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公开(公告)号：WO9950275A3
公开(公告)日：2001-02-22
申请号：PCT/US9904658
申请日：1999-03-11
Applicant: ABBOTT LAB
Inventor： SAUER DARYL R , HAVIV FORTUNA , RANDOLPH JOHN , MORT NICHOLAS A , DALTON CHRISTOPHER R , BRUNCKO MILAN , KAMINSKI MICHELE A , CRAWFORD BRADLEY W , FREY LISA MARIE , GREER JONATHON
IPC: A61K31/7042 , A61K31/7048 , A61K31/7056 , A61P5/24 , A61P13/08 , A61P15/00 , A61P35/00 , A61P43/00 , C07H17/08 , A61K31/70
CPC classification number: C07H17/08
Abstract: Disclosed are 3'-N-desmethyl-3'-N-susbstituted-6-O-methyl-11-deoxy-11, 12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
Abstract translation: 公开了作为促黄体激素释放激素（LHRH）的拮抗剂的3'-N-去甲基-3'-N-疑似取代的-6-O-甲基-11-脱氧-11,12-环状氨基甲酸酯红霉素A衍生物。 还公开了包含该化合物的药物组合物，使用该化合物的方法及其制备方法。
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公开(公告)号：BG104844A
公开(公告)日：2001-07-31
申请号：BG10484400
申请日：2000-10-11
Applicant: ABBOTT LAB
Inventor： SAUER DARYL R , HAVIV FORTUNA , RANDOLPH JOHN , MORT NICHOLAS A , DALTON CHRISTOPHER R , BRUNCKO MILAN , KAMINSKI MICHELE A , CRAWFORD BRADLEY W , FREY LISA M , GREER JONATHON
IPC: A61K31/7042 , A61K31/7048 , A61K31/7056 , A61P5/24 , A61P13/08 , A61P15/00 , A61P35/00 , A61P43/00 , C07H17/08 , C07H1/00
Abstract: Disclosed are 3'-N-desmethyl-3'-N-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same. 15 claims
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公开(公告)号：SK13972000A3
公开(公告)日：2001-07-10
申请号：SK13972000
申请日：1999-03-11
Applicant: ABBOTT LAB
Inventor： SAUER DARYL R , HAVIV FORTUNA , RANDOLPH JOHN , MORT NICHOLAS A , DALTON CHRISTOPHER R , BRUNCKO MILAN , KAMINSKI MICHELE A , CRAWFORD BRADLEY W , FREY LISA MARIE , GREER JONATHAN
IPC: A61K31/7042 , A61K31/7048 , A61K31/7056 , A61P5/24 , A61P13/08 , A61P15/00 , A61P35/00 , A61P43/00 , C07H17/08 , A61K31/70 , C07H1/00
Abstract: Disclosed are 3'-N-desmethyl-3'-N-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
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公开(公告)号：NO20004807A
公开(公告)日：2000-11-24
申请号：NO20004807
申请日：2000-09-26
Applicant: ABBOTT LAB
Inventor： SAUER DARYL R , HAVIV FORTUNA , RANDOLPH JOHN , MORT NICHOLAS A , DALTON CHRISTOPHER ROBIN , BRUNCKO MILAN , KAMINSKI MICHELE A , CRAWFORD BRADLEY W , FREY LISA MARIE , GREER JONATHAN
IPC: A61K31/7042 , A61K31/7048 , A61P5/00 , A61P15/00 , A61P43/00 , C07H17/08 , A61K31/70
CPC classification number: C07H17/08
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公开(公告)号：DK1066304T3
公开(公告)日：2005-06-20
申请号：DK99912259
申请日：1999-03-11
Applicant: ABBOTT LAB
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Patent Agency Ranking
公开(公告)号：BR9909080A
公开(公告)日：2000-12-12
申请号：BR9909080
申请日：1999-03-11
Applicant: ABBOTT LAB
Inventor： SAUER DARYL R , HAVIV FORTUNA , RANDOLPH JOHN , MORT NICHOLAS A , DALTON CHRISTOPHER R , BRUNCKO MILAN , KAMINSKI MICHELE A , CRAWFORD BRADLEY W , FREY LISA MARIE , GREER JONATHON
IPC: A61K31/7042 , A61K31/7048 , A61K31/7056 , A61P5/24 , A61P13/08 , A61P15/00 , A61P35/00 , A61P43/00 , C07H17/08 , A61K31/70 , C07H1/00
Abstract: Disclosed are 3'-N-desmethyl-3'-N-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
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公开(公告)号：NO20004860A
公开(公告)日：2000-11-24
申请号：NO20004860
申请日：2000-09-27
Applicant: ABBOTT LAB
Inventor： SAUER DARYL R , HAVIV FORTUNA , RANDOLPH JOHN , MORT NICHOLAS A , DALTON CHRISTOPHER ROBIN , BRUNCKO MILAN , KAMINSKI MICHELE A , CRAWFORD BRADLEY W , FREY LISA MARIE , GREER JONATHAN
IPC: A61K31/7042 , A61K31/7048 , A61K31/7056 , A61P5/24 , A61P13/08 , A61P15/00 , A61P35/00 , A61P43/00 , C07H17/08
CPC classification number: C07H17/08
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公开(公告)号：CA2351187A1
公开(公告)日：2000-05-25
申请号：CA2351187
申请日：1999-11-09
Applicant: ABBOTT LAB
Inventor： CRAWFORD BRADLEY W , HAVIV FORTUNA , SWENSON ROLF E , BRUNCKO MILAN , KAMINSKI MICHELE A , DWIGHT WESLEY J , FREY LISA M , DEMATTEI JOHN , GREER JONATHAN
IPC: C07D217/06 , A61K31/472 , A61K31/4725 , A61K31/4741 , A61K31/55 , A61P5/00 , A61P13/08 , A61P15/00 , A61P35/00 , C07D217/04 , C07D217/14 , C07D217/16 , C07D217/18 , C07D217/20 , C07D217/22 , C07D217/26 , C07D223/16 , C07D401/04 , C07D401/06 , C07D401/08 , C07D401/12 , C07D491/04 , C07D491/056 , C07D221/00 , C07D317/00 , C07D319/00 , C07D401/10
Abstract: Tetrahydroisoquinoline derivatives of formula (I): or a pharmaceutically acceptable salt, ester, or prodrug thereof, having activity as an LHRH antagonist, as well as pharmaceutical compositions containing the same, and methods for their use and preparation.
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公开(公告)号：AU3067499A
公开(公告)日：1999-10-18
申请号：AU3067499
申请日：1999-03-11
Applicant: ABBOTT LAB
Inventor： SAUER DARYL R , HAVIV FORTUNA , RANDOLPH JOHN , MORT NICHOLAS A , DALTON CHRISTOPHER R , BRUNCKO MILAN , KAMINSKI MICHELE A , CRAWFORD BRADLEY W , FREY LISA MARIE , GREER JONATHON
IPC: A61K31/7042 , A61K31/7048 , A61K31/7056 , A61P5/24 , A61P13/08 , A61P15/00 , A61P35/00 , A61P43/00 , C07H17/08
Abstract: Disclosed are 3'-N-desmethyl-3'-N-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
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公开(公告)号：SI1066304T1
公开(公告)日：2005-10-31
申请号：SI9930779
申请日：1999-03-11
Applicant: ABBOTT LAB
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