公开(公告)号：KR1020120086496A

公开(公告)日：2012-08-03

申请号：KR1020110007755

申请日：2011-01-26

Applicant: 한국식품연구원

Inventor： 최인욱 ,  박용곤 ,  김윤숙 ,  박호용 ,  최희돈 ,  최상윤 ,  정순희 ,  엄효진

IPC: C07D311/62 ,  A61K31/353 ,  A61P35/00

Abstract: PURPOSE: A composition containing a catechin-acetaldehyde condensation product and a method for preparing the same are provided to improve antioxidation and anti-cancer effects. CONSTITUTION: A method for preparing a condensation composition of chemical formula 1 comprises a step of adding catechin and acetaldehyde to a solvent in a molar ratio of 1:1-1:5. The method additionally comprises dialysis of a resultant using a dialyzer having 1.0kDa of molecular weight cut-off to remove unreacted products. A composition for anti-cancer and antioxidation contains the condensation composition.

Abstract translation: 目的：提供含有儿茶素 - 乙醛缩合产物的组合物及其制备方法，以改善抗氧化和抗癌作用。 构成：制备化学式1的缩合组合物的方法包括以1：1-1：5的摩尔比将儿茶素和乙醛加入到溶剂中的步骤。 该方法另外包括使用具有1.0kDa分子量截止值的透析器透析所得物以除去未反应的产物。 用于抗癌和抗氧化的组合物含有缩合组合物。