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公开(公告)号：KR101069898B1
公开(公告)日：2011-10-05
申请号：KR1020087006105
申请日：2006-08-14
Applicant: 주식회사 포스코 , 포항공과대학교 산학협력단
CPC classification number: C12Q1/6816 , G01Q60/42 , C12Q2565/601
Abstract: 본발명은원자현미경(atomic force microscopy, ATM)용캔틸레버(cantilever)에관한것이다. 상기캔틸레버는고정말단과비고정말단을가진캔틸레버본체, 덴드론(dendron)의분지된부위에있는다수의말단과결합하고덴드론에의해화학적으로변형된표면부위를가진비고정말단, 및관능기화된덴드론의선형부위의말단을포함한다.
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Patent Agency Ranking
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公开(公告)号：KR1020080052587A
公开(公告)日：2008-06-11
申请号：KR1020087006105
申请日：2006-08-14
Applicant: 주식회사 포스코 , 포항공과대학교 산학협력단
CPC classification number: C12Q1/6816 , G01Q60/42 , B82Y35/00 , C12Q2565/601 , G01N33/50
Abstract: Biomolecule interaction using an atomic force microscope is provided to analyze ligand-receptor interaction by fixing a ligand at the tip of the atomic force microscope using dendron. A cantilever for an atomic force microscope comprises a main body with a fixed end and a free end. The free end has a surface chemically deformed by dendron. The ends located on a basin of the dendron are coupled to the deformed surface. The end of linear portion of the dendron has become a functional group.
Abstract translation: 提供使用原子力显微镜的生物分子相互作用，通过使用树枝状结构在原子力显微镜的尖端固定配体来分析配体 - 受体相互作用。 原子力显微镜的悬臂包括具有固定端和自由端的主体。 自由端具有通过树枝状化学变形的表面。 位于树突的盆地上的端部与变形的表面相连。 树突的直线部分的末端已经成为一个官能团。
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公开(公告)号：KR1020110028565A
公开(公告)日：2011-03-18
申请号：KR1020117005477
申请日：2006-08-14
Applicant: 주식회사 포스코 , 포항공과대학교 산학협력단
CPC classification number: C12Q1/6816 , G01Q60/42 , G01Q60/24 , C12Q1/6834 , C12Q2565/601
Abstract: PURPOSE: Biomolecule interaction using an atomic force microscopy is provided to obtain a cantilever with fixed end and free end, the surface of which is chemically transformed due to dendrons. CONSTITUTION: A cantilever(50) includes fixed end and free end. The surface of the free end is chemically transformed due to the combination with respect to ends in the branched part of dendrons. The ends in the linear part of the dendrons are combined by probe nucleotide. A target nucleotide is fixed to a substrate(20). A modulator modulates the relative position and direction of the cantilever and the substrate. A detector measures a physical variable related to the combination of the probe and target nucleotides.
Abstract translation: 目的：提供使用原子力显微镜的生物分子相互作用，以获得具有固定端和自由端的悬臂，其表面由于树枝状化学而被化学转化。 构成：悬臂（50）包括固定端和自由端。 由于相对于树枝状突起的分支部分中的末端的组合，自由端的表面被化学转化。 通过探针核苷酸将树突状物的线性部分的末端组合。 靶核苷酸被固定到基底（20）上。 调制器调制悬臂和基板的相对位置和方向。 检测器测量与探针和靶核苷酸的组合相关的物理变量。
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公开(公告)号：KR1020090032094A
公开(公告)日：2009-03-31
申请号：KR1020097001236
申请日：2007-07-16
Applicant: 포항공과대학교 산학협력단
CPC classification number: A61K38/1808
Abstract: A method for controlling a blood-sugar numerical value is provided to process an epidermal growth factor within a short time to promote insulin secretion glucose-independently through Ca2+ inflow and PLD2- dependent mechanism. A pharmaceutical composition for preventing and curing diabetes comprises an epidermal growth factor and a pharmaceutically allowable carrier. The epidermal growth factor promotes insulin secretion in a pancreas beta-cell in a glucose-independent way. The epidermal growth factor promotes insulin secretion in the pancreas beta-cell through Ca2+ inflow and PLP2 activity. The epidermal growth factor indicates human epidermal growth factor.
Abstract translation: 提供一种控制血糖值的方法，以在短时间内处理表皮生长因子，通过Ca2 +流入和PLD2-依赖机制独立地促进胰岛素分泌葡萄糖。 用于预防和治疗糖尿病的药物组合物包括表皮生长因子和药学上可允许的载体。 表皮生长因子以葡萄糖非依赖的方式促进胰腺β细胞中的胰岛素分泌。 表皮生长因子通过Ca2 +流入和PLP2活性促进胰腺β细胞中的胰岛素分泌。 表皮生长因子表示人表皮生长因子。
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公开(公告)号：KR101069899B1
公开(公告)日：2011-10-05
申请号：KR1020117005477
申请日：2006-08-14
Applicant: 주식회사 포스코 , 포항공과대학교 산학협력단
CPC classification number: C12Q1/6816 , G01Q60/42 , C12Q2565/601
Abstract: 본발명은원자현미경(atomic force microscopy, ATM)용캔틸레버(cantilever)에관한것이다. 상기캔틸레버는고정말단과비고정말단을가진캔틸레버본체, 덴드론(dendron)의분지된부위에있는다수의말단과결합하고덴드론에의해화학적으로변형된표면부위를가진비고정말단, 및관능기화된덴드론의선형부위의말단을포함한다.
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