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公开(公告)号：WO9950275A3
公开(公告)日：2001-02-22
申请号：PCT/US9904658
申请日：1999-03-11
Applicant: ABBOTT LAB
Inventor： SAUER DARYL R , HAVIV FORTUNA , RANDOLPH JOHN , MORT NICHOLAS A , DALTON CHRISTOPHER R , BRUNCKO MILAN , KAMINSKI MICHELE A , CRAWFORD BRADLEY W , FREY LISA MARIE , GREER JONATHON
IPC: A61K31/7042 , A61K31/7048 , A61K31/7056 , A61P5/24 , A61P13/08 , A61P15/00 , A61P35/00 , A61P43/00 , C07H17/08 , A61K31/70
CPC classification number: C07H17/08
Abstract: Disclosed are 3'-N-desmethyl-3'-N-susbstituted-6-O-methyl-11-deoxy-11, 12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
Abstract translation: 公开了作为促黄体激素释放激素（LHRH）的拮抗剂的3'-N-去甲基-3'-N-疑似取代的-6-O-甲基-11-脱氧-11,12-环状氨基甲酸酯红霉素A衍生物。 还公开了包含该化合物的药物组合物，使用该化合物的方法及其制备方法。
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公开(公告)号：BG104844A
公开(公告)日：2001-07-31
申请号：BG10484400
申请日：2000-10-11
Applicant: ABBOTT LAB
Inventor： SAUER DARYL R , HAVIV FORTUNA , RANDOLPH JOHN , MORT NICHOLAS A , DALTON CHRISTOPHER R , BRUNCKO MILAN , KAMINSKI MICHELE A , CRAWFORD BRADLEY W , FREY LISA M , GREER JONATHON
IPC: A61K31/7042 , A61K31/7048 , A61K31/7056 , A61P5/24 , A61P13/08 , A61P15/00 , A61P35/00 , A61P43/00 , C07H17/08 , C07H1/00
Abstract: Disclosed are 3'-N-desmethyl-3'-N-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same. 15 claims
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公开(公告)号：DE69923835D1
公开(公告)日：2005-03-31
申请号：DE69923835
申请日：1999-03-11
Applicant: ABBOTT LAB
Inventor： SAUER R , HAVIV FORTUNA , RANDOLPH JOHN , MORT A , DALTON R , BRUNCKO MILAN , KAMINSKI A , CRAWFORD W , FREY MARIE , GREER JONATHON
IPC: A61K31/7042 , A61K31/7048 , A61K31/7056 , A61P5/24 , A61P13/08 , A61P15/00 , A61P35/00 , A61P43/00 , C07H17/08 , C08F10/00
Abstract: Disclosed are 3'-N-desmethyl-3'-N-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
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公开(公告)号：AT289609T
公开(公告)日：2005-03-15
申请号：AT99912259
申请日：1999-03-11
Applicant: ABBOTT LAB
Inventor： SAUER DARYL R , HAVIV FORTUNA , RANDOLPH JOHN , MORT NICHOLAS A , DALTON CHRISTOPHER R , BRUNCKO MILAN , KAMINSKI MICHELE A , CRAWFORD BRADLEY W , FREY LISA MARIE , GREER JONATHON
IPC: A61K31/7042 , A61K31/7048 , A61K31/7056 , A61P5/24 , A61P13/08 , A61P15/00 , A61P35/00 , A61P43/00 , C07H17/08 , A61K31/70
Abstract: Disclosed are 3'-N-desmethyl-3'-N-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
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公开(公告)号：CA2325519A1
公开(公告)日：1999-10-07
申请号：CA2325519
申请日：1999-03-22
Applicant: ABBOTT LAB
Inventor： CRAWFORD BRADLEY W , KAMINSKI MICHELE A , FREY LISA MARIE , BRUNCKO MILAN , SAUER DARYL R , GREER JONATHON , HAVIV FORTUNA , RANDOLPH JOHN , MORT NICHOLAS A , DALTON CHRISTOPHER R
IPC: A61K31/7042 , A61K31/7048 , A61P5/00 , A61P15/00 , A61P43/00 , C07H17/08 , A61K31/70
Abstract: Disclosed are 3',3'-N-bisdesmethyl-3',3'-N-bis-substituted-6-O-methyl-11-deoxy-11,12 -cyclic carbamate erythromycin A derivatives of formula (I) which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, methods of using the compounds and the process of making the same.
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Patent Agency Ranking
公开(公告)号：SI1066304T1
公开(公告)日：2005-10-31
申请号：SI9930779
申请日：1999-03-11
Applicant: ABBOTT LAB
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公开(公告)号：HU0102522A2
公开(公告)日：2001-10-28
申请号：HU0102522
申请日：1999-03-22
Applicant: ABBOTT LAB
Inventor： BRUNCKO MILAN , CRAWFORD BRADLEY W , DALTON CHRISTOPHER R , FREY LISA MARIE , GREER JONATHON , HAVIV FORTUNA , KAMINSKI MICHELE A , MORT NICHOLAS A , RANDOLPH JOHN , SAUER DARYL R
IPC: A61K31/7042 , A61K31/7048 , A61P5/00 , A61P15/00 , A61P43/00 , C07H17/08
Abstract: Disclosed are 3',3'-N-bisdesmethyl-3',3'-N-bis-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
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公开(公告)号：TR200002766T2
公开(公告)日：2001-01-22
申请号：TR200002766
申请日：1999-03-22
Applicant: ABBOTT LAB
Inventor： SAUER DARYL R , HAVIV FORTUNA , RANDOLPH JOHN , MORT NICHOLAS A , DALTON CHRISTOPHER R , BRUNCKO MILAN , KAMINSKI MICHELE A , CRAWFORD BRADLEY W , FREY LISA MARIE , GREER JONATHON
IPC: A61K31/7042 , A61K31/7048 , A61P5/00 , A61P15/00 , A61P43/00 , C07H17/08 , A61K31/70
Abstract: Disclosed are 3',3'-N-bisdesmethyl-3',3'-N-bis-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
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公开(公告)号：AU3197599A
公开(公告)日：1999-10-18
申请号：AU3197599
申请日：1999-03-22
Applicant: ABBOTT LAB
Inventor： SAUER DARYL R , HAVIV FORTUNA , RANDOLPH JOHN , MORT NICHOLAS A , DALTON CHRISTOPHER R , BRUNCKO MILAN , KAMINSKI MICHELE A , CRAWFORD BRADLEY W , FREY LISA MARIE , GREER JONATHON
IPC: A61K31/7042 , A61K31/7048 , A61P5/00 , A61P15/00 , A61P43/00 , C07H17/08 , A61K31/70
Abstract: Disclosed are 3',3'-N-bisdesmethyl-3',3'-N-bis-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
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公开(公告)号：DK1066304T3
公开(公告)日：2005-06-20
申请号：DK99912259
申请日：1999-03-11
Applicant: ABBOTT LAB
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