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公开(公告)号:KR1020090032094A
公开(公告)日:2009-03-31
申请号:KR1020097001236
申请日:2007-07-16
Applicant: 포항공과대학교 산학협력단
CPC classification number: A61K38/1808
Abstract: A method for controlling a blood-sugar numerical value is provided to process an epidermal growth factor within a short time to promote insulin secretion glucose-independently through Ca2+ inflow and PLD2- dependent mechanism. A pharmaceutical composition for preventing and curing diabetes comprises an epidermal growth factor and a pharmaceutically allowable carrier. The epidermal growth factor promotes insulin secretion in a pancreas beta-cell in a glucose-independent way. The epidermal growth factor promotes insulin secretion in the pancreas beta-cell through Ca2+ inflow and PLP2 activity. The epidermal growth factor indicates human epidermal growth factor.
Abstract translation: 提供一种控制血糖值的方法,以在短时间内处理表皮生长因子,通过Ca2 +流入和PLD2-依赖机制独立地促进胰岛素分泌葡萄糖。 用于预防和治疗糖尿病的药物组合物包括表皮生长因子和药学上可允许的载体。 表皮生长因子以葡萄糖非依赖的方式促进胰腺β细胞中的胰岛素分泌。 表皮生长因子通过Ca2 +流入和PLP2活性促进胰腺β细胞中的胰岛素分泌。 表皮生长因子表示人表皮生长因子。
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