公开(公告)号：SE8008533L

公开(公告)日：1980-12-04

申请号：SE8008533

申请日：1980-12-04

Applicant: ABBOTT LAB

Inventor： WINN M ,  KYNCL J ,  DUNNINGAN D A ,  JONES P H

IPC: C07D405/12 ,  A61K31/505 ,  A61P9/12 ,  A61P25/04 ,  C07D309/08 ,  C07D405/14

Abstract: Described are antihypertensive agents selected from the class consisting of 2[4(tetrahydro-2-furoyl)-piperazino]-4-amino-6,7-dimethoxyquinazoline and 2-[4(tetrahydropyran-2-carbonyl)-piperazinyl]-4-amino-6,7-dimethoxyqui nazoline, and pharmaceutically acceptable acid addition salts thereof. The compounds are highly water soluble and can be administered in time release form as well as parenterally, including intravenously.