公开(公告)号：ZA7406331B

公开(公告)日：1975-12-31

申请号：ZA7406331

申请日：1974-10-04

Applicant: ABBOTT LAB

Inventor： OURS C ,  SOMANI P ,  JONES P ,  KUNCL J

IPC: A61K31/195 ,  A01N37/44 ,  A61K31/198 ,  A61K31/22 ,  A61P9/08 ,  C07C237/08 ,  A61K ,  C07C

CPC classification number: A01N37/44 ,  Y10S514/929

公开(公告)号：ZA746331B

公开(公告)日：1975-12-31

申请号：ZA746331

申请日：1974-10-04

Applicant: ABBOTT LAB

Inventor： OURS C ,  SOMANI P ,  JONES P ,  KUNCL J

IPC: A61K31/195 ,  A01N37/44 ,  A61K31/198 ,  A61K31/22 ,  A61P9/08 ,  C07C237/08 ,  A61K ,  C07C

Abstract: Covers the esters of gamma -glutamyl amide of dopamine selected from the group consisting of -CH2-CH2-NHO ¦ PARALLEL C-CH2-CH2-CH-C-OR PARALLEL ¦ ONH2 where R is a C1-C20 alkyl radical, and a pharmaceutically acceptable acid addition salt thereof. Also covers the use of said esters of gamma -glutamyl amide of dopamine to increase renal blood flow by administering said amide to warm-blooded mammals by clinically acceptable routes of administration such as oral, parenteral, rectal, etc.