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公开(公告)号：WO2016159440A1
公开(公告)日：2016-10-06
申请号：PCT/KR2015/005075
申请日：2015-05-21
Applicant: 서울대학교산학협력단
IPC: C12N5/0783 , A61K35/17
CPC classification number: C12N5/0638 , A61K35/17 , A61K39/0011 , A61K39/235 , A61K39/245 , A61K2039/5156 , A61K2039/5158 , C12N2501/05 , C12N2501/2304 , C12N2501/2307 , C12N2501/2315 , C12N2502/1107 , C12N2502/99 , C12N2710/10034 , C12N2710/16134 , C12N2710/16234
Abstract: 본원은 생물반응조절제가 적제되고 바이러스 항원을 발현하는 B 세포를 이용한 체외 항원 특이적 세포독성 T 세포 제조 방법 및 그 용도를 개시한다. 본원에 따른 방법에 의해 제조된 세포독성 T 세포는 감염치료 및 암 치료 등에 유용하게 사용될 수 있다.
Abstract translation: 在本申请中公开的是：通过使用其中累积生物反应调节剂并表达病毒抗原的B细胞体外制备抗原特异性细胞毒性T细胞的方法; 及其用途。 通过本申请方法制备的细胞毒性T细胞可用于治疗感染和治疗癌症等。
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公开(公告)号：KR101208054B1
公开(公告)日：2012-12-04
申请号：KR1020100082520
申请日：2010-08-25
Applicant: 서울대학교산학협력단
Abstract: 본발명은소아백혈병에대한바이오마커에관한것이다. 보다상세하게는소아백혈병과상관관계를나타내는 SNP를포함하는폴리뉴클레오티드, 키트및 이를이용하여소아백혈병의발병위험도를예측하는방법에관한것이다. 본발명에따른소아백혈병진단용마커를이용한진단및 예측방법을통해, 간단한처리만으로도개인의유전형질을확인하고소아백혈병의발병위험도를진단할수 있다.
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Patent Agency Ranking
公开(公告)号：KR1020120019222A
公开(公告)日：2012-03-06
申请号：KR1020100082506
申请日：2010-08-25
Applicant: 서울대학교산학협력단
CPC classification number: C12Q1/6886 , C12Q2600/118 , C12Q2600/156
Abstract: PURPOSE: A biomarker for acute lymphocytic leukemia is provided for detecting an individual genetic character and to diagnose the risk of leukemia. CONSTITUTION: A marker for diagnosing acute lymphocytic leukemia contains a polynucleotide or complement thereof having 8-200 serial sequences with an SNP of rs3776932, rs6140264, rs12105972, rs9388856, rs9388857, or rs1360756. A method for diagnosing acute lymphocytic leukemia comprises: a step of preparing a nucleic acid sample from an analyte; a step of determining the base sequence of an SNP of rs3776932, rs6140264, rs12105972, rs9388856, rs9388857, or rs1360756 in the nucleic acid sample; and a step of determining the determined the risk of the sequence.
Abstract translation: 目的：提供急性淋巴细胞白血病的生物标志物，用于检测个体遗传特征并诊断白血病的风险。 构成：用于诊断急性淋巴细胞性白血病的标志物含有具有SNP rs3776932，rs6140264，rs12105972，rs9388856，rs9388857或rs1360756的8-200序列序列的多核苷酸或其互补序列。 诊断急性淋巴细胞白血病的方法包括：从分析物制备核酸样品的步骤; 确定核酸样品中rs3776932，rs6140264，rs12105972，rs9388856，rs9388857或rs1360756的SNP的碱基序列的步骤; 以及确定确定序列风险的步骤。
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公开(公告)号：KR101715468B1
公开(公告)日：2017-03-13
申请号：KR1020150045476
申请日：2015-03-31
Applicant: 서울대학교산학협력단
IPC: C12N5/0783 , A61K35/17
CPC classification number: C12N5/0638 , A61K35/17 , A61K39/0011 , A61K39/235 , A61K39/245 , A61K2039/5156 , A61K2039/5158 , C12N2501/05 , C12N2501/2304 , C12N2501/2307 , C12N2501/2315 , C12N2502/1107 , C12N2502/99 , C12N2710/10034 , C12N2710/16134 , C12N2710/16234
Abstract: 본원은생물반응조절제가적제되고바이러스항원을발현하는 B 세포를이용한체외항원특이적세포독성 T 세포제조방법및 그용도를개시한다. 본원에따른방법에의해제조된세포독성 T 세포는감염치료및 암치료등에유용하게사용될수 있다.
Abstract translation: 在本申请中公开的是：通过使用其中累积生物反应调节剂并表达病毒抗原的B细胞体外制备抗原特异性细胞毒性T细胞的方法; 及其用途。 通过本申请方法制备的细胞毒性T细胞可用于治疗感染和治疗癌症等。
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公开(公告)号：KR1020160116978A
公开(公告)日：2016-10-10
申请号：KR1020150045476
申请日：2015-03-31
Applicant: 서울대학교산학협력단
IPC: C12N5/0783 , A61K35/17
CPC classification number: C12N5/0638 , A61K35/17 , A61K39/0011 , A61K39/235 , A61K39/245 , A61K2039/5156 , A61K2039/5158 , C12N2501/05 , C12N2501/2304 , C12N2501/2307 , C12N2501/2315 , C12N2502/1107 , C12N2502/99 , C12N2710/10034 , C12N2710/16134 , C12N2710/16234
Abstract: 본원은생물반응조절제가적제되고바이러스항원을발현하는 B 세포를이용한체외항원특이적세포독성 T 세포제조방법및 그용도를개시한다. 본원에따른방법에의해제조된세포독성 T 세포는감염치료및 암치료등에유용하게사용될수 있다.
Abstract translation: 在本申请中公开的是：通过使用其中累积生物反应调节剂并表达病毒抗原的B细胞体外制备抗原特异性细胞毒性T细胞的方法; 及其用途。 通过本申请方法制备的细胞毒性T细胞可用于治疗感染和治疗癌症等。
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公开(公告)号：KR101208051B1
公开(公告)日：2012-12-04
申请号：KR1020100082506
申请日：2010-08-25
Applicant: 서울대학교산학협력단
Abstract: 본발명은급성림프구성백혈병에대한바이오마커에관한것이다. 보다상세하게는급성림프구성백혈병과상관관계를나타내는 SNP를포함하는폴리뉴클레오티드, 키트및 이를이용하여소아급성림프구성백혈병의발병위험도를예측하는방법에관한것이다. 본발명에따른급성림프구성백혈병진단용마커를이용한진단및 예측방법을통해, 간단한처리만으로도개인의유전형질을확인하고급성림프구성백혈병의발병위험도를진단할수 있다.
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公开(公告)号：KR1020120019232A
公开(公告)日：2012-03-06
申请号：KR1020100082520
申请日：2010-08-25
Applicant: 서울대학교산학협력단
CPC classification number: C12Q1/6886 , C12Q2600/118 , C12Q2600/156
Abstract: PURPOSE: A biomarker for leukemia in children and a method for predicting the risk of leukemia in children are provided to check the genetic character of an individual and to diagnose risk. CONSTITUTION: A marker for diagnosing leukemia in children contains: a polynucleotide containing 8-200 serial base sequences with an SNP of rs703817, rs17433222, or rs3794845; or a complement thereof. A kit for diagnosing leukemia in children contains the marker. A method for diagnosing leukemia in children comprises: a step of preparing nucleic acid samples from a test sample; a step of determining the base sequence of an SNP of rs703817, rs17433222, or rs3794845 in the nucleic acid sample; and a step of determining the risk of leukemia in case that rs703817, rs17433222, and rs3794845 is GG, GG, and CC, respectively.
Abstract translation: 目的：提供儿童白血病生物标志物和预测儿童白血病风险的方法，以检查个体的遗传特性并诊断风险。 构成：用于诊断儿童白血病的标记物包含：含有SNP rs703817，rs17433222或rs3794845的8-200个序列碱基序列的多核苷酸; 或其补体。 用于诊断儿童白血病的试剂盒含有标记物。 用于诊断儿童白血病的方法包括：从测试样品制备核酸样品的步骤; 确定核酸样品中rs703817，rs17433222或rs3794845的SNP的碱基序列的步骤; 在rs703817，rs17433222和rs3794845分别为GG，GG和CC的情况下，确定白血病风险的步骤。
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