公开(公告)号：WO2005110410A2

公开(公告)日：2005-11-24

申请号：PCT/US2005/016903

申请日：2005-05-13

Applicant: ABBOTT LABORATORIES ,  CUSACK, Kevin ,  SALMERON-GARCIA, Jose-Andres ,  GORDON, Thomas D. ,  BARBERIS, Claude E. ,  ALLEN, Hamish J. ,  BISCHOFF, Agniezka K. ,  ERICSSON, Anna M. ,  FRIEDMAN, Michael M. ,  GEORGE, Dawn M. ,  ROTH, Gregory P. ,  TALANIAN, Robert V. ,  THOMAS, Christine ,  WALLACE, Grier A. ,  WISHART, Neil ,  YU, Zhengtian

Inventor： CUSACK, Kevin ,  SALMERON-GARCIA, Jose-Andres ,  GORDON, Thomas D. ,  BARBERIS, Claude E. ,  ALLEN, Hamish J. ,  BISCHOFF, Agniezka K. ,  ERICSSON, Anna M. ,  FRIEDMAN, Michael M. ,  GEORGE, Dawn M. ,  ROTH, Gregory P. ,  TALANIAN, Robert V. ,  THOMAS, Christine ,  WALLACE, Grier A. ,  WISHART, Neil ,  YU, Zhengtian

IPC: A61K31/4743

CPC classification number: C07D471/04 ,  A61K31/4743 ,  C07D487/04 ,  C07D491/04 ,  C07D495/04 ,  Y02A50/481

Abstract: A compound or pharmaceutically acceptable salts thereof of Formula (I) wherein the substituents are as defined herein, which are useful as kinase inhibitors.

Abstract translation: 式（I）的化合物或其药学上可接受的盐，其中取代基如本文所定义，其可用作激酶抑制剂。

公开(公告)号：WO2007084728A3

公开(公告)日：2007-07-26

申请号：PCT/US2007/001548

申请日：2007-01-19

Applicant: ABBOTT LABORATORIES ,  ROTH, Gregory P. ,  WALLACE, Grier A. ,  GEORGE, Dawn M. ,  GRONGSAARD, Pintipa ,  HAYES, Martin ,  BREINLINGER, Eric C.

Inventor： ROTH, Gregory P. ,  WALLACE, Grier A. ,  GEORGE, Dawn M. ,  GRONGSAARD, Pintipa ,  HAYES, Martin ,  BREINLINGER, Eric C.

IPC: A61K31/496

Abstract: Novel compounds of Formula (I) or pharmaceutically acceptable salts, prodrugs and biologically active metabolites thereof of Formula (I), wherein the substituents are as defined herein, which are useful as therapeutic agents.

公开(公告)号：EP1753428A2

公开(公告)日：2007-02-21

申请号：EP05778736.8

申请日：2005-05-13

Applicant: ABBOTT LABORATORIES

Inventor： CUSACK, Kevin ,  SALMERON-GARCIA, Jose-Andres ,  GORDON, Thomas D. ,  BARBERIS, Claude E. ,  ALLEN, Hamish J. ,  BISCHOFF, Agnieszka K. ,  ERICSSON, Anna M. ,  FRIEDMAN, Michael M. ,  GEORGE, Dawn M. ,  ROTH, Gregory P. ,  TALANIAN, Robert V. ,  THOMAS, Christine ,  WALLACE, Grier A. ,  WISHART, Neil ,  YU, Zhengtian

IPC: A61K31/4743 ,  C07D498/02

CPC classification number: C07D471/04 ,  A61K31/4743 ,  C07D487/04 ,  C07D491/04 ,  C07D495/04 ,  Y02A50/481

Abstract: A compound or pharmaceutically acceptable salts thereof of Formula (I) wherein the substituents are as defined herein, which are useful as kinase inhibitors.

公开(公告)号：EP1983992A2

公开(公告)日：2008-10-29

申请号：EP07717989.3

申请日：2007-01-19

Applicant: ABBOTT LABORATORIES

Inventor： ROTH, Gregory P. ,  WALLACE, Grier A. ,  GEORGE, Dawn M. ,  GRONGSAARD, Pintipa ,  HAYES, Martin ,  BREINLINGER, Eric C.

IPC: A61K31/496

CPC classification number: C07D401/06 ,  C07D401/12 ,  C07D403/04 ,  C07D403/06 ,  C07D403/12 ,  C07D405/06 ,  C07D405/12 ,  C07D409/12 ,  C07D413/06 ,  C07D417/06 ,  C07D417/12 ,  C07D471/04 ,  C07D487/04

Abstract: Novel compounds of Formula (I) or pharmaceutically acceptable salts, prodrugs and biologically active metabolites thereof of Formula (I), wherein the substituents are as defined herein, which are useful as therapeutic agents.