公开(公告)号：AU2018358273A1

公开(公告)日：2020-05-07

申请号：AU2018358273

申请日：2018-10-24

Applicant: ADEKA CORP

Inventor： YAMAGUCHI YU ,  KIMURA TAKUYA

IPC: A61L27/36 ,  A61L27/50 ,  C07K14/78

Abstract: The present invention relates to a sheet-like decellularized material of biological material origin, wherein the maximum value of the tensile strengths in four directions is equal to or greater than 4 MPa, and the expansion rate in the direction in which the tensile strength reaches the maximum is 50% to 300%. The present invention provides a sheet-like material that is capable of maintaining a superior pressure resistance when used as a blood vessel or when used to repair a blood vessel.

公开(公告)号：CA2987723A1

公开(公告)日：2016-12-08

申请号：CA2987723

申请日：2016-05-31

Applicant: ADEKA CORP

Inventor： HIWATARI KEN-ICHIRO ,  YAMAGUCHI YU ,  KIMURA TAKUYA ,  TASAKI AKIKO

IPC: A61F2/06 ,  A61L27/00

Abstract: The purpose of the present invention is to provide a sheet derived from a biological tissue, which can be used for the production of a tubular structure that can be used in an artificial blood vessel and has excellent pressure resistance and handling properties. For the purpose of achieving the purpose, the present invention provides: a sheet of a biological tissue, in which the edge part of at least one side has a tapered shape that becomes thin in the thickness direction toward the end of the edge part; a tubular structure produced from the sheet; and an artificial blood vessel comprising the tubular structure.

公开(公告)号：HK1247077A1

公开(公告)日：2018-09-21

申请号：HK18106721

申请日：2018-05-24

Applicant: ADEKA CORP

Inventor： HIWATARI KEN-ICHIRO ,  YAMAGUCHI YU ,  KIMURA TAKUYA ,  TASAKI AKIKO

IPC: A61F20060101 ,  A61L20060101

公开(公告)号：CA3084334A1

公开(公告)日：2019-05-09

申请号：CA3084334

申请日：2018-10-24

Applicant: ADEKA CORP

Inventor： YAMAGUCHI YU ,  KIMURA TAKUYA

IPC: A61L27/36 ,  A61L27/50 ,  C07K14/78

Abstract: The present invention relates to a sheet-like decellularized material of biological material origin, wherein the maximum value of the tensile strengths in four directions is equal to or greater than 4 MPa, and the expansion rate in the direction in which the tensile strength reaches the maximum is 50% to 300%. The present invention provides a sheet-like material that is capable of maintaining a superior pressure resistance when used as a blood vessel or when used to repair a blood vessel.

公开(公告)号：CA3065498A1

公开(公告)日：2018-12-06

申请号：CA3065498

申请日：2018-05-25

Applicant: ADEKA CORP

Inventor： HIGAMI TETSUYA ,  HIWATARI KENICHIRO ,  YAMAGUCHI YU ,  OBARA HARUKI ,  KIMURA TAKUYA ,  HOMMA MITSUMASA ,  OCHIAI KYOHEI ,  KINOSHITA KEITA ,  MORIMOTO NAOKI

IPC: A61L27/36 ,  A61F2/06

Abstract: The purpose of the present invention is to provide a method for producing a decellularized material for transplantation that can be used in a graft composition and minimizes the portion sutured by thread. To achieve the above purpose, the present invention provides a method for producing a decellularized material for transplantation that includes (a) a step for collecting a branched blood vessel from a vertebrate animal (donor), (b) a step for decellularizing the blood vessel, and (c) a step for adhering the portion from which the branch has been excised by protein denaturation treatment and closing the vessel. The present invention also provides a graft composition comprising a biocompatible material that includes the decellularized material for transplantation.