公开(公告)号：ZA201103807B

公开(公告)日：2012-02-29

申请号：ZA201103807

申请日：2011-05-24

Applicant: ABBOTT LAB

Inventor： BRUNCKO MILAN ,  DING HONG ,  ELMORE STEVEN W ,  HEXAMER LAURA ,  MANTEI ROBERT A ,  PARK CHANG HEE ,  PETROS ANDREW J ,  SOUERS ANDREW J ,  TAO ZHI-FU ,  WANG LE ,  WENDT MICHAEL D ,  DAI YUJIA ,  DOHERTY GEORGE A ,  HASVOLD LISA A ,  KUNZER AARON R ,  MCCLELLAN WILLIAM J ,  PARK CHEOL-MIN ,  SONG XIAOHONG ,  SULLIVAN GERARD M ,  WANG GARY T ,  WANG XILU

IPC: A61K20060101 ,  A61P20060101 ,  C07D20060101

Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.