1,4―BDO 생산을 위한 유전자 스크리닝 방법
    2.
    发明公开
    1,4―BDO 생산을 위한 유전자 스크리닝 방법 审中-实审
    鉴定1,4-BDO生产基因的筛选方法

    公开(公告)号:KR1020150023175A

    公开(公告)日:2015-03-05

    申请号:KR1020130100567

    申请日:2013-08-23

    Abstract: The present invention relates to a method for screening genes used for increasing 1,4-butanediol (BDO) production by using proteomics data. In the present invention, 1,4-BDO productivity is increased when a Ncgl0630 (citrate synthase) protein and a Ncgl2145 (hypothetical protein) protein are overly expressed wherein the Ncgl0630 (citrate synthase) protein and the Ncgl2145 (hypothetical protein) protein are screened via the method which is used to find proteins related to 1,4-BDO productivity and accordingly increases productivity, thereby being widely applicable industrially.

    Abstract translation: 本发明涉及通过使用蛋白质组学数据筛选用于增加1,4-丁二醇(BDO)生产的基因的方法。 在本发明中,当Ncgl0630(柠檬酸合成酶)蛋白和Ncgl2145(假想蛋白))蛋白被过度表达时,其中筛选出Ncgl0630(柠檬酸合成酶)蛋白和Ncgl2145(假想蛋白))蛋白质时,1,4-BDO生产力增加 通过用于发现与1,4-BDO生产率相关的蛋白质的方法,从而提高生产率,从而在工业上广泛应用。

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