Abstract:
본발명의어성초추출물은효소처리및 초고압균질화처리를포함하는추출방법으로추출된것으로, 상기추출방법은불용성섬유질성분을가용화시켜추출수율과생리활성이증진되며, 부산물의발생을감소시켜제조단계측면에서도경쟁력을확보할수 있다. 또한, 본발명의어성초추출물을유효성분으로포함하는항산화및 항염증용조성물은항산화기능과염증매개물질인 NO의발생을억제하므로, 항산화및 항염증용화장료조성물및 염증성질환의예방및 치료용약학조성물로서유용하게사용될수 있다.
Abstract:
본발명의어성초추출물은효소처리및 초고압균질화처리를포함하는추출방법으로추출된것으로, 상기추출방법은불용성섬유질성분을가용화시켜추출수율과생리활성이증진되며, 부산물의발생을감소시켜제조단계측면에서도경쟁력을확보할수 있다. 또한, 본발명의어성초추출물을유효성분으로포함하는항산화및 항염증용조성물은항산화기능과염증매개물질인 NO의발생을억제하므로, 항산화및 항염증용화장료조성물및 염증성질환의예방및 치료용약학조성물로서유용하게사용될수 있다.
Abstract:
본 발명은 산약 분말, 산약 분말의 펠릿(pellet), 산약즙 또는 산약 추출물을 포함하는 소화성 궤양 예방용 조성물 및 위산분비 억제용 조성물에 대한 것이며, 추가적으로 그러한 조성물을 포함하는 약제학적 제제 또는 건강기능식품에 대한 것이다. 본 발명에 따른 조성물을 포함하는 약제학적 제제 또는 건강기능식품을 평소에 복용할 경우, 소화성 궤양 발병의 위험성이 현저히 감소될 수 있으며, 소화성 궤양이 발병한 경우라도 조기에 회복될 수 있는 효과를 가진다. 또한 본 발명에 따른 조성물은 위산의 과다분비로 인한 속쓰림 등의 증상 완화에도 탁월한 효능을 가진다.
Abstract:
PURPOSE: A composition containing diosgenin or pharmaceutically acceptable salt thereof is provided to promote proliferation, differentiation, and mineralization of osteoblast. CONSTITUTION: A composition for promoting osteoblast contains diosgenin or pharmaceutically acceptable salt thereof. Diosgenin is isolated from yam. The concentration of the diosgenin is 1-3 uM. A composition for preventing or treating bone metabolism contains diosgenin or pharmaceutically acceptable salt thereof. The bone metabolism is osteoporosis, bone metastatic lesion, rheumatic or degenerative arthritis, periodontal diseases, inflammatory bone absorption or Paget's disease. A food composition for improving bone function contains diogenin or pharmaceutically acceptable salt.
Abstract:
PURPOSE: Novel candied yam slices and a producing method thereof are provided to offer excellent health functionality and long term storage property of the candied yam slices to users. CONSTITUTION: A producing method of novel candied yam slices comprises the following steps: parboiling washed, peeled, and cut yam slices; and soaking the yam slices in a sugar solution, and repeatedly heating and soaking the yam slices before washing and drying. The sugar solution is a mixed composition obtained by using sugar and oligosaccharide, fructose and oligosaccharide, or sugar, oligosaccharide, and honey. The heating and soaking process of the yam includes a step of firstly heating the parboiled yam slices at 95-100 deg C for 2 hours in the 50% sugar solution, a step of soaking the heated yam slices at 60 deg C for 24 hours, a step of secondly heating the yam slices at 95-100 deg C for 2 hours in the 70% sugar solution, and a step of secondly soaking the yam slices at 60 deg C for 24 hours. [Reference numerals] (AA) Washing; (BB) Peeling; (CC) Cutting; (DD) Parboiling; (EE) Blanching temperature 100 deg. C/min; (FF) First heating; (GG) 50% sugar solution/2 hours/98-100 deg. C; (HH) First soaking; (II) Drier/24 hours/60 deg. C; (JJ) Second heating; (KK) 70% sugar solution/2 hours/95-100 deg. C; (LL) Secondly soaking; (MM) Drier/24 hours/60 deg. C; (NN) Washing; (OO) Drying; (PP) Drier/60 deg. C
Abstract:
PURPOSE: A composition containing diosgenin or pharmaceutically acceptable salt thereof is provided to promote proliferation, differentiation, and mineralization of osteoblast. CONSTITUTION: A composition for promoting osteoblast contains diosgenin or pharmaceutically acceptable salt thereof. Diosgenin is isolated from yam. The concentration of the diosgenin is 1-3 uM. A composition for preventing or treating bone metabolism contains diosgenin or pharmaceutically acceptable salt thereof. The bone metabolism is osteoporosis, bone metastatic lesion, rheumatic or degenerative arthritis, periodontal diseases, inflammatory bone absorption or Paget's disease. A food composition for improving bone function contains diogenin or pharmaceutically acceptable salt.
Abstract:
본 발명은 생마의 주아(영여자)로부터 유래된 6,7-디하이드록시-2,4-디메톡시 페난트렌을 유효성분으로 함유하여 다양한 암세포 증식억제 활성을 갖는 약학 조성물 및 건강식품 조성물에 관한 것으로, 본 발명에 따른 6,7-디하이드록시-2,4-디메톡시 페난트렌(6,7-dihydroxy-2,4-dimethoxy phenanthrene)은 암세포주가 아닌 정상 세포 유래의 마우스 MC3T3-E1 (조골 전구세포, 골아세포) 및 지방세포 3T3-L1 (지방 전구세포) 세포주에는 거의 독성을 나타내지 않으면서, 자궁암 세포 (HeLa), 간암세포 (HepG2) 및 대장암 세포 (HCT-116)의 생육을 10~40 ug/mL의 낮은 농도에서 효율적으로 억제할 수 있다. 또한 이러한 암 세포 성장억제는 항암 유전자로 알려진 NAG-1의 활성화를 통해 나타남을 확인하여, 기존의 알려진 파이토케미컬의 암세포 생육 억제 효과 및 암 발생 억제효과를 기대할 수 있다. 6,7-디하이드록시-2,4-디메톡시 페난트렌, 영여자, 암세포 성장 억제 활성
Abstract:
PURPOSE: A composition containing 6,7-dihydroxy-2,4-dimethoxy phenanthrene is provided to efficiently suppress growth of cancer cells at low concentration. CONSTITUTION: A pharmaceutical composition for suppressing cancer cell proliferation contains 6,7-dihydroxy-2,4-dimethoxyphenanthrene as an active ingredient. 6,7-Dihydroxy-2,4-dimethoxyphenanthrene is derived from aerial bulblet. A health food composition for suppressing cancer cell proliferation contains 6,7-dihydroxy-2,4-dimethoxyphenanthrene of chemical formula 1 as an active ingredient.
Abstract:
본 발명은 종래 설탕 또는 올리고당 또는 벌꿀 단독의 당액에 침지처리하여 제조하던 마 정과를 상기 당액을 적절히 혼합조성한 당액을 조제하고 가열 침지처리를 반복한 후 수세 건조하거나 분당 또는 마 분말을 도포하여서 되는 신규한 마 정과 제조방법과 그 제품을 개시하며 상기 본 발명 마 정과 제품은 씹힘성, 보존성, 항산화력 등이 매우 뛰어난 특징이 있다.
Abstract:
PURPOSE: A composition for preventing peptic ulcer and a composition for suppressing gastric secretion are provided to remarkably reduce risk for developing peptic ulcer and to early recover peptide ulcer. CONSTITUTION: A composition for preventing peptic ulcer contains Dioscoreae Rhizoma powder, pellet, juice, or extract as an active ingredient. The extract is prepared using alcohol or a mixture of alcohol and water. A drug and functional food for preventing peptic ulcer contains the composition. The functional food is manufactured in the form of a liquid formulation, candy, gum, paste formulation, and snack. An inhibitor and functional food for suppressing gastric secretion contains the composition.