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    DETERMINATION OF GLYCATED HEMOGLOBIN BY FLUORESCENCE QUENCHING
    2.
    发明公开
    DETERMINATION OF GLYCATED HEMOGLOBIN BY FLUORESCENCE QUENCHING 失效
    通过荧光检测测定糖化血红蛋白

    公开(公告)号：EP0589001A4

    公开(公告)日：1996-01-31

    申请号：EP93906278

    申请日：1993-03-03

    Applicant: ABBOTT LAB

    Inventor： BRANDT DOUGLAS R ,  BROWN WILLIAM E ,  LANE THERESA L ,  WILSON DAVID H

    IPC: G01N21/78 ,  G01N33/53 ,  G01N33/72 ,  G01N30/48

    CPC classification number: G01N33/723 ,  Y10S435/968

    Abstract: The present invention relates to the measurement of glycated hemoglobin by fluorescence quenching. The present invention uniquely involves performing two sequential fluorescent quenching measurements: one measurement of the fluorescent quenching due to total hemoglobin in the sample and a second measurement of the fluorescent quenching due to glycated hemoglobin present in the sample after the non-glycated hemoglobin is removed. Glycated hemoglobin and non-glycated hemoglobin can be separated by a variety of methods as described herein, including ion capture and solid phase separations.

    4.
    发明专利
    未知

    公开(公告)号：DE68920176D1

    公开(公告)日：1995-02-09

    申请号：DE68920176

    申请日：1989-03-22

    Applicant: ABBOTT LAB

    Inventor： BROWN WILLIAM E ,  SAFFORD SARAH E ,  CLEMENS JOHN M

    IPC: G01N33/52 ,  G01N33/543 ,  G01N33/569 ,  G01N33/576 ,  G01N33/76 ,  G01N33/558

    Abstract: A novel material and device useful in solid-phase binding assays to determine the presence or amount of an analyte in a test sample, particularly antigens, antibodies, or other ligands or DNA segments. The material and device comprises a reaction site having procedural controls and an analyte binding area capable of being simultaneously contacted by the sample and reagent used in the performance of the assay. The procedural controls and analyte binding areas operate to provide readable results as to the presence or absence of analyte and simultaneously verify the assay procedure and therefore the assay result.

    6.
    发明专利
    未知

    公开(公告)号：DE68920176T2

    公开(公告)日：1995-05-11

    申请号：DE68920176

    申请日：1989-03-22

    Applicant: ABBOTT LAB

    Inventor： BROWN WILLIAM E ,  SAFFORD SARAH E ,  CLEMENS JOHN M

    IPC: G01N33/52 ,  G01N33/543 ,  G01N33/569 ,  G01N33/576 ,  G01N33/76 ,  G01N33/558

    Abstract: A novel material and device useful in solid-phase binding assays to determine the presence or amount of an analyte in a test sample, particularly antigens, antibodies, or other ligands or DNA segments. The material and device comprises a reaction site having procedural controls and an analyte binding area capable of being simultaneously contacted by the sample and reagent used in the performance of the assay. The procedural controls and analyte binding areas operate to provide readable results as to the presence or absence of analyte and simultaneously verify the assay procedure and therefore the assay result.

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