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公开(公告)号：WO2011049273A1
公开(公告)日：2011-04-28
申请号：PCT/KR2010/000501
申请日：2010-01-28
IPC: A61K8/97 , A61K8/92 , A61Q19/02 , A61K36/185
CPC classification number: A61Q19/02 , A61K8/922 , A61K9/0019 , A61K9/06 , A61K36/185 , A61K47/02 , A61K2800/782
Abstract: 본 발명은 달맞이꽃 종자유 비누화물을 유효성분으로 함유하는 피부 미백 조성물을 제공한다. 본 발명의 달맞이꽃 종자유 비누화물은 멜라닌 색소 생성에 필수적으로 관여하는 타이로시나아제 유전자와 멜라닌 색소 형성에 관련된 Trp1, Trp2, 및 MITF 유전자의 발현을 억제하여 뛰어난 색소 침착 저해 효과를 나타내므로 피부 미백에 유용하게 사용될 수 있다.
Abstract translation: 本发明涉及含有皂化的月见草籽油作为活性成分的皮肤美白组合物。 本发明的皂化的月见草籽油抑制酪氨酸酶基因表达，其对于黑色素产生是必需的，抑制与黑色素产生相关的Trp1，Trp2和MITF基因表达，在抑制色素沉着方面表现出优异的效果，并且可以有效地使用 用于美白皮肤。
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2.发明公开감송향 추출물을 유효성분으로 포함하는 제１형 당뇨병 예방 및 치료용 조성물과 이를 포함하는 건강식품 无效包含NARDOSTACHYS JATAMANSI提取物的组合物，用于预防和治疗胰岛素依赖性糖尿病，包括其中的食物
公开(公告)号：KR1020110098500A
公开(公告)日：2011-09-01
申请号：KR1020100018147
申请日：2010-02-26
Applicant: 전북대학교산학협력단
Abstract: 본 발명은 감송향 추출물을 유효성분으로 포함하는 제1형 당뇨병 예방 및 치료용 조성물, 및 이를 포함하는 건강식품에 관한 것이다.
상기 감송향 추출물을 제1형 당뇨병 질환에 이용함으로서, 지속적인 인슐린 투여가 필요한 제1형 당뇨병을 예방 또는 치료할 수 있다는 장점과, 감송향과 같은 천연물질을 사용함으로써, 부작용 우려를 피할 수 있다. 그러므로, 제1형 당뇨병을 예방 또는 치료함으로써, 환자의 건강에 기여할 수 있으며, 당뇨병과 관련된 산업에 유용하게 사용될 수 있다.-
公开(公告)号：KR1020100111260A
公开(公告)日：2010-10-14
申请号：KR1020100081891
申请日：2010-08-24
Applicant: 전북대학교산학협력단
Abstract: PURPOSE: A therapeutic agent for anti-diabetes containing Fructus Xanthii extract is provided to suppress NF-kappa B activation and to protect cell by nitric oxide reduction. CONSTITUTION: A pharmaceutical composition for suppressing islet break after pancreas or pancreatic duct transplantation surgery contains 0.1-99 weight% of Fructus Xanthii extract. The composition further contains carrier, excipient or diluents. The composition is used in the form of powder, tablet, capsule, suspension, syrup, dry syrup or aerosol, suppository, or external use.
Abstract translation: 目的：提供含有枸杞子提取物的抗糖尿病治疗剂，以抑制NF-κB活化，并通过一氧化氮减少来保护细胞。 构成：胰腺或胰管移植手术后抑制胰岛破裂的药物组合物含有0.1-99重量％的苦参提取物。 组合物还含有载体，赋形剂或稀释剂。 该组合物以粉末，片剂，胶囊，悬浮液，糖浆，干糖浆或气雾剂，栓剂或外用形式使用。
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公开(公告)号：KR100962435B1
公开(公告)日：2010-06-14
申请号：KR1020080034896
申请日：2008-04-15
Applicant: 전북대학교산학협력단
IPC: A61K36/904 , A61P3/04
Abstract: 본 발명은 물을 이용한 비해 (
Rhizoma
dioscoreae
tokoronis ) 추출물을 유효성분으로 하는 항비만 조성물에 관한 것으로, 고지방식이에 의한 체중증가를 억제할 수 있다. 구체적으로는 고지방 식이군에 비해 추출물을 투여한 결과 혈중 triglyceride, LDL-cholesterol, total cholesterol을 낮추고, 반대로 심혈관 질환을 억제하는 HDL-cholesterol 수치는 높임으로써 항비만 치료제로서 제공할 수 있다.
비해 추출물, 비만, 고지방식이-
5.发明授权옻나무로부터 분리된 설퍼레틴을 유효성분으로 포함하는 제１형 당뇨병 예방 및 치료용 조성물 및 이를 포함하는 건강식품 有权组合物，其包含用于预防和治疗胰岛素依赖性糖尿病的来自Rhus verniciflura的分离的硫代嘌呤，其组合物
公开(公告)号：KR101159442B1
公开(公告)日：2012-06-22
申请号：KR1020100038667
申请日：2010-04-26
Applicant: 전북대학교산학협력단
Abstract: PURPOSE: A composition containing sulfuretin is provided to prevent or treat type 1 diabetes and to prevent side effects of the diabetes. CONSTITUTION: A composition for preventing and treating type 1 diabetes contains sulfuretin, isolated from Rhus verniciflura, as an active ingredient. A NF-kappaB inhibitor contains sulfuretin, isolated and purified from Rhus verniciflura, as an active ingredient. An iNOS expression inhibitor contains sulfurein as an active ingredient. A health food for preventing diabetes contains sulfuretin as an active ingredient. The composition additionally contains pharmaceutically or nutritionally acceptable carrier, excipient, diluent, or accessory ingredients.
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Patent Agency Ranking
公开(公告)号：KR1020120029528A
公开(公告)日：2012-03-27
申请号：KR1020100091362
申请日：2010-09-17
Applicant: 전북대학교산학협력단
Abstract: PURPOSE: A composition containing sulfuretin isolated and purified Rhus verniciflua is provided to reduce airway inflammatory response and to treat asthma. CONSTITUTION: A composition for preventing and treating bronchial asthma contains sulfuretin isolated from Rhus verniciflua as an active ingredient. An inhibitor of cytokine immune response contains sulfuretin as an active ingredient. An NF-kappaB activity inhibitor contains sulfuretin as an active ingredient. A composition for preventing and treating airway hyperreactivity contains sulfuretin as an active ingredient.
Abstract translation: 目的：提供一种分离纯化的硫脲素的组合物，以减少气道炎症反应和治疗哮喘。 构成：用于预防和治疗支气管哮喘的组合物含有从Rhus verniciflua中分离的硫脲素作为活性成分。 细胞因子免疫应答抑制剂含有硫脲素作为活性成分。 NF-κB活性抑制剂含有硫脲素作为活性成分。 用于预防和治疗气道高反应性的组合物含有硫化铜作为活性成分。
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公开(公告)号：KR1020110042886A
公开(公告)日：2011-04-27
申请号：KR1020090099750
申请日：2009-10-20
Applicant: 전북대학교산학협력단
IPC: A61K8/97 , A61K8/92 , A61Q19/02 , A61K36/185
CPC classification number: A61Q19/02 , A61K8/922 , A61K9/0019 , A61K9/06 , A61K36/185 , A61K47/02 , A61K2800/782
Abstract: PURPOSE: A skin whitening composition containing Oenothera odorata seed oil saponificated compounds is provided to suppress the expression of Trp1, Trp2, and MITF gene. CONSTITUTION: A skin whitening cosmetic composition contains Oenothera odorata seed oil saponificated compounds. The Oenothera odorata seed oil saponificated compound is obtained using alkali metal hydroxide of NaOH, LiOH, or KOH. The composition is manufactured in the form of skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, massage cream, moisture cream, essence, nutrition essence, pack, soap, shampoo, cleansing foam, and cleansing cream. A pharmaceutical composition for preventing and treating pigmentation contains Oenothera odorata seed oil saponificated compounds as an active ingredient. The composition is manufactured in the form of cream, gel, patch, spray, ointment, lotion, liniment, pasta, or cataplasma.
Abstract translation: 目的：提供含有欧奈氏菌子油皂化合物的皮肤美白组合物，以抑制Trp1，Trp2和MITF基因的表达。 构成：皮肤美白化妆品组合物含有欧奈氏odor子籽油皂化化合物。 使用NaOH，LiOH或KOH的碱金属氢氧化物，得到亚麻子油皂化皂化合物。 该组合物以皮肤洗剂，皮肤柔软剂，皮肤调色剂，收敛剂，乳液，乳液，湿润乳液，按摩霜，防湿霜，精华液，营养精华，包装，肥皂，洗发剂，清洁泡沫和清洁霜的形式制成。 。 用于预防和治疗色素沉着的药物组合物含有作为活性成分的欧烯类气味种子油皂化化合物。 该组合物以奶油，凝胶，贴剂，喷雾剂，软膏剂，洗剂，搽剂，面食或粘膜的形式制备。
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8.发明公开옻나무로부터 분리된 설퍼레틴을 유효성분으로 포함하는 제１형 당뇨병 예방 및 치료용 조성물 및 이를 포함하는 건강식품 有权包含来自RHUS VERNICIFLURA的分离的硫蛋白的组合物，用于预防和治疗胰岛素依赖性糖尿病，包括其中的食物
公开(公告)号：KR1020110119141A
公开(公告)日：2011-11-02
申请号：KR1020100038667
申请日：2010-04-26
Applicant: 전북대학교산학협력단
Abstract: PURPOSE: A composition containing sulfuretin is provided to prevent or treat type 1 diabetes and to prevent side effects of the diabetes. CONSTITUTION: A composition for preventing and treating type 1 diabetes contains sulfuretin, isolated from Rhus verniciflura, as an active ingredient. A NF-kappaB inhibitor contains sulfuretin, isolated and purified from Rhus verniciflura, as an active ingredient. An iNOS expression inhibitor contains sulfurein as an active ingredient. A health food for preventing diabetes contains sulfuretin as an active ingredient. The composition additionally contains pharmaceutically or nutritionally acceptable carrier, excipient, diluent, or accessory ingredients.
Abstract translation: 目的：提供含有硫脲锡的组合物以预防或治疗1型糖尿病并预防糖尿病的副作用。 构成：用于预防和治疗1型糖尿病的组合物含有作为活性成分的从Rhus verniciflura分离的硫脲素。 NF-κB抑制剂含有从Rhus verniciflura分离和纯化的硫化铜作为活性成分。 iNOS表达抑制剂含有硫脲素作为活性成分。 用于预防糖尿病的保健食品含有硫脲素作为活性成分。 该组合物还含有药学上或营养上可接受的载体，赋形剂，稀释剂或辅助成分。
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公开(公告)号：KR1020110029962A
公开(公告)日：2011-03-23
申请号：KR1020090087850
申请日：2009-09-17
Applicant: 전북대학교산학협력단
Abstract: PURPOSE: A composition containing a saponification product of sunflower oil is provided to prevent and treat pigmentary disorder without side effects. CONSTITUTION: A cosmetic composition for skin whitening contains a saponification product of sunflower oil as an active ingredient. The cosmetic composition is manufactured in the form of skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, massage cream, moisture cream, hand cream, essence, pack, soap, shampoo, cleansing foam, or eye shadow. A composition for preventing and treating pigmentary disorder contains 0.001-99.9% of saponification product of sunflower oil. The composition is manufactured in the form of gel, cream, patch, spray, ointment, plaster, lotion, or cataplasma.
Abstract translation: 目的：提供含有向日葵油皂化产物的组合物，以预防和治疗无副作用的色素障碍。 构成：用于皮肤美白的化妆品组合物含有向日葵油作为活性成分的皂化产物。 化妆品组合物以皮肤洗剂，皮肤柔肤剂，皮肤调色剂，收敛剂，洗剂，乳液，按摩霜，防湿霜，护手霜，香精，包装，肥皂，洗发剂，清洁泡沫或眼影的形式制成。 用于预防和治疗色素障碍的组合物含有向日葵油的皂化产物的0.001-99.9％。 组合物以凝胶，霜剂，贴剂，喷雾剂，软膏剂，石膏剂，洗剂或粘膜的形式制备。
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公开(公告)号：KR1020090109443A
公开(公告)日：2009-10-20
申请号：KR1020080034896
申请日：2008-04-15
Applicant: 전북대학교산학협력단
IPC: A61K36/904 , A61P3/04
Abstract: PURPOSE: An anti-obesity composition containing Diosorea tokora makino extract using water is provided to lower triglyceride, LDL-cholesterol, and total cholesterol in blood. CONSTITUTION: An anti-obesity comosition contains Diosorea tokora makino extract as an effective ingredient. The Diosorea tokora makino extract is obtained by adding water to Diosorea tokora makino, heating 5-100°C for 15 minutes to 12 hours, centrifuging at 2,000-3,000 rpm for 10 to 20 minutes, extracting for 30 minutes to three hours, and decompress-drying the extract to obtain powder.
Abstract translation: 目的：提供使用水的含有Diosorea tokora makino提取物的抗肥胖组合物，以降低血液中的甘油三酯，LDL-胆固醇和总胆固醇。 构成：抗肥胖组合含有薯contains皂甙作为有效成分。 通过向薯to蓉加入水，通过加热5-100℃15分钟至12小时，以2,000-3,000rpm离心10〜20分钟，提取30分钟〜3小时，得到Diosorea tokora makino提取物， 将提取物干燥以获得粉末。
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