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公开(公告)号：KR101670967B1
公开(公告)日：2016-11-09
申请号：KR1020090103559
申请日：2009-10-29
Applicant: 삼성전자주식회사 , 서울대학교산학협력단
Abstract: 질병또는약물에관련된유전체마커를선택하기위한방법및 장치가개시된다. 상기유전체마커를포함하는유전체마커군이상기질병또는약물에관련된정도를나타내는평가지표를계산하고, 상기평가지표에기초하여유전체마커를선택한다.
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公开(公告)号：KR1020110064699A
公开(公告)日：2011-06-15
申请号：KR1020090121405
申请日：2009-12-08
Applicant: 삼성전자주식회사 , 서울대학교산학협력단
CPC classification number: C12Q1/6827 , C12Q1/6837 , C12Q2600/156 , G06F19/18
Abstract: PURPOSE: An apparatus for analyzing single nucleotide polymorphism(SNP) genotype is provided to accurately analyze SNP genotype in a gene sample. CONSTITUTION: An apparatus for analyzing SNP genotype from a microarray containing a plurality of probes comprises: a representative value calculation unit for calculating each representative value of gene samples based on the intensity of signal generated by reaction of probes with respect to each gene sample; a model learning unit which increases degree of scattering of representative values and learn boundaries; a model generation unit for generating SNP model which classifies spaces into a plurality of groups based on the learned boundaries; and a genotype analysis unit for analyzing SNP genotype using a SNP model.
Abstract translation: 目的：提供用于分析单核苷酸多态性（SNP）基因型的设备，以准确分析基因样品中的SNP基因型。 构成：用于从包含多个探针的微阵列分析SNP基因型的装置包括：代表值计算单元，用于基于探针相对于每个基因样品的反应产生的信号的强度来计算基因样品的每个代表值; 模型学习单元，增加了代表性的散度和学习边界; 用于生成SNP模型的模型生成单元，其基于所学习的边界将空间分类成多个组; 以及使用SNP模型分析SNP基因型的基因型分析单元。
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Patent Agency Ranking
公开(公告)号：KR1020120079320A
公开(公告)日：2012-07-12
申请号：KR1020110000548
申请日：2011-01-04
Applicant: 삼성전자주식회사 , 서울대학교산학협력단
CPC classification number: G06F19/22 , C12Q1/6869
Abstract: PURPOSE: A method and an apparatus for repairing gene sequences using a probe map are provided to accurately repair target sequences. CONSTITUTION: A method for repairing gene sequences using a probe map comprises: a step of arranging a probe on a target sequence based on probe-hybridized result(1201); a step of determining representative value of each arranged site based on statistic distribution(1202); and a step of repairing target sequences using the probe map in which determined representative value and probe sequence information are mapped(1203).
Abstract translation: 目的：提供使用探针图修复基因序列的方法和装置，以准确地修复靶序列。 构成：使用探针图修复基因序列的方法包括：基于探针杂交结果在靶序列上排列探针的步骤（1201）; 基于统计分布确定每个布置点的代表值的步骤（1202）; 以及使用其中映射了确定的代表值和探针序列信息的探针图来修复靶序列的步骤（1203）。
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公开(公告)号：KR101768122B1
公开(公告)日：2017-08-16
申请号：KR1020110000548
申请日：2011-01-04
Applicant: 삼성전자주식회사 , 서울대학교산학협력단
CPC classification number: G06F19/22
Abstract: 프로브맵을이용한유전자서열복원방법은표적서열에프로브가혼성화된결과에기초하여프로브를정렬하고, 정렬된위치들각각에대한대표값을결정하고, 결정된대표값과프로브의염기서열정보가매핑된프로브맵을이용하여표적서열의염기서열을복원한다.
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公开(公告)号：KR1020110046866A
公开(公告)日：2011-05-06
申请号：KR1020090103559
申请日：2009-10-29
Applicant: 삼성전자주식회사 , 서울대학교산학협력단
CPC classification number: G06F19/18 , C12Q1/68 , C12Q2600/156
Abstract: PURPOSE: A method for selecting a gene marker relating to diseases or drugs is provided to select a gene marker group of excellent performance. CONSTITUTION: A method for selecting a gene marker comprises: a step of providing an object gene; a step of collecting a plurality of gene markers corresponding to the object gene; a step of determining standard infect of evaluation; a step of calculating the index of evaluation of a gene marker group containing two or more gene markers; and a step of selecting gene marker having optimal evaluation index. The gene marker is SNP(Single Nucleotide Polymorphism), CNV(Copy Number Variation), STS(Sequence Tagged Site), STR(Short Tandem Repeat), LTR(Long Terminal Repeat), or Indel(Insertion Deletion).
Abstract translation: 目的：提供选择与疾病或药物相关的基因标记的方法，以选择性能优异的基因标记组。 构成：选择基因标记物的方法包括：提供对象基因的步骤; 收集与所述对象基因相对应的多个基因标记物的步骤; 确定评价标准感染的一个步骤; 计算含有两个以上基因标记物的基因标记组的评价指标的步骤; 选择具有最佳评价指标的基因标记的步骤。 基因标记是SNP（单核苷酸多态性），CNV（拷贝数变异），STS（序列标记位点），STR（短串联重复），LTR（长末端重复）或Indel（插入缺失）。
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公开(公告)号：KR1020110046865A
公开(公告)日：2011-05-06
申请号：KR1020090103558
申请日：2009-10-29
Applicant: 서울대학교산학협력단
CPC classification number: C12Q1/6837 , C12Q1/6834 , G06F17/11 , G06F19/00
Abstract: PURPOSE: A method for determining microarray product quality is provided to digitize signal intensity by the length of a product quality management probe and to effectively determine the product quality. CONSTITUTION: A method for determining microarray product quality comprises: a step of providing a microarray containing a product quality probe nucleic acid fixed on a substrate; a step of hybridizing a sample containing signal material-labeled oligonucleotide with the probe nucleic acid; a step of measuring label signal; and a step of selecting microarray which satisfies selection criteria. The oligonucleotide contains 2-100 bases. The signal material contains fluorescent substance or radioactive substance.
Abstract translation: 目的：提供一种确定微阵列产品质量的方法，通过产品质量管理探针的长度将信号强度数字化，并有效确定产品质量。 构成：用于测定微阵列产品质量的方法包括：提供包含固定在底物上的产品质量探针核酸的微阵列的步骤; 将含有信号材料标记的寡核苷酸的样品与探针核酸杂交的步骤; 测量标签信号的步骤; 以及选择满足选择标准的微阵列的步骤。 寡核苷酸含有2-100个碱基。 信号材料含有荧光物质或放射性物质。
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