganisms without harming the fish and the human body because the peptide does not have a hemolytic activity to erythrocytes of human and fish. CONSTITUTION: A peptide with an amino acid sequence of sequence number 1 or a variant thereof has an antimicrobial activity. The peptide or the derivative is derived from Thunnus albacares. The peptide or the derivative has an antimicrobial activity against gram positive bacteria and gram negative bacteria. The peptide or the variant does not damage erythrocytes of human or fish. A gene encodes the peptide or the variant. Antibiotics contain the peptide as an active ingredient.
Abstract translation: 目的:提供衍生自Thunnus albacares的抗微生物肽,以显示对鱼类病原微生物的有效抗微生物活性,而不会对鱼类和人体造成伤害,因为该肽对人类和鱼类的红细胞没有溶血活性。 构成:具有序列号1的氨基酸序列或其变体的肽具有抗微生物活性。 肽或衍生物衍生自Thunnus albacares。 肽或衍生物对革兰氏阳性菌和革兰氏阴性细菌具有抗菌活性。 肽或变体不会损伤人或鱼的红细胞。 基因编码肽或变体。 抗生素含有肽作为活性成分。
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