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公开(公告)号：KR101814175B1
公开(公告)日：2018-01-02
申请号：KR1020170018822
申请日：2017-02-10
Applicant: 전남대학교산학협력단
IPC: A61K36/22 , A61K31/192 , A61K31/352
CPC classification number: A61K36/22 , A61K31/192 , A61K31/352
Abstract: 본발명은옻나무목질부추출물을포함하는어류의항균, 항기생충, 항바이러스및 항산화조성물에관한것으로, 옻나무목질부추출물을포함함으로써, 어류병원성세균, 기생충또는바이러스에의한감염및 감염병을예방또는치료할수 있으며, 면역증강을유도하여어류의폐사를방지할수 있어어류의생산량을증가시킬수 있고, 천연항산화활성물질을추출물내에다량포함하고있어화학약품에의해발생할수 있는독성발생문제및 사료산패를최소화시킬수 있는, 옻나무목질부추출물을포함하는어류의항균, 항기생충, 항바이러스및 항산화조성물에관한것이다.
Abstract translation: 本发明涉及一种鱼的抗菌，包括漆树提取木质部，抗寄生虫药，抗病毒和抗氧化剂组合物，通过包括漆树木质部提取物，并且可以预防或治疗感染和感染性疾病引起的鱼的病原菌，寄生虫或病毒 ，以诱导免疫增强剂可以防止鱼的死亡率，并且可以提高生产的鱼，天然抗氧化剂在这里被多包括在所述提取物中的活性物质，它可以最小化毒性问题和进料可以由化学试剂引起的酸败， 鱼的抗寄生虫，抗病毒和抗氧化剂组成包括漆树verniciflua提取物。
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2.发明授权
公开(公告)号：KR101732022B1
公开(公告)日：2017-05-12
申请号：KR1020150086844
申请日：2015-06-18
Applicant: 전남대학교산학협력단
IPC: A61K36/739 , A61K31/56 , A23K1/16 , A23K1/18
Abstract: 본발명은지유(L.) 추출물또는분획물을유효성분으로포함하는어류병원성바이러스에대한항바이러스조성물에관한것으로, 본발명에따르면, 상기항바이러스조성물은바이러스성출혈성패혈증바이러스(Viral Hemorrhagic Septicemia Virus; VHSV) 및전염성조혈괴저바이러스(Infectious Hematopoietic Necrosis Virus; IHNV)에대하여우수한항바이러스활성을나타낸다.
Abstract translation: 本发明自由丘（L.）涉及含有该提取物或级分作为有效成分的鱼类病原性病毒的抗病毒组合物，根据本发明，病毒性出血性败血症病毒（病毒性出血性败血症病毒的抗病毒组合物; VHSV）和传染性造血器官坏死病毒（IHNV）。
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3.发明公开칠피 추출물 유래의 플라보노이드계 화합물을 함유한 어류병원성 바이러스에 대한 항바이러스 조성물 有权对来自RHUS VERNICIFLUA STOKES的含有FLAVONOID化合物的鱼类致病病毒的抗病毒组合物
公开(公告)号：KR1020120118805A
公开(公告)日：2012-10-29
申请号：KR1020110036411
申请日：2011-04-19
Applicant: 전남대학교산학협력단
Abstract: PURPOSE: An antiviral composition for fish pathogenic viruses which contains flavonoid based compound is provided to show stability of fishery by conquering flavonoid based compound. CONSTITUTION: An antiviral composition for fish pathogenic viruses includes Rhus verniciflua Stokes extract which is obtaind by extracting a Rhus verniciflua Stokes sample with 80% methanol. The antiviral composition for fish pathogenic viruses contains Rhus verniciflua Stokes extract which is obtaind by extracting a Rhus verniciflua Stokes sample with 80% methanol as an active ingredient. An organic solvent is hexane, chloroform, ethyl acetate, and butanol fraction. An antiviral composition for fish pathogenic viruses Rhus verniciflua Stokes extract which is obtaind by extracting a Rhus verniciflua Stokes sample with 80% methanol as an active ingredient.
Abstract translation: 目的：提供含有黄酮类化合物的鱼病原病毒抗病毒组合物，以通过征服类黄酮化合物来显示渔业的稳定性。 构成：鱼病原病毒的抗病毒组合物包括通过提取80％甲醇的Rhus verniciflua Stokes样品获得的Rhus verniciflua Stokes提取物。 鱼病原病毒的抗病毒组合物含有Rhus verniciflua Stokes提取物，其通过以80％甲醇作为活性成分提取Rhus verniciflua Stokes样品而获得。 有机溶剂为己烷，氯仿，乙酸乙酯和丁醇级分。 一种用于鱼病原病毒的抗病毒组合物通过以80％甲醇作为活性成分提取Rhus verniciflua Stokes样品获得的斯氏杆菌提取物。
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4.发明授权모로우붉은실 추출물 또는 이로부터 분리되거나 합성된 화합물을 포함하는 항스쿠티카충 조성물 有权含有Polysiphonia morrowii Harvey提取物的抗scuticociliatic组合物，或合成或分离的化合物
公开(公告)号：KR101149382B1
公开(公告)日：2012-06-01
申请号：KR1020100004467
申请日：2010-01-18
Applicant: 전남대학교산학협력단
Abstract: 본발명은모로우붉은실(Harvey) 추출물또는이의비극성용매가용분획물또는이로부터분리한화합물또는이의유도체를함유하는어류의스쿠티카감염예방, 치료또는억제용조성물에관한것으로, 본발명에따른모로우붉은실추출물또는이의분획물들은유의적인항스쿠티카활성을나타내며, 상기분획물로부터분리한화합물및 이의유도체들은스쿠티카충에의한어류의폐사를유의적으로경감시키는효과가있다.
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公开(公告)号：KR101833288B1
公开(公告)日：2018-02-28
申请号：KR1020160113689
申请日：2016-09-05
Applicant: 전남대학교산학협력단
IPC: A61K36/28 , A61K31/352 , A23K10/30 , A23K20/121
CPC classification number: A61K36/28 , A23K10/30 , A23K20/121 , A61K31/352
Abstract: 본발명은엉겅퀴추출물, 이의분획물또는이로부터분리한화합물을유효성분으로함유하는어류용항바이러스조성물에관한것이다. 본발명에따른엉겅퀴추출물, 이의분획물또는이로부터분리한화합물을유효성분으로함유하는어류용항바이러스조성물은폐사율에영향을주는바이러스에대하여항바이러스효과가있고, 상기조성물을복강주사하거나경구투여하거나수조투여함으로써양식어류의폐사율에큰 영향을미치는바이러스에의한질환의예방또는치료가가능할뿐만아니라, 이에의해어류양식산업의원가절감과부가가치증대에크게기여할수 있다.
Abstract translation: 本发明涉及含有蓟提取物，其部分或从中分离的化合物作为有效成分的鱼类病毒组合物。 水飞蓟提取物，鱼永航病毒组合物可以根据本发明的具有对影响死亡率病毒，腹膜内注射或口服给药，或罐用于容纳从其馏分或作为活性成分的分离的化合物，组合物的抗病毒效果 有可能预防或治疗由对病鱼死亡率影响很大的病毒引起的疾病，从而有助于鱼类养殖业的成本降低和附加值的提高。
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Patent Agency Ranking6.发明授权칠피 추출물 유래의 플라보노이드계 화합물을 함유한 어류병원성 바이러스에 대한 항바이러스 조성물 有权包含来自紫草（Rhus verniciflua Stokes）的类黄酮化合物的针对鱼病原体病毒的抗病毒组合物
公开(公告)号：KR101431877B1
公开(公告)日：2014-08-25
申请号：KR1020110036411
申请日：2011-04-19
Applicant: 전남대학교산학협력단
Abstract: 본 발명은 칠피의 메탄올 추출물과 이의 다양한 유기용매 추출분획물로부터 어류병원성 항바이러스 활성 플라보노이드계 화합물을 분리·정제하고, 상기 칠피 추출물 및 유기용매 추출분획으로부터 분리정제한 플라보노이드계 화합물의 어류병원성 항바이러스 활성을 개시한다.
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公开(公告)号：KR1020110084744A
公开(公告)日：2011-07-26
申请号：KR1020100004467
申请日：2010-01-18
Applicant: 전남대학교산학협력단
Abstract: PURPOSE: An anti-scuticociliatic composition containing Polysiphonia morrowii Harvey extract or compounds isolated from the extract is provided to reduce fish death by scuticociliates. CONSTITUTION: An anti-scuticociliatic composition contains Polysiphonia morrowii Harvey extract or compounds isolated from the extract as an active ingredient. The extract is isolated by non-polarity solvent. The non-polarity solvent is selected from the group consisting of MeOH, n-hexane, or CH_2Cl_2.
Abstract translation: 目的：提供含有Polysiphonia morrowii Harvey提取物或从提取物中分离的化合物的抗小鼠鳞状细胞组合物，以减少scutococates对鱼的死亡。 构成：抗小鼠鳞状细胞组合物含有Polysiphonia morrowii Harvey提取物或从提取物中分离的化合物作为活性成分。 提取物通过非极性溶剂分离。 非极性溶剂选自MeOH，正己烷或CH 2 Cl 2。
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8.发明公开칠피 추출물 또는 이로부터 분리되거나 합성된 갈레이트 유도체를 포함하는 항스쿠티카충 조성물 有权含有RHUS VERNICIFLUA BARK提取物或合成或分离的GALLATE衍生物的抗SCOTICOCILIATIC组合物
公开(公告)号：KR1020110042613A
公开(公告)日：2011-04-27
申请号：KR1020090099362
申请日：2009-10-19
Applicant: 전남대학교산학협력단
IPC: A61K36/22 , A61P33/00 , A61K31/216
CPC classification number: A61K31/216 , A61K36/22
Abstract: PURPOSE: A composition containing Rhus verniciflua bark extract or galate derivative isolated from the same are provided to ensure significant anti-scuticociliatida activity. CONSTITUTION: A composition for preventing or treating scuticociliatida infection of fishes contains Rhus verniciflua bark extract as an active ingredient. The Rhus verniciflua bark extract is isolated using non-polar solvent extract. The non-polar solvent is n-hexane, CHCl3, EtOAc, n-BuOH, or H_2O. A composition for preventing or treating scuticociliatida infection contains Rhus verniciflua bark extract-derived methyl galate of chemical formula 1 or a galate derivative of chemical formula 2 as an active ingredient. The galate derivative is gallic acid, ethyl galate, propyl galate, butyl galate, or isoamyl galate.
Abstract translation: 目的：提供含有从其分离的玫瑰提取物或galate衍生物的组合物，以确保显着的抗scuticociliatida活性。 构成：用于预防或治疗鱼类鳞状真菌感染的组合物含有紫荆树皮提取物作为活性成分。 使用非极性溶剂提取物分离紫薇树皮提取物。 非极性溶剂是正己烷，CHCl 3，EtOAc，n-BuOH或H 2 O。 用于预防或治疗小菜蛾感染的组合物含有化学式1的德文蛇皮提取物衍生的甲基半乳糖酸盐或化学式2的半乳酸衍生物作为活性成分。 加仑酸衍生物是没食子酸，乙酸乙酯，加合丙酸乙酯，加仑酸丁酯或异戊酸镓酸盐。
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9.发明公开친환경어류양식을 위한 어류 면역증강 및 어류 병원성세균에 대한 감염 예방, 치료 또는 억제용 칠피 추출물,그의 분획물, 이로부터 분리한 갈레이트 화합물 및 이를함유한 조성물 有权提取物，其分离物，分离的凝胶化合物和含有它们的组合物，用于增强鱼类免疫力，预防和治疗鱼致病性细菌感染性感染，或抑制鱼类致病菌的增殖
公开(公告)号：KR1020080084355A
公开(公告)日：2008-09-19
申请号：KR1020070026002
申请日：2007-03-16
Applicant: 전남대학교산학협력단
Abstract: A composition comprising the extract of Rhus verniciflua bark is provided to inhibit proliferation of fish pathogenic bacteria, and enhance fish immunity by increasing activity of lysozyme in blood, so that the composition is useful for prevention and treatment of fish pathogenic bacteria-induced infection. A composition for prevention and treatment of fish pathogenic bacteria-induced infection comprises the extract of Rhus verniciflua bark which is prepared by suspending Rhus verniciflua bark in distilled water and extracting the suspension of Rhus verniciflua bark with non-polar organic solvent selected from n-hexane, chloroform, ethylacetate and n-butanol, or methyl-3,4,5-trihydroxybenzoate represented by the formula(I) isolated from the Rhus verniciflua bark extract, wherein the fish pathogenic bacteria include Edwardsiella tarda, Vibrio anguillarum, Flexibacter maritimus and Photobacterium damselae subsp. piscicida.
Abstract translation: 提供一种包含紫薇提取物的组合物以抑制鱼病原菌的增殖，并通过增加血液中溶菌酶的活性来提高鱼的免疫力，从而使该组合物可用于预防和治疗鱼病原菌诱导的感染。 用于预防和治疗鱼类致病菌诱导感染的组合物包括通过将紫草（Rhus verniciflua）树皮悬浮在蒸馏水中而提取的Rhus verniciflua树皮的提取物，并用选自正己烷的非极性有机溶剂萃取Rhus verniciflua树皮的悬浮液 ，氯仿，乙酸乙酯和正丁醇，或由Rhus verniciflua树皮提取物分离的式（I）表示的甲基-3,4,5-三羟基苯甲酸酯，其中鱼病原菌包括枸杞子，鳗弧菌，马贝菌和光杆菌 dam ae子 piscicida。
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公开(公告)号：KR102025884B1
公开(公告)日：2019-09-26
申请号：KR1020190036662
申请日：2019-03-29
Applicant: 전남대학교산학협력단
IPC: A61K36/22 , A61K31/192 , A61K31/352
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