公开(公告)号：WO2008133753A2

公开(公告)日：2008-11-06

申请号：PCT/US2007/088027

申请日：2007-12-19

Applicant: ABBOTT LABORATORIES ,  BETEBENNER, David A. ,  MARING, Clarence J. ,  ROCKWAY, Todd W. ,  COOPER, Curt S. ,  ANDERSON, David D. ,  WAGNER, Rolf ,  ZHANG, Rong ,  MOLLA, Akhteruzzaman ,  MO, Hongmei ,  PILOT-MATIAS, Tami J. ,  MASSE, Sherie Vl. ,  CARRICK, Robert J. ,  HE, Wenping ,  LU, Liangjun

Inventor： BETEBENNER, David A. ,  MARING, Clarence J. ,  ROCKWAY, Todd W. ,  COOPER, Curt S. ,  ANDERSON, David D. ,  WAGNER, Rolf ,  ZHANG, Rong ,  MOLLA, Akhteruzzaman ,  MO, Hongmei ,  PILOT-MATIAS, Tami J. ,  MASSE, Sherie Vl. ,  CARRICK, Robert J. ,  HE, Wenping ,  LU, Liangjun

IPC: A61K31/675

CPC classification number: C07D471/04 ,  C07D239/94 ,  C07D487/04 ,  C07D487/14 ,  C07D519/00

Abstract: Compounds effective in inhibiting replication of Hepatitis C virus ( HCV ) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, coformulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.

Abstract translation: 公开了有效抑制丙型肝炎病毒（HCV）或其他病毒复制的化合物。 本发明还涉及包含这些化合物的组合物，这些化合物与其它抗病毒剂或治疗剂的共配制或共同给药，用于合成这些化合物的方法和中间体，以及使用这些化合物治疗HCV或 其他病毒感染。

公开(公告)号：EP1979349A2

公开(公告)日：2008-10-15

申请号：EP06848056.5

申请日：2006-12-20

Applicant: ABBOTT LABORATORIES

Inventor： ROCKWAY, Todd W. ,  BETEBENNER, David A. ,  KRUEGER, Allan C. ,  IWASAKI, Nobuhiko ,  COOPER, Curt S. ,  ANDERSON, David D. ,  KEMPF, Dale J. ,  MADIGAN, Darold L. ,  MOTTER, Christopher E. ,  SHANLEY, Jason P. ,  TUFANO, Michael D. ,  WAGNER, Rolf ,  ZHANG, Rong ,  MOLLA, Akhteruzzaman ,  MO, Hongmei ,  PILOT-MATIAS, Tami ,  MASSE, Sherie VL. ,  CARRICK, Robert J. ,  HE, Weping ,  LU, Liangjun

IPC: C07D471/04

CPC classification number: C07D471/04

Abstract: Compounds effective in inhibiting replication of Hepatitis C virus ('HCV') or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.

公开(公告)号：EP1979349B1

公开(公告)日：2010-07-28

申请号：EP06848056.5

申请日：2006-12-20

Applicant: ABBOTT LABORATORIES

Inventor： ROCKWAY, Todd W. ,  BETEBENNER, David A. ,  KRUEGER, Allan C. ,  IWASAKI, Nobuhiko ,  COOPER, Curt S. ,  ANDERSON, David D. ,  KEMPF, Dale J. ,  MADIGAN, Darold L. ,  MOTTER, Christopher E. ,  SHANLEY, Jason P. ,  TUFANO, Michael D. ,  WAGNER, Rolf ,  ZHANG, Rong ,  MOLLA, Akhteruzzaman ,  MO, Hongmei ,  PILOT-MATIAS, Tami ,  MASSE, Sherie VL. ,  CARRICK, Robert J. ,  HE, Weping ,  LU, Liangjun

IPC: C07D471/04

CPC classification number: C07D471/04

Abstract: Compounds effective in inhibiting replication of Hepatitis C virus ('HCV') or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.

公开(公告)号：EP2094276A2

公开(公告)日：2009-09-02

申请号：EP07874373.9

申请日：2007-12-19

Applicant: Abbott Laboratories

Inventor： BETEBENNER, David A. ,  MARING, Clarence J. ,  ROCKWAY, Todd W. ,  COOPER, Curt S. ,  ANDERSON, David D. ,  WAGNER, Rolf ,  ZHANG, Rong ,  MOLLA, Akhteruzzaman ,  MO, Hongmei ,  PILOT-MATIAS, Tami J. ,  MASSE, Sherie Vl. ,  CARRICK, Robert J. ,  HE, Wenping ,  LU, Liangjun

IPC: A61K31/675

CPC classification number: C07D471/04 ,  C07D239/94 ,  C07D487/04 ,  C07D487/14 ,  C07D519/00

Abstract: Compounds effective in inhibiting replication of Hepatitis C virus ( HCV ) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, coformulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.

Abstract translation: 公开了有效抑制丙型肝炎病毒（HCV）或其他病毒复制的化合物。 本发明还涉及包含此类化合物的组合物，这类化合物与其它抗病毒剂或治疗剂的共配制或共同施用，用于合成这些化合物的方法和中间体，以及使用此类化合物治疗HCV或 其他病毒感染。