Abstract:
본 발명은 Ramalina terebrata 로부터 분리한 항산화 활성이 뛰어난 신규 화합물에 관한 것으로, 더욱 자세하게는 남극지의류인 Ramalina terebrata 로부터 분리한 항산화 활성이 뛰어난 신규 화합물 라말린, 상기 라말린의 제조방법, 상기 라말린을 유효성분으로 함유하는 약학조성물, 기능성 식품 및 기능성 화장품에 관한 것이다.본 발명에 따른 라말린은 기존 시판되는 항산화제보다 월등히 뛰어난 항산화효과를 가지고 있어, 산화관련질환 치료제나, 노화방지용 기능성 식품, 미백 및 주름개선용 기능성 화장품 등에 널리 활용될 수 있다.
Abstract:
단백질 타이로신 탈인산화 효소 1B의 활성 억제능을 가지는 남극 지의류 스테레오카울론 알피넘(Stereocaulon alpinum) 추출물 및 이로부터 분리된 우스닉산 유도체가 개시된다. 본 발명에 따른 스테레오카울론 알피넘(Stereocaulon alpinum) 추출물 및 이로부터 분리된 우스닉산 유도체는 당뇨병의 주요 증상인 고혈당에 대한 혈당강하 효과를 갖는다.
스테레오카울론 알피넘(Stereocaulon alpinum), 단백질 타이로신 탈인산화효소 1B(PTP1B)
Abstract:
A Hahella chejuensis mutant strain is provided to stably produce prodigiosin with high yield. A Hahella chejuensis mutant strain M3349(KCTC 11276BP) has high productivity of prodigiosin. A method for isolating the Hahella chejuensis mutant strain M3349(KCTC 11276BP) comprises: a step of treating Hahella chejuensis KCTC 2396 with antibiotics or ethyl methane sulfonate (EMS) to induce mutation; a step of separating a colony in which prodigiosin pigmentation is formed; and a step of culturing the colony in the medium containing antibiotics or carbon source to select a colony having high productivity of prodigiosin.
acrtica ) KOPRI 21653 및 상기 균주 유래 엑소폴리사카라이드(exopolysaccharide)에 관한 것으로, 더욱 자세하게는 슈도알터로모나스 알티카( Pseudoaltermonas
acrtica ) KOPRI 21653 및 상기 균주 유래 항동결능을 가지는 신규 엑소폴리사카라이드, 그 제조 방법 및 이를 함유하는 항동결용 조성물에 관한 것이다. 본 발명에 따른 신규의 엑소폴리사카라이드 및 이를 함유하는 항동결 조성물은 조직의 손상을 최소화하면서 세포 및 조직을 포함하는 생물학적 시료를 냉장, 냉동 및 유리화 상태로 보호 또는 보존하는데 매우 유용하다. 세포외다당체, 엑소폴리사카라이드, 항동결
Abstract:
An algicidal agent containing prodigiosin and a prodigiosin biosynthetic gene cluster are provided to kill reddish brown tide-causing bacteria including Cochlodinium polykrikoides, Gyrodinium impudicum and Heterosigma akashiwo. The prodigiosin biosynthetic gene cluster comprises the nucleotide sequence of SEQ ID NO:1. A method for producing the prodigiosin comprises the steps of: producing a vector containing the prodigiosin biosynthetic gene cluster; transforming a cell with the vector; and culturing the transformed cell. The algicidal agent contains prodigiosin.
Abstract:
PURPOSE: A microorganism Alteromonas sp. 00SS11568 and a method for preparation of extracellular polysaccharide therefrom are provided, which polysaccharide is heteropolysaccharide consisting of glucose and galactose in a ratio of 3:1, and has improved emulsion stability, so that it can be used as biological materials for production of industrial materials. CONSTITUTION: The microorganism Alteromonas sp. 00SS11568(KCTC 10324BP) produces exopolysaccharide p-11568 which consists of glucose and galactose in a ratio of 3:1 and has molecular weight of 440 kDa, wherein Alteromonas sp. 00SS11568(KCTC 10324BP) is isolated from the biological membrane form on the sea contacting with rivers. The method for preparation of exopolysaccharide p-11568 comprises the steps of: inoculating Alteromonas sp. 00SS11568(KCTC 10324BP) in a medium containing inorganic nitrogen, organic nitrogen, inorganic phosphate, MgSO4, CaCl2 and glucose; and culturing it at 25 deg. C and pH 8.
Abstract:
PURPOSE: A preservation method of oil compound degrading microorganisms using chitin is provided which saves time and cost for preservation process of microorganism. CONSTITUTION: Oil compound degrading microorganism is cultured in the inorganic nutrient salt medium containing oil and diluted with the same medium. The diluted culture broth is applied to chitin powder then microorganism is absorbed into the chitin powder. The amount of culture broth is adjusted under 1.5 times of chitin. This process keeps the number of viable cells maximum in the inoculation step and maintains degradability of microorganism. The microorganism used for decontamination of oil compound includes bacteria and yeast and this method can be used to preserve those microorganism. Acinetobacter sp. US1 (KCTC 8618P), Yarrowia lipolytica CL180 (KCTC 0533BP), Sphingomonas sp. KH3-2 (KCTC 8815P), Acinetobacter sp. K2-2, Pseudomonas sp. K12-5 and Moraxella sp. K12-7 are preserved well using this method.
Abstract:
PURPOSE: Streptomyces sp. 8321 strains having emulsion property and method for separating oil from an emulsion liquid by destroying an emulsion using the strains are provided which can be achieved in high yield promptly and prevent environmental pollution. CONSTITUTION: Streptomyces sp. 8321 strains(KCTC 0518BP) having demulsion property and a method for separating oil from an oil-in-water emulsion liquid using the same are provided. The method comprises mixing a spore solution of the strains with waste water or the emulsion generated from polluted soil by oil and separating by destroying the emulsion. The Streptomyces sp. 8321 strains are quick in its effect on separating(diminish to half in volume within 1 min) and enable to achieve more than 95% recovery.
Abstract:
본 발명은 페난트렌 분해능을 갖는 신규한 스핑고모나스 ( Sphingomonas )속 미생물에 관한 것이다. 본 발명에 따른 스핑고모나스 속 균주 KH3-2는 500ppm의 페난트렌을 2주후 70% 이상, 1,000ppm의 페난트렌을 4주후 50%이상 분해하며, 10,000ppm의 페난트렌에서도 분해 특성을 나타낸다.