公开(公告)号：JPH0892203A

公开(公告)日：1996-04-09

申请号：JP23284694

申请日：1994-09-28

Applicant: AGENCY IND SCIENCE TECHN

Inventor： TSUCHIYA TORU ,  SHIBUYA ISAO ,  TAGUCHI YOICHI ,  OISHI AKIHIRO ,  HONDA KAZUMASA

IPC: C07D223/08 ,  C07C327/42 ,  C07C327/44 ,  C07D223/02 ,  C07D223/06 ,  C07D225/02

Abstract: PURPOSE: To provide a new β-ketothioamide derivative useful as a chelating reagent or an intermediate for organic synthesis and easily producible by a new reaction of an N,N-disubstituted amide with a bis(trialkylsilyl)thioketene. CONSTITUTION: This β-ketothioamide derivative is expressed by formula I (R and R are each a hydrocarbon group; R is H or a hydrocarbon group; R may be bonded with R or R to form a ring structure), e.g. N,N-dimethyl-3- oxothiobutyramide of formula II. The compound of formula I can be produced by reacting an N,N-disubstituted amide of formula III with a bis(trialkylsilyl) thioketene and treating the reaction product with an alcohol. The β- ketothioamide derivative can be produced by this production process with a simple procedure under mild reaction condition in high yield using an inexpensive raw material.

公开(公告)号：JP2000072757A

公开(公告)日：2000-03-07

申请号：JP23786798

申请日：1998-08-25

Applicant: AGENCY IND SCIENCE TECHN

Inventor： SHIBUYA ISAO ,  GAMA YASUO ,  SHIMIZU MASAO ,  HONDA KAZUMASA

IPC: C07D251/20 ,  C07D251/46 ,  C07D405/04

Abstract: PROBLEM TO BE SOLVED: To efficiently obtain the subject compound useful as an intermediate for fine chemical products such as medicines and agrochemicals from easily available compounds as raw materials by a simple operation comprising reacting a thiocarbamoyl compound with silver cyanate. SOLUTION: This method for producing a 1,6-disubstituted-1,3,5-triazine-2,4(1 H,3H)-dione compound of formula II, for example, 1,6-diphenyl-1,3,5-triazine-2,4(1 H,3H)-dione, etc., comprises reacting (A) a thiocarbamoyl compound of formula I [Z is-R2,-NHR2, or-N(R2)2(R2 is an organic group); R1 is an organic group] with (B) silver cyanide. The component A is preferably thiobenzoyl anilide, etc., and the component B is preferably used in an amount of >=2 equivalents per mole of the component A. The reaction is preferably carried out in an organic solvent such as acetonitrile.

公开(公告)号：JP2000065763A

公开(公告)日：2000-03-03

申请号：JP23585798

申请日：1998-08-21

Applicant: SHIMADZU CORP ,  AGENCY IND SCIENCE TECHN

Inventor： HONDA KAZUMASA ,  KOJIMA ISAO ,  HIROSE HIDEO ,  HAYASHI SHIGEKI

IPC: G01N23/22 ,  G21K1/06

Abstract: PROBLEM TO BE SOLVED: To obtain an X-ray analyzer by which the intensity distribution of the wavelength of X-rays is measured in a short time and with a small time difference. SOLUTION: By using a plurality of crystal planes which are provided at one dispersive crystal, X-rays are spectrally diffracted into a plurality of different wavelengths. In addition, by using a two-dimensional detector, the X-rays at a plurality of spectrally diffracted different wavelengths are distinguished and detected. As a first mode, in an X-ray analyzer in which a spectrscope is irradiated with X-rays and in which an X-ray analysis is performed by the X-rays, at a specific wavelength, which are spectrally diffracted by the spectrscope, the spectroscope uses a plurality of crystal planes whose lattice spacing and orientation are provided in one crystal at a dispersive crystal 1 provided at the spectroscope are different, and the X-rays are spectrally diffracted simultaneously into a plurality of different wavelengths by a plurality of crystal planes at the dispersive crystal 1. As a second mode, an X-ray analyzer is constituted in such a way that a spectroscope provided with a plurality of crystal planes whose lattice spacing and orientation are different in one crystal is provided and that a two-dimensional detector 20 which detects the intensity and the incident position of X-rays is provided. The X-rays are spectrally diffracted simultaneously into a plurality of different wavelengths by using the plurality of crystal planes, and a plurality of spectrally diffracted X-rays are detected simultaneously by the two-dimensional detector 20.

公开(公告)号：JPH1045719A

公开(公告)日：1998-02-17

申请号：JP11051997

申请日：1997-04-28

Applicant: AGENCY IND SCIENCE TECHN

Inventor： TSUCHIYA TORU ,  SHIBUYA ISAO ,  TAGUCHI YOICHI ,  OISHI AKIHIRO ,  HONDA KAZUMASA

IPC: C07D223/08 ,  C07D225/02 ,  C09K3/00

Abstract: PROBLEM TO BE SOLVED: To easily obtain a new cyclic β-ketothioamide derivative having a chelating effect and a cyclic structure and useful as a separating agent or a recovering agent of a metal, a synthesis intermediate for various kinds of thioamide derivatives having substituted group at β-position, etc. SOLUTION: This cyclic β-ketothioamide derivative is represented by formula I (R is a hydrocarbon; A is a divalent hydrocarbon allowing O, S or N to intervene), e.g. N-methyl-3-oxo-ε-thiocaprolactam. The derivative of formula I is obtained by reacting a N-substituted lactam of formula II e.g. 1- methylpyrrolidin-2-one} with a bis(trialkylsilyl)thioketene of formula III (R , R and R are each an alkyl) and thereafter treating the reaction product with an alcohol.