이콜라이 O157:H7균주에 대한 RNA 앱타머
    4.
    发明公开
    이콜라이 O157:H7균주에 대한 RNA 앱타머 无效
    用于E.COLI O157:H7的RNA APTAMERS

    公开(公告)号:KR1020130063012A

    公开(公告)日:2013-06-13

    申请号:KR1020137007651

    申请日:2011-12-14

    Abstract: PURPOSE: An RNA aptamer is provided to detect E.coli O157:H7 by specifically binding to E.coli O157:H7, to prevent E.coli O157:H7, and to prevent food spoilage. CONSTITUTION: An RNA aptamer has a base sequence selected from a group consisting of sequence numbers 1-4, which specifically binds to E.coli O157:H7. Urecil(U) and cytosine(C) of sequence number 1 or 2 have 2' hydroxyl group which is substituted with a fluorine group. A biosensor for detecting E.coli O157:H7 contains the RNA aptamer. A pharmaceutical composition for preventing or treating diseases selected from a group consisting of food poisoning, hemolytic uremic syndrome(HUS), and hemolytic anemia contains the RNA aptamer. A food additive composition contains the RNA aptamer.

    Abstract translation: 目的:提供RNA适体以通过特异性结合大肠杆菌O157:H7来检测大肠杆菌O157:H7,以防止大肠杆菌O157:H7,并防止食物变质。 构成:RNA适体具有选自序列号1-4的碱基序列,其特异性结合大肠杆菌O157:H7。 序列号1或2的Urecil(U)和胞嘧啶(C)具有被氟基团取代的2'羟基。 用于检测大肠杆菌O157:H7的生物传感器含有RNA适体。 用于预防或治疗选自食物中毒,溶血性尿毒综合征(HUS)和溶血性贫血的疾病的药物组合物含有RNA适体。 食品添加剂组合物含有RNA适体。

    포도상구균의 테이코산에 대한 RNA 앱타머
    5.
    发明公开
    포도상구균의 테이코산에 대한 RNA 앱타머 无效
    。。。。。。。。。。。。。。。。。。。。

    公开(公告)号:KR1020120068235A

    公开(公告)日:2012-06-27

    申请号:KR1020100129767

    申请日:2010-12-17

    Abstract: PURPOSE: An RNA aptamer to teichoic acid of staphylococcus is provided to detect Staphylococcus and to prevent and treat staphylococcal pneumonia, sepsis, osteomyelitis, staphylococcus lymphocytic enteritis, sitotoxism, SSSS(staphylococcal scalded skin syndrome) and TSS(toxic shock syndrome). CONSTITUTION: An RNA aptamer which specifically binds to teichoic acid of staphylococcus aureus has a base of sequence number 1. A biosensor for detecting staphylococcus aureus contains the RNA aptamer. A pharmaceutical composition for preventing or treating pneumonia, sepsis, osteomyelitis, staphylococcus lymphocytic enteritis, or sitotoxism contains the RNA aptamer. A food additive composition contains the RNA aptamer.

    Abstract translation: 目的:提供葡萄球菌磷酸的RNA适体,以检测葡萄球菌,预防和治疗葡萄球菌性肺炎,败血症,骨髓炎,葡萄球菌淋巴细胞性肠炎,静脉炎,SSSS(葡萄球菌性烫伤皮肤综合征)和TSS(中毒性休克综合征)。 构成:特异性结合金黄色葡萄球菌的磷壁酸的RNA适体具有序列号1的碱基。用于检测金黄色葡萄球菌的生物传感器含有RNA适体。 用于预防或治疗肺炎,败血症,骨髓炎,葡萄球菌淋巴细胞性肠炎或sitotoxism的药物组合物含有RNA适体。 食品添加剂组合物含有RNA适体。

    이콜라이 O157:H7균주에 대한 RNA 앱타머
    7.
    发明公开
    이콜라이 O157:H7균주에 대한 RNA 앱타머 无效
    用于E.COLI O157:H7的RNA APTAMERS

    公开(公告)号:KR1020120068233A

    公开(公告)日:2012-06-27

    申请号:KR1020100129765

    申请日:2010-12-17

    Abstract: PURPOSE: An RNA aptamer to E.coli O157:H7 strain is provided to specifically bind to the strain and to prevent food decay. CONSTITUTION: An RNA aptamer which specifically binds to E.coli O157:H7 has a base selected from sequence numbers 1-4. Uracil(U) and cytosine of sequence numbers 1-4 are substituted with fluorine at 2' hydroxyl group. A biosensor for detecting E.coli O157:H7 contains the RNA aptamer. A pharmaceutical composition for preventing or treating food poisoning, hemolytic uremic syndrome or hemolytic anemia contains the composition. A food additive composition contains the RNA aptamer.

    Abstract translation: 目的:提供大肠杆菌O157:H7菌株的RNA适体以特异性结合菌株并防止食物衰变。 构成:特异性结合大肠杆菌O157:H7的RNA适体具有选自序列号1-4的碱基。 序列号1-4的尿嘧啶(U)和胞嘧啶被2'羟基的氟取代。 用于检测大肠杆菌O157:H7的生物传感器含有RNA适体。 用于预防或治疗食物中毒,溶血性尿毒综合征或溶血性贫血的药物组合物含有该组合物。 食品添加剂组合物含有RNA适体。

    포도상구균의 테이코산에 대한 RNA 앱타머
    8.
    发明公开
    포도상구균의 테이코산에 대한 RNA 앱타머 有权
    。。。。。。。。。。。。。。。。。。。。

    公开(公告)号:KR1020130063013A

    公开(公告)日:2013-06-13

    申请号:KR1020137007652

    申请日:2011-12-14

    Abstract: PURPOSE: An RNA aptamer is provided to detect staphylococcus by specifically binding to teichoic acid of Staphylococcus aureus, to suppress activity of Staphylococcus aureus, and to prevent food spoilage. CONSTITUTION: An RNA aptamer has a base sequence of sequence number 1 which specifically binds to teichoic acid of Staphylococcus aureus. Urecil(U) and cytosine(C) of sequence number 1 have 2' hydroxyl group which is substituted with a fluorine group. A biosensor for detecting Staphylococcus aureus contains the RNA aptamer. A pharmaceutical composition for preventing or treating diseases selected from the group consisting of staphylococcal pneumonia, sepsis, osteomyelitis, staphylococcal enteritis, food poisoning, staphylococcal scalded skin syndrome(SSSS), and toxic shock-like syndrome(TSS) contains the RNA aptamer. A food additive composition contains the RNA aptamer.

    Abstract translation: 目的:提供RNA适配体,通过特异性结合金黄色葡萄球菌的磷壁酸来检测葡萄球菌,抑制金黄色葡萄球菌的活性,并防止食物变质。 构成:RNA适体具有序列号1的碱基序列,其特异性结合金黄色葡萄球菌的磷壁酸。 序列号1的Urecil(U)和胞嘧啶(C)具有被氟基取代的2'羟基。 用于检测金黄色葡萄球菌的生物传感器含有RNA适体。 用于预防或治疗选自葡萄球菌性肺炎,败血症,骨髓炎,葡萄球菌性肠炎,食物中毒,葡萄球菌性烫伤皮肤综合征(SSSS)和中毒性休克样综合征(TSS)的疾病的药物组合物含有RNA适体。 食品添加剂组合物含有RNA适体。

    살모넬라 티피뮤리움 균주의 ompC단백질에 대해 결합하는 RNA 앱타머
    9.
    发明公开
    살모넬라 티피뮤리움 균주의 ompC단백질에 대해 결합하는 RNA 앱타머 有权
    用于SALMONELLA TYPHIMIRIUM OMPC蛋白的RNA APTAMERS

    公开(公告)号:KR1020130063011A

    公开(公告)日:2013-06-13

    申请号:KR1020137007650

    申请日:2011-12-14

    Abstract: PURPOSE: An RNA aptamer is provided to detect Salmonella by specifically binding to ompC protein of Salmonella typhimirium which causes food poisoning, to suppress activity of Salmonella, and to prevent food decay. CONSTITUTION: An RNA aptamer has a base sequence of sequence number 1 or 2, which specifically binds to ompC protein of Salmonella typhimirium. Urecil(U) and cytosine(C) of sequence number 1 or 2 have 2' hydroxyl group which is substituted with a fluorine group. A biosensor for detecting Salmonella contains the RAN aptamer. A pharmaceutical composition for preventing or treating diseases selected from the group consisting of colitis, typhoid fever, and food poisoning contains the RNA aptamer. A food additive composition contains the RNA aptamer.

    Abstract translation: 目的:提供RNA适配体,通过特异性结合伤寒沙门氏菌的ompC蛋白来检测沙门氏菌,导致食物中毒,抑制沙门氏菌的活性,并防止食物衰变。 构成:RNA适体具有序列号1或2的碱基序列,其特异性结合盐酸沙门氏菌的ompC蛋白。 序列号1或2的Urecil(U)和胞嘧啶(C)具有被氟基团取代的2'羟基。 用于检测沙门氏菌的生物传感器含有RAN适体。 用于预防或治疗选自结肠炎,伤寒和食物中毒的疾病的药物组合物含有RNA适体。 食品添加剂组合物含有RNA适体。

    포도상구균의 테이코산에 대한 RNA 앱타머
    10.
    发明授权
    포도상구균의 테이코산에 대한 RNA 앱타머 有权
    。。。。。。。。。。。。。。。。。。。。

    公开(公告)号:KR101508219B1

    公开(公告)日:2015-04-07

    申请号:KR1020137007652

    申请日:2011-12-14

    Abstract: 본발명은포도상구균의테이코산에대한 RNA 앱타머에관한것으로서, 보다상세하게는포도상구균의테이코산에특이적으로결합하고, 그염기중 우라실(U) 및시토신(C)의 2' 히드록실기가플루오르기로치환되어있는서열번호 1의염기서열을가짐으로써식중독등의주요원인이되는포도상구균의검출에유용하고, 포도상구균에특이적으로결합하여그 작용을억제함으로써식품의부패를방지할수 있으며, 포도상구균성폐렴, 패혈증, 골수염, 포도상구균장염, 식중독, 포도상구균성열상유사증후군(SSSS) 및독소성충격증후군(TSS)으로이루어진군에서선택된질환의예방및 치료에유용한 RNA 앱타머에관한것이다.

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