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公开(公告)号：WO2009149189A3
公开(公告)日：2010-03-04
申请号：PCT/US2009046137
申请日：2009-06-03
Applicant: ABBOTT LAB , GHAYUR TARIQ , ISAKSON PETER C , OLSON LISA M , WU CHENGBIN , HUGUNIN MARGARET , KAMATH RAJESH V , CUFF CAROLYN A , ALLEN HAMISH J
Inventor： GHAYUR TARIQ , ISAKSON PETER C , OLSON LISA M , WU CHENGBIN , HUGUNIN MARGARET , KAMATH RAJESH V , CUFF CAROLYN A , ALLEN HAMISH J
CPC classification number: C07K16/2887 , A61K39/3955 , A61K45/06 , A61K47/48546 , A61K47/6845 , A61K2039/505 , A61K2039/70 , C07K16/22 , C07K16/241 , C07K16/244 , C07K16/245 , C07K16/247 , C07K16/248 , C07K16/2866 , C07K16/468 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/64 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , G01N33/6869 , G01N2333/545
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白，制备方法，具体涉及用于预防，诊断和/或治疗疾病的用途。
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公开(公告)号：WO2011047262A3
公开(公告)日：2011-09-09
申请号：PCT/US2010052843
申请日：2010-10-15
Applicant: ABBOTT LAB , GHAYUR TARIQ , KAMATH RAJESH V , LIU JUNJIAN , HONORE MARIE P
Inventor： GHAYUR TARIQ , KAMATH RAJESH V , LIU JUNJIAN , HONORE MARIE P
CPC classification number: C07K16/00 , C07K16/22 , C07K16/241 , C07K16/245 , C07K16/2866 , C07K16/44 , C07K16/46 , C07K2317/21 , C07K2317/31 , C07K2317/56 , C07K2317/73 , C07K2317/76
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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公开(公告)号：WO2011047262A4
公开(公告)日：2011-11-10
申请号：PCT/US2010052843
申请日：2010-10-15
Applicant: ABBOTT LAB , GHAYUR TARIQ , KAMATH RAJESH V , LIU JUNJIAN , HONORE MARIE P
Inventor： GHAYUR TARIQ , KAMATH RAJESH V , LIU JUNJIAN , HONORE MARIE P
CPC classification number: C07K16/00 , C07K16/22 , C07K16/241 , C07K16/245 , C07K16/2866 , C07K16/44 , C07K16/46 , C07K2317/21 , C07K2317/31 , C07K2317/56 , C07K2317/73 , C07K2317/76
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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公开(公告)号：WO2012109373A3
公开(公告)日：2012-11-01
申请号：PCT/US2012024356
申请日：2012-02-08
Applicant: ABBOTT LAB , KAMATH RAJESH V
Inventor： KAMATH RAJESH V
IPC: A61K39/395 , C07K16/00
CPC classification number: C07K16/245 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/244 , C07K2317/24 , C07K2317/31 , C07K2317/51 , C07K2317/515 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The present invention relates to the treatment of osteoarthritis and pain using IL-1a and IL-1ß binding proteins, including anti-IL-1a and IL-1ß antibodies and engineered multivalent and multispecific IL-1a and IL-1ß binding proteins.
Abstract translation: 本发明涉及使用IL-1a和IL-1β结合蛋白（包括抗IL-1a和IL-1β抗体）和工程化多价和多特异性IL-1a和IL-1β结合蛋白来治疗骨关节炎和疼痛。
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公开(公告)号：EP2297209A4
公开(公告)日：2012-08-01
申请号：EP09759348
申请日：2009-06-03
Applicant: ABBOTT LAB
Inventor： GHAYUR TARIQ , ISAKSON PETER C , OLSON LISA M , WU CHENGBIN , HUGUNIN MARGARET , KAMATH RAJESH V , CUFF CAROLYN A , ALLEN HAMISH J
CPC classification number: C07K16/2887 , A61K39/3955 , A61K45/06 , A61K47/48546 , A61K47/6845 , A61K2039/505 , A61K2039/70 , C07K16/22 , C07K16/241 , C07K16/244 , C07K16/245 , C07K16/247 , C07K16/248 , C07K16/2866 , C07K16/468 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/64 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , G01N33/6869 , G01N2333/545
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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Patent Agency Ranking
公开(公告)号：DOP2012000104A
公开(公告)日：2013-01-31
申请号：DO2012000104
申请日：2012-04-13
Applicant: ABBOTT LAB
Inventor： HONORE MARIE P , GHAYUR TARIQ , LIU JUNJIAN , KAMATH RAJESH V
Abstract: Proteínas de unión multivalentes y multiespecificas modificadas, métodos para su obtención y específicamente sus usos en la prevención, diagnóstico yio tratamiento de enfermedades.
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公开(公告)号：AU2010306677A1
公开(公告)日：2012-05-31
申请号：AU2010306677
申请日：2010-10-15
Applicant: ABBOTT LAB
Inventor： GHAYUR TARIQ , KAMATH RAJESH V , LIU JUNJIAN , HONORE MARIE P
IPC: C07K16/24 , A61K39/395 , A61K51/10 , A61P1/04 , A61P3/10 , A61P5/00 , A61P7/06 , A61P9/00 , A61P9/10 , A61P11/00 , A61P13/12 , A61P15/00 , A61P17/06 , A61P19/02 , A61P19/08 , A61P25/16 , A61P31/00 , A61P31/12 , A61P31/18 , A61P35/00 , A61P35/02 , A61P37/00 , C07K16/46 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/13 , C12N15/63 , C12N15/70 , C12N15/80 , C12N15/81 , C12N15/82 , C12N15/85 , C12P21/08 , C12Q1/70
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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公开(公告)号：AU2009256250A1
公开(公告)日：2009-12-10
申请号：AU2009256250
申请日：2009-06-03
Applicant: ABBOTT LAB
Inventor： ISAKSON PETER C , KAMATH RAJESH V , ALLEN HAMISH J , GHAYUR TARIQ , OLSON LISA M , HUGUNIN MARGARET , WU CHENGBIN , CUFF CAROLYN A
IPC: C07K16/00 , A61K39/395 , C07H21/04 , C07K16/20 , C07K16/46 , C12N1/10 , C12N1/21 , C12N5/10 , C12N15/63 , C12P21/08
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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公开(公告)号：ECSP12011885A
公开(公告)日：2012-07-31
申请号：ECSP12011885
申请日：2012-05-11
Applicant: ABBOTT LAB
Inventor： GHAYUR TARIQ , KAMATH RAJESH V
IPC: A61K39/395 , A61K51/10 , A61P1/04 , A61P3/10 , A61P5/00 , A61P7/06 , A61P9/00 , A61P9/10 , A61P11/00 , A61P13/12 , A61P15/00 , A61P17/06 , A61P19/02 , A61P19/08 , A61P25/16 , A61P31/00 , A61P31/12 , A61P31/18 , A61P35/00 , A61P35/02 , A61P37/00 , C07K16/24 , C07K16/46 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/13 , C12N15/63 , C12N15/70 , C12N15/80 , C12N15/81 , C12N15/82 , C12N15/85 , C12P21/08
Abstract: Proteínas de unión multivalentes y multiespecíficas modificadas, métodos para su obtención y específicamente sus usos en la prevención, diagnóstico y/o tratamiento de enfermedades.
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公开(公告)号：CA2775959A1
公开(公告)日：2011-04-21
申请号：CA2775959
申请日：2010-10-15
Applicant: ABBOTT LAB
Inventor： GHAYUR TARIQ , KAMATH RAJESH V , LIU JUNJIAN , HONORE MARIE P
IPC: C07K16/46 , A61K39/395 , A61K51/10 , A61P1/04 , A61P3/10 , A61P5/00 , A61P7/06 , A61P9/00 , A61P9/10 , A61P11/00 , A61P13/12 , A61P15/00 , A61P17/06 , A61P19/02 , A61P19/08 , A61P25/16 , A61P31/00 , A61P31/12 , A61P31/18 , A61P35/00 , A61P35/02 , A61P37/00 , C07K16/22 , C07K16/24 , C12N15/13 , C12P21/08
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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