公开(公告)号：KR1020040098746A

公开(公告)日：2004-11-26

申请号：KR1020030030982

申请日：2003-05-15

Applicant: 한국화학연구원

Inventor： 이해방 ,  강길선 ,  정제교 ,  윤덕일 ,  조선행 ,  이진수 ,  유제영

IPC: A61K47/30

CPC classification number: A61K9/0024 ,  A61K9/1629

Abstract: PURPOSE: Provided is a controlled drug delivery system of a locally implantable agent which controls an initial release speed and duration of drug by adding a biodegradable polymer as a carrier and its monomers to reduce toxicity due to drug-overadministration and other adverse side effects. CONSTITUTION: The controlled drug delivery system of a locally implantable agent is characterized by including or dispersing an effective amount of drug in a mixture of 20-99 wt.% of a biodegradable polymer as a carrier and 1-80 wt.% of its monomers.

Abstract translation: 目的：提供一种局部植入药物的受控药物递送系统，其通过添加可生物降解的聚合物作为载体和其单体来控制药物的初始释放速度和持续时间，以减少由于药物过量给药引起的毒性和其他不良副作用。 构成：本地可植入药物的受控药物递送系统的特征在于将有效量的药物包含或分散在20-99重量％的可生物降解的聚合物作为载体和1-80重量％的单体的混合物中 。