Abstract:
본 발명은 생체 내에서 암 조직에 대하여 특이적으로 타겟팅 될 수 있는 박테리아 기반의 마이크로비드를 제공하기 위하여, 바이오틴(biotin)이 표면에 결합된 갖는 박테리아와 스트렙타비딘(streptavidin)이 표면에 코팅되고, 약물이 물리적으로 봉입된 마이크로비드를 포함하는 암 조직에 대한 약물운반체을 제공한다.
Abstract:
The present invention provides a drug delivery agent for cancer tissues containing microbeads in which bacteria with biotin combined to the surface and streptavidin are coated on the surface of the microbeads and drugs are physically inserted, for providing bacterium based microbeads which is capable of specifically targeting the cancer tissues in a living body.
Abstract:
PURPOSE: A method for manufacturing a super-hydrophobic sheet is provided to produce a structure which includes a protrusion having a super-hydrophobic effect by controlling hardening time and number of a photo-resist. CONSTITUTION: The surface of a silicon wafer is cleaned(S10). A photo-resist is coated on the upper side of the silicon wafer by using a spin coater(S20). The silicon wafer in which the photo-resist is coated is softly baked by using an oven. A structure is exposed by using a mask aligner(S30). The structure is developed by using a photo-resist developer(S40). A PDMS(Polydimethylsiloxane) molding process is executed to the upper side of the structure(S50). The photo-resist is eliminated by using acetone(S60).