자가유래 APC를 이용한 조절 T 세포의 생체외 증식 방법 및 이의 용도
    1.
    发明公开
    자가유래 APC를 이용한 조절 T 세포의 생체외 증식 방법 및 이의 용도 有权
    使用自体抗原呈递细胞扩增调节性T细胞的方法及其用途

    公开(公告)号:KR1020150126568A

    公开(公告)日:2015-11-12

    申请号:KR1020150062802

    申请日:2015-05-04

    Abstract: 본발명은자가유래 APC를이용한조절 T 세포의생체외증식방법및 이의용도에관한것으로, 보다상세하게는 (a) 영장류 CD4Treg 및 CD4PBMC를각각준비하는단계; 및 (b) 상기 CD4Treg를상기 CD4PBMC, 항-CD3 항체, 항-CD28 항체, IL2(interleukin2) 및 TGF-b(beta)로자극하여 CD4Treg를증식시키는단계;를포함하는 CD4면역조절 T 세포(Regulatory T Cell, Treg)의생체외증식방법, 장기이식거부반응억제용조성물및 자가면역질환또는염증성질환의예방또는치료용약학적조성물을제공한다. 본발명의방법은조절 T 세포를대량증식시키고상기증폭된조절 T 세포는탁월한면역억제효과를나타내므로, 동종또는이종간의장기의이식시 수용체(recipient)에서발생하는다양한면역거부반응을극복하는데 효과적으로이용될수 있다.

    Abstract translation: 本发明涉及通过使用自体抗原呈递细胞(APC)及其用途在体外增殖调节性T细胞(Treg)的方法。 更具体地,用于CD4 + Treg的体外增殖的方法包括以下步骤: (a)分别制备CD4 + Treg和CD4-PBMC; 和(b)用CD4-PBMC,抗CD3抗体,抗CD28抗体,白细胞介素2(IL2)和TGF-b(β)刺激CD4 + Treg以增殖CD4 + Treg。 本发明还涉及用于抑制移植排斥反应的组合物和用于预防或治疗自身免疫性疾病或炎性疾病的药物组合物。 该方法可用于调节性T细胞的大量增殖,并表现出优异的免疫抑制作用,从而有效地用于克服在用于同源物种或种间器官移植的接受者中发生的各种免疫排斥反应。

    광전극 및 이의 형성 방법
    3.
    发明公开
    광전극 및 이의 형성 방법 有权
    电极及其形成方法

    公开(公告)号:KR1020100048664A

    公开(公告)日:2010-05-11

    申请号:KR1020080107926

    申请日:2008-10-31

    CPC classification number: H01G9/2027 H01L31/18 Y02E10/542

    Abstract: PURPOSE: A photo-electrode and a method for forming the same are provided to prevent the loss of electrons in an oxide semiconductor particle through the interface between a semiconductor and electrolyte. CONSTITUTION: An electrode(20) is formed on a glass substrate(10). An oxide semiconductor layer is formed on the electrode. The oxide semiconductor layer includes an oxide semiconductor particle on which a negative ion(60) is absorbed. A photo-resist material(30) is absorbed on the surface of the oxide semiconductor particle. An acid treatment is performed to the electrode.

    Abstract translation: 目的:提供一种光电极及其形成方法,以通过半导体和电解质之间的界面来防止氧化物半导体颗粒中的电子损失。 构成:在玻璃基板(10)上形成电极(20)。 在电极上形成氧化物半导体层。 氧化物半导体层包括其上吸收负离子(60)的氧化物半导体颗粒。 光致抗蚀剂材料(30)被吸收在氧化物半导体颗粒的表面上。 对电极进行酸处理。

    자가유래 APC를 이용한 조절 T 세포의 생체외 증식 방법 및 이의 용도

    公开(公告)号:KR101757269B1

    公开(公告)日:2017-07-12

    申请号:KR1020150062802

    申请日:2015-05-04

    Abstract: 본발명은자가유래 APC를이용한조절 T 세포의생체외증식방법및 이의용도에관한것으로, 보다상세하게는 (a) 영장류 CD4Treg 및 CD4PBMC를각각준비하는단계; 및 (b) 상기 CD4Treg를상기 CD4PBMC, 항-CD3 항체, 항-CD28 항체, IL2(interleukin2) 및 TGF-b(beta)로자극하여 CD4Treg를증식시키는단계;를포함하는 CD4면역조절 T 세포(Regulatory T Cell, Treg)의생체외증식방법, 장기이식거부반응억제용조성물및 자가면역질환또는염증성질환의예방또는치료용약학적조성물을제공한다. 본발명의방법은조절 T 세포를대량증식시키고상기증폭된조절 T 세포는탁월한면역억제효과를나타내므로, 동종또는이종간의장기의이식시 수용체(recipient)에서발생하는다양한면역거부반응을극복하는데 효과적으로이용될수 있다.

    물분해용 광촉매 및 이의 제조방법
    5.
    发明公开
    물분해용 광촉매 및 이의 제조방법 有权
    用于水分解的光催化剂及其合成方法

    公开(公告)号:KR1020120011304A

    公开(公告)日:2012-02-07

    申请号:KR1020100073092

    申请日:2010-07-28

    Abstract: PURPOSE: A photo-catalyst for water decomposition and a method for manufacturing the same are provided to decompose pure water and to generate hydrogen by generating electrons and holes from photo-catalysts under light irradiation. CONSTITUTION: A photo-catalyst for water decomposition is represented by chemical formula 1. In chemical formula 1, the M is Nb or Ta. The photo-catalyst carries one metal element selected from Pt, Pd, Ag, Ru, and Ni. The content of the metal element is between 0.1 and 1 weight%. A method for manufacturing the photo-catalyst grinds, mixes, and plasticizes ZnO and a metal oxide. The metal oxide is Nb_2O_5 or Ta_2O_5.

    Abstract translation: 目的:提供用于水分解的光催化剂及其制造方法,以在光照射下从光催化剂中产生电子和空穴来分解纯水并产生氢。 构成:用于水分解的光催化剂由化学式1表示。在化学式1中,M是Nb或Ta。 光催化剂携带一种选自Pt,Pd,Ag,Ru和Ni的金属元素。 金属元素的含量为0.1〜1重量%。 制造光催化剂的方法研磨,混合并增塑ZnO和金属氧化物。 金属氧化物为Nb_2O_5或Ta_2O_5。

    산화 티타늄 나노 튜브 재료 및 그 제조 방법
    7.
    发明公开
    산화 티타늄 나노 튜브 재료 및 그 제조 방법 有权
    氧化钛组成的纳米管材料及其制造方法

    公开(公告)号:KR1020120075957A

    公开(公告)日:2012-07-09

    申请号:KR1020100137887

    申请日:2010-12-29

    Abstract: PURPOSE: A titanium oxide nanotube material and a manufacturing method thereof are provided to improve electro-optical characteristic by arranging surface or direction of a tetragonal crystal system as a preferred direction. CONSTITUTION: A titanium oxide nanotube material has a crystal structure which is aligned in direction of a tetragonal crystal system as a preferred direction. Full width at half maximum of the rocking curve for surface peak of XRD data(004) is 11.1-20.3 degrees. A manufacturing method of the titanium oxide nanotube material comprises the following steps: preparing electrolyte having the moisture content of 1.5-2.5 wt%; dipping a titanium substrate in a vessel in which electrolyte is put; growing the titanium oxide nanotube on the titanium substrate by processing anodizing; desiccating the titanium substrate by washing; and crystallizing the titanium oxide nanotube by heat-treating the desiccated titanium substrate.

    Abstract translation: 目的:提供一种二氧化钛纳米管材料及其制造方法,通过将四方晶系的表面或方向作为优选方向来提高电光特性。 构成:氧化钛纳米管材料具有在四方晶系的方向上作为优选方向排列的晶体结构。 XRD数据(004)表面峰值摇摆曲线半峰全宽为11.1-20.3度。 氧化钛纳米管材料的制造方法包括以下步骤:制备水分含量为1.5-2.5重量%的电解质; 将钛基材浸渍在其中放置电解质的容器中; 通过加工阳极氧化在钛基板上生长钛氧化物纳米管; 通过洗涤干燥钛基材; 并通过对干燥的钛基底进行热处理来使钛氧化物纳米管结晶。

    백색 발광 다이오드에 사용되는 형광체 및 이를 사용한 백색 발광 다이오드
    8.
    发明公开
    백색 발광 다이오드에 사용되는 형광체 및 이를 사용한 백색 발광 다이오드 无效
    用于白光发光二极管的磷光体和使用其的白光发光二极管

    公开(公告)号:KR1020120006872A

    公开(公告)日:2012-01-19

    申请号:KR1020100067580

    申请日:2010-07-13

    CPC classification number: Y02B20/181

    Abstract: PURPOSE: A phosphor for a white light emitting diode, and the white light emitting diode are provided to performing the visible luminescence with a wide luminous band. CONSTITUTION: A phosphor for a white light emitting diode contains the following: a first element selected from lithium, sodium, potassium, rubidium, or cesium; and a second element selected from magnesium, calcium, strontium, or barium. A part of the second element is substituted with a rare earth element. The phosphor emits light by the excitation of light having the peak wavelength of 200-400nm. The white light emitting diode includes a diode(120) radiating ultraviolet rays or blue light; and the phosphonic acid based phosphor(150).

    Abstract translation: 目的:提供用于白色发光二极管的荧光体和白色发光二极管以执行具有较宽发光频带的可见发光。 构成:用于白色发光二极管的磷光体包含以下物质:选自锂,钠,钾,铷或铯的第一元素; 和选自镁,钙,锶或钡的第二元素。 第二元素的一部分被稀土元素代替。 荧光体通过激发峰值波长为200-400nm的光而发光。 白色发光二极管包括辐射紫外线或蓝色光的二极管(120); 和膦酸系荧光体(150)。

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