公开(公告)号：WO2012112321A2

公开(公告)日：2012-08-23

申请号：PCT/US2012/023911

申请日：2012-02-06

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  ABUELYAMAN, Ahmed S. ,  ECKERT, Adrian S. ,  MITRA, Sumita B. ,  DUNBAR, Timothy D. ,  CRAIG, Bradley D. ,  CAO, Chuntao

Inventor： ABUELYAMAN, Ahmed S. ,  ECKERT, Adrian S. ,  MITRA, Sumita B. ,  DUNBAR, Timothy D. ,  CRAIG, Bradley D. ,  CAO, Chuntao

IPC: A61K6/083

CPC classification number: A61K6/083 ,  A61K6/0005 ,  A61K6/0008 ,  A61K6/0061 ,  A61K6/0073 ,  A61K6/09 ,  C08L33/08 ,  C08L33/10

Abstract: Hardenable compositions are described comprising at least one multifunctional ethylenically unsaturated isocyanurate monomer and at least one multifunctional ethylenically unsaturated tricyclodecane monomer. In favored embodiments, the compositions further comprise filler and are suitable dental restorations.

Abstract translation: 描述了包含至少一种多官能烯键式不饱和异氰脲酸酯单体和至少一种多官能烯键式不饱和三环癸烷单体的可硬化组合物。 在有利的实施方案中，组合物还包含填充剂并且是适合的牙齿修复体。

公开(公告)号：WO2015034977A1

公开(公告)日：2015-03-12

申请号：PCT/US2014/053977

申请日：2014-09-04

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： MILLER, Adam D. ,  FREY, Matthew H. ,  DUNBAR, Timothy D. ,  LOLL, Henry ,  THALACKER, Christoph

IPC: A61K6/00 ,  A61K6/083

CPC classification number: A61K6/087 ,  A61K6/0023 ,  A61K6/0073 ,  A61K6/083 ,  C08L33/00

Abstract: The invention relates to a curable composition for dental use comprising polyoxymetalates and/or derivatives thereof in an amount of at least about 5 wt.-% with respect to the weight of the composition.

Abstract translation: 本发明涉及用于牙科用途的可固化组合物，其包含相对于组合物重量为至少约5重量％的量的聚氧化金属盐和/或其衍生物。

公开(公告)号：WO2012112350A3

公开(公告)日：2012-08-23

申请号：PCT/US2012/024222

申请日：2012-02-08

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  JOLY, Guy D. ,  KREPSKI, Larry R. ,  GADDAM, Babu N. ,  ABUELYAMAN, Ahmed S. ,  CRAIG, Bradley D. ,  DUNBAR, Timothy D. ,  CAO, Chuntao ,  OXMAN, Joel D. ,  FALSAFI, Afshin ,  MOSER, William H. ,  BUI, Hoa T.

Inventor： JOLY, Guy D. ,  KREPSKI, Larry R. ,  GADDAM, Babu N. ,  ABUELYAMAN, Ahmed S. ,  CRAIG, Bradley D. ,  DUNBAR, Timothy D. ,  CAO, Chuntao ,  OXMAN, Joel D. ,  FALSAFI, Afshin ,  MOSER, William H. ,  BUI, Hoa T.

IPC: A61K6/083

Abstract: Dental compositions are described comprising an addition-fragmentation agent comprising at least one ethylenically unsaturated terminal group and a backbone unit comprising an α, β- unsaturated carbonyl; at least one monomer comprising at least two ethylenically unsaturated group; and inorganic oxide filler. The addition-fragmentation agent is preferably free-radically cleavable. The addition-fragmentation agent preferably comprises at least two ethylenically unsaturated terminal groups, such as (meth)acTylate groups. In some embodiments, the addition- fragmentation agent has the formula: wherein R 1 , R 2 and R 3 are each independently Ζ m ,-Q-, a (hetero)alkyl group or a (hetero)aryl group with the proviso that at least one of R 1 , R 2 and R 3 is Z m -Q-; Q is a linking group have a valence of m +1; Z is an ethylenically unsaturated polymerizable group; m is 1 to 6; each X1 is independently -O- or -NR 4 -, where R 4 is H or C 1 -C 4 alkyl; and n is 0 or 1. Also described are dental articles prepared from a dental composition comprising an addition- fragmentation agent and methods of treating a tooth surface.

公开(公告)号：WO2017136374A1

公开(公告)日：2017-08-10

申请号：PCT/US2017/015928

申请日：2017-02-01

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： CRAIG, Bradley D. ,  DUNBAR, Timothy D. ,  DEDE, Karsten ,  ECKERT, Adrain S. ,  ABUELYAMAN, Ahmed S. ,  KOBUSSEN, Gregory A. ,  THALACKER, Christoph H. ,  HOMNICK, Paul J.

IPC: A61K6/083 ,  A61K6/02 ,  A61K6/00

CPC classification number: A61K6/0005 ,  A61K6/0008 ,  A61K6/0073 ,  A61K6/0094 ,  A61K6/024 ,  A61K6/083 ,  C08L33/08 ,  C08L33/10

Abstract: Dental compositions and methods of formulating a dental composition are described. In one embodiment, the dental composition comprises a polymerizable resin comprising one or more ethylenically unsaturated monomers or oligomers and nanoparticles. The nanoparticles have a refractive index of at least 1.600 and an average discrete or aggregate particle size of no greater than 100 nm. The dental composition further comprises inorganic metal oxide filler having a discrete or aggregate average particle size of at least 200 nm. The nanoparticles are present at a concentration to provide a refractive index differential between the cured polymerizable resin and inorganic metal oxide filler such that the contrast ratio of the dental composition is at least 40.

Abstract translation: 描述了牙科组合物和配制牙科组合物的方法。 在一个实施方案中，牙科组合物包含含有一种或多种烯键式不饱和单体或低聚物和纳米颗粒的可聚合树脂。 纳米粒子具有至少1.600的折射率和不大于100nm的平均离散或聚集粒度。 牙科组合物还包含具有至少200nm的离散或聚集平均粒度的无机金属氧化物填料。 纳米颗粒以一定浓度存在，以提供固化的可聚合树脂和无机金属氧化物填料之间的折射率差异，使得牙科组合物的对比率至少为40。

公开(公告)号：WO2009085721A1

公开(公告)日：2009-07-09

申请号：PCT/US2008/086914

申请日：2008-12-16

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  DUNBAR, Timothy D.

Inventor： DUNBAR, Timothy D.

IPC: C09C1/04 ,  C01G9/02 ,  C09C3/08

CPC classification number: C09C1/043 ,  B82Y30/00 ,  C01F7/02 ,  C01G1/02 ,  C01G9/02 ,  C01G15/00 ,  C01G19/02 ,  C01G21/02 ,  C01G23/04 ,  C01G31/02 ,  C01G37/02 ,  C01G45/02 ,  C01P2004/64 ,  C09C3/08 ,  Y10S977/773 ,  Y10S977/811

Abstract: A composition comprises surface-modified nanoparticles of at least one amphoteric metal oxide or oxyhydroxide. The nanoparticles bear, on at least a portion of their surfaces, a surface modification comprising (i) at least one surface modifier selected from lactate, thiolactate, and mixtures thereof, and (ii) at least one surface modifier selected from halide, nitrate, acetate, carbonate, formate, propionate, sulfate, bromate, perchlorate, tribromoacetate, trichloroacetate, trifluoroacetate, carboxylate comprising from one to about four alkyleneoxy moieties, chlorate, and mixtures thereof.

Abstract translation: 组合物包含至少一种两性金属氧化物或羟基氧化物的表面改性的纳米颗粒。 所述纳米颗粒在其表面的至少一部分上具有表面改性，其包含（i）至少一种选自乳酸盐，硫代乳酸盐及其混合物的表面改性剂，和（ii）至少一种选自卤化物，硝酸盐， 乙酸盐，碳酸盐，甲酸盐，丙酸盐，硫酸盐，溴酸盐，高氯酸盐，三溴乙酸盐，三氯乙酸盐，三氟乙酸盐，含1至约4个亚烷氧基部分的羧酸盐及其混合物。

公开(公告)号：WO2020049503A1

公开(公告)日：2020-03-12

申请号：PCT/IB2019/057499

申请日：2019-09-05

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： LIN, Ying ,  YE, Sheng ,  DUNBAR, Timothy D. ,  CRAIG, Bradley D. ,  ZHU, Dong-Wei ,  KRYGER, Matthew J. ,  POKORNY, Richard J. ,  KROPP, Michael A.

IPC: C09D4/00

Abstract: A curable composition that includes a urethane multifunctional (meth)acrylate, an inorganic filler having a primary particle dimension of at least 200 nm, a photoinitiator system that can be activated by electromagnetic radiation in the range of 340 – 550 nm, a reactive diluent, and a reinforcing silica having a primary particle dimension of 100 nm of less. The sum of the absolute value of the difference in the refractive index of the filler and the refractive index of the composition cured without filler plus the birefringence of the filler is 0.054 or less, i.e. 0.054 ≥ |n filler – n matrix | + δ filler , where n filler is the refractive index of the filler, n matrix is the refractive index of the composition cured without filler, and δ filler is the birefringence of the filler.

公开(公告)号：WO2019048963A1

公开(公告)日：2019-03-14

申请号：PCT/IB2018/056371

申请日：2018-08-22

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： PARKAR, Zeba ,  HANSEN, James D. ,  WU, Tianyu ,  FRANKE, Carsten ,  DUNBAR, Timothy D. ,  KOBUSSEN, Gregory A. ,  ABUELYAMAN, Ahmed S. ,  CRAIG, Bradley D.

IPC: A61C13/087 ,  A61K6/083 ,  A61K6/06 ,  A61C19/00 ,  C08K3/013 ,  C08F22/10 ,  C08F222/10 ,  B33Y10/00 ,  B33Y70/00 ,  B33Y80/00 ,  B29C64/124

Abstract: A radiation curable composition including at least one radiation hardenable component, a photo-initiator, and a filler material having a population of particulates in an amount greater than or equal to 50% by weight of the printable composition. The population of particulates exhibits a median diameter (D50) of greater than or equal to 0.3 micrometer on a volume-average basis as determined using the Particle Size Test Method, and the radiation curable composition exhibits a viscosity of less than or equal to 150 Pa s when measured using the Viscosity Test Method. A method, apparatus, and systems for producing composite articles by selectively exposing a portion of the radiation curable composition to a source of actinic radiation to at least partially cure the exposed portion of the radiation curable composition, thereby forming a hardened layer, preferably by an additive manufacturing process such as stereophotolithography, are also described. The composite articles may include composite dental restorations.

公开(公告)号：WO2008079800A1

公开(公告)日：2008-07-03

申请号：PCT/US2007/087857

申请日：2007-12-18

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  DUNBAR, Timothy D.

Inventor： DUNBAR, Timothy D.

IPC: C09C1/04 ,  B82B3/00

CPC classification number: C01G9/02 ,  B82Y30/00 ,  C01P2002/84 ,  C01P2004/64 ,  C09C1/043 ,  Y10S977/773 ,  Y10S977/774 ,  Y10S977/775

Abstract: A process comprises (a) combining (1) at least one base and (2) at least one metal carboxylate salt comprising (i) a metal cation selected from metal cations that form amphoteric metal oxides or oxyhydroxides and (ii) a carboxylate anion comprising from one to four alkyleneoxy moieties, or metal carboxylate salt precursors comprising (i) at least one metal salt comprising the metal cation and a non-interfering anion and (ii) at least one carboxylic acid comprising from one to four alkyleneoxy moieties, at least one salt of the carboxylic acid and a non-interfering, non-metal cation, or a mixture thereof; and (b) allowing the base and the metal carboxylate salt or metal carboxylate salt precursors to react.

Abstract translation: 一种方法包括（1）组合（1）至少一种碱和（2）至少一种金属羧酸盐，其包含（i）选自形成两性金属氧化物或羟基氧化物的金属阳离子的金属阳离子和（ii）包含 其包含（i）至少一种包含金属阳离子和非干扰阴离子的金属盐，和（ii）至少一种包含一至四个亚烷氧基部分的羧酸，至少包含一个至四个亚烷基氧基部分 羧酸的一种盐和非干扰性非金属阳离子或其混合物; 和（b）使碱和金属羧酸盐或金属羧酸盐前体反应。

公开(公告)号：EP2675421A2

公开(公告)日：2013-12-25

申请号：EP12703675.4

申请日：2012-02-06

Applicant: 3M Innovative Properties Company

Inventor： ABUELYAMAN, Ahmed S. ,  ECKERT, Adrian S. ,  MITRA, Sumita B. ,  DUNBAR, Timothy D. ,  CRAIG, Bradley D. ,  CAO, Chuntao

IPC: A61K6/083 ,  A61K6/09 ,  A61K6/00

CPC classification number: A61K6/083 ,  A61K6/0005 ,  A61K6/0008 ,  A61K6/0061 ,  A61K6/0073 ,  A61K6/09 ,  C08L33/08 ,  C08L33/10

Abstract: Hardenable compositions are described comprising at least one multifunctional ethylenically unsaturated isocyanurate monomer and at least one multifunctional ethylenically unsaturated tricyclodecane monomer. In favored embodiments, the compositions further comprise filler and are suitable dental restorations.

公开(公告)号：EP2675422A2

公开(公告)日：2013-12-25

申请号：EP12704603.5

申请日：2012-02-08

Applicant: 3M Innovative Properties Company

Inventor： JOLY, Guy D. ,  KREPSKI, Larry R. ,  GADDAM, Babu N. ,  ABUELYAMAN, Ahmed S. ,  CRAIG, Bradley D. ,  DUNBAR, Timothy D. ,  CAO, Chuntao ,  OXMAN, Joel D. ,  FALSAFI, Afshin ,  MOSER, William H. ,  BUI, Hoa T.

IPC: A61K6/083

Abstract: Dental compositions comprising an addition-fragmentation agent having the formula: wherein R 1 , R 2 and R 3 are each independently Z m -Q-, a (hetero)alkyl group or a (hetero)aryl group with the proviso that at least two of R 1 , R 2 and R 3 is Z m -Q-; Q is a linking group have a valence of m +1; Z is an ethylenically unsaturated polymerizable group; m is 1 to 6; each X 1 is independently -O- or -NR 4 -, where R 4 is H or C 1 -C 4 alkyl; and n is 0 or 1; at least one multifunctional monomer comprising at least two ethylenically unsaturated group; optionally an inorganic filler; and a redox initiator system; and the use thereof are described.