公开(公告)号：AU511784B2

公开(公告)日：1980-09-04

申请号：AU2745377

申请日：1977-07-29

Applicant: ABBOTT LAB

Inventor： CARNEY R E ,  MCALPINE J B ,  PERUN T J

IPC: C07H15/236 ,  C07H15/22 ,  C07H15/26 ,  A61K31/71

Abstract: Described are novel derivatives of seldomycin factor 5 (XK-88-5) and particularly 3'-deoxyseldomycin factor 5, which exhibit improved activity against gram-positive and gram-negative bacteria resistant to aminoglycoside antibiotics, and a method of preparing them.

公开(公告)号：SE420999B

公开(公告)日：1981-11-16

申请号：SE7608452

申请日：1976-07-26

Applicant: ABBOTT LAB

Inventor： PERUN T J ,  RASMUSSEN R R ,  HORROM B W

IPC: C07D217/24 ,  A61K31/505 ,  A61P31/04 ,  C07D239/48 ,  C07D239/49

Abstract: This invention provides 2,4-diamino-5-benzylpyrimidines represented by the formula wherein R1 is H or loweralkyl; R2 is H, loweralkyl or R3CO- wherein R3 is H, alkyl, or cycloalkyl-lowerakyl; and X is a halogen; and the acid addition salts thereof.

公开(公告)号：SE7608452A

公开(公告)日：1977-02-01

申请号：SE7608452

申请日：1976-07-26

Applicant: ABBOTT LAB

Inventor： PERUN T J ,  RASMUSSEN R R ,  HORROM B W

IPC: C07D217/24 ,  A61K31/505 ,  A61P31/04 ,  C07D239/48 ,  C07D239/49

CPC classification number: C07D239/49 ,  C07D239/48

公开(公告)号：SE7608452L

公开(公告)日：1977-02-01

申请号：SE7608452

申请日：1976-07-26

Applicant: ABBOTT LAB

Inventor： PERUN T J ,  RASMUSSEN R R ,  HORROM B W

IPC: C07D217/24 ,  A61K31/505 ,  A61P31/04 ,  C07D239/48 ,  C07D239/49

Abstract: This invention provides 2,4-diamino-5-benzylpyrimidines represented by the formula wherein R1 is H or loweralkyl; R2 is H, loweralkyl or R3CO- wherein R3 is H, alkyl, or cycloalkyl-lowerakyl; and X is a halogen; and the acid addition salts thereof.

公开(公告)号：SE373134B

公开(公告)日：1975-01-27

申请号：SE592070

申请日：1970-04-29

Applicant: ABBOTT LAB

Inventor： JONES P H ,  PERUN T J

IPC: C07H17/08