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公开(公告)号:ZA775652B
公开(公告)日:1979-04-25
申请号:ZA775652
申请日:1977-09-21
Applicant: ABBOTT LAB
Inventor: TADANIER J , MORI Y , SATO M , MARTIN J , KURATH P
IPC: A61K31/35 , A61K31/351 , C07D309/14 , A61K31/415 , A61P31/04 , C07D405/12 , C07H15/224 , A61K , C07C
Abstract: This invention provides 4-N-acylfortimicin B derivatives of the structure wherein R is acyl, aminoacyl, N-monoloweralkylaminoacyl, N,N-diloweralkylaminoacyl, hydroxy-substituted aminoacyl, or substituted aminoacyl of the formula where R1 is an acyl radical derived from an amino acid or a short peptide, and the pharmaceutically acceptable salts thereof.
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公开(公告)号:ZA764162B
公开(公告)日:1977-06-29
申请号:ZA764162
申请日:1976-07-13
Applicant: ABBOTT LAB
Inventor: SHIMIZU Y , SATO M , SUGIMOTO M , YAMAMOTO M , MORI Y , NARA T , OKACHI R
IPC: C07H15/224 , C12P1/06 , C12P19/48 , A61K
Abstract: A new antibiotic, Fortimicin C, is produced by fermentation of a microorganism belonging to the genus Micromonospora. The antibiotic is accumulated in the culture medium and is isolated therefrom.
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公开(公告)号:ZA7604162B
公开(公告)日:1977-06-29
申请号:ZA7604162
申请日:1976-07-13
Applicant: ABBOTT LAB
Inventor: SHIMIZU Y , SATO M , SUGIMOTO M , YAMAMOTO M , MORI Y , NARA T , OKACHI R
IPC: C07H15/224 , C12P1/06 , C12P19/48 , A61K
CPC classification number: C07H15/224 , Y10S435/863
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公开(公告)号:AU518301B2
公开(公告)日:1981-09-24
申请号:AU2902677
申请日:1977-09-22
Applicant: ABBOTT LAB
IPC: A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/7036 , A61K31/704 , A61P31/04 , C07H15/224 , C07H15/244 , C07H15/22 , A61K31/35
Abstract: The present invention relates to certain novel 4-N-substituted derivatives of the antibiotic Fortimicin B and processes for production thereof. Included in the process aspect of the invention, is a novel method for the semi-synthetic production of the antibiotic Fortimicin C.
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公开(公告)号:NZ185238A
公开(公告)日:1980-08-26
申请号:NZ18523877
申请日:1977-09-22
Applicant: ABBOTT LAB
IPC: A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/7036 , A61K31/704 , A61P31/04 , C07H15/224 , C07H15/244
Abstract: The present invention relates to certain novel 4-N-substituted derivatives of the antibiotic Fortimicin B and processes for production thereof. Included in the process aspect of the invention, is a novel method for the semi-synthetic production of the antibiotic Fortimicin C.
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公开(公告)号:AU507317B2
公开(公告)日:1980-02-14
申请号:AU1595276
申请日:1976-07-16
Applicant: ABBOTT LAB
Inventor: NARA T , MORI Y , SATO M , SUGIMOTO M , SHIMIZU Y , OKACHI R , YAMAMOTO M
IPC: C07H15/224 , C12P1/06 , C12P19/48 , C12D9/14 , C07H15/22
Abstract: A new antibiotic, Fortimicin C, is produced by fermentation of a microorganism belonging to the genus Micromonospora. The antibiotic is accumulated in the culture medium and is isolated therefrom.
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公开(公告)号:ZA7705652B
公开(公告)日:1979-04-25
申请号:ZA7705652
申请日:1977-09-21
Applicant: ABBOTT LAB
Inventor: TADANIER J , MORI Y , SATO M , MARTIN J , KURATH P
IPC: C07D309/14 , A61K31/35 , A61K31/351 , A61K31/415 , A61P31/04 , C07D405/12 , C07H15/224 , A61K , C07C
CPC classification number: C07H15/224
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8.
公开(公告)号:ZA775651B
公开(公告)日:1979-07-25
申请号:ZA775651
申请日:1977-09-21
Applicant: ABBOTT LAB
Inventor: MORI Y , TADANIER J , KURATH P , MARTIN J , SATO M
IPC: A61K31/35 , A61K31/351 , C07D309/14 , A61K31/415 , A61P31/04 , C07D405/12 , C07H15/224 , A61K , C07C
Abstract: This invention provides 4-N-acylfortimicin B derivatives of the structure wherein R is acyl, aminoacyl, N-monoloweralkylaminoacyl, N,N-diloweralkylaminoacyl, hydroxy-substituted aminoacyl, or substituted aminoacyl of the formula where R1 is an acyl radical derived from an amino acid or a short peptide, and the pharmaceutically acceptable salts thereof.
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9.
公开(公告)号:ZA7705651B
公开(公告)日:1979-07-25
申请号:ZA7705651
申请日:1977-09-21
Applicant: ABBOTT LAB
Inventor: MORI Y , TADANIER J , KURATH P , MARTIN J , SATO M
IPC: C07D309/14 , A61K31/35 , A61K31/351 , A61K31/415 , A61P31/04 , C07D405/12 , C07H15/224 , A61K , C07C
CPC classification number: C07H15/224
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