公开(公告)号：BR9813468A

公开(公告)日：2001-11-13

申请号：BR9813468

申请日：1998-12-11

Applicant: ABBOTT LAB

Inventor： HENKIN JACK ,  DAVISON DONALD J ,  SHEPPARD GEORGE S ,  WOODS KEITH W ,  MCCROSKEY RICHARD W

IPC: A61K31/53 ,  A61P27/02 ,  A61P35/00 ,  A61P43/00 ,  C07D251/18 ,  C07D401/04 ,  C07D401/10 ,  C07D401/12 ,  C07D403/04 ,  C07D405/04 ,  C07D405/10 ,  C07D407/04 ,  C07D407/10 ,  C07D409/04 ,  C07D409/06 ,  C07D409/10 ,  C07D413/10 ,  C07D417/04 ,  C07D453/02

Abstract: Compounds having Formula (I) or pharmaceutically acceptable salts or prodrugs thereof, are useful for treating pathological states which arise from or are exacerbated by angiogenesis. The invention also relates to pharmaceutical compositions comprising these compounds and to methods of inhibiting angiogenesis in a mammal.