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公开(公告)号:DE69516446T2
公开(公告)日:2000-12-14
申请号:DE69516446
申请日:1995-02-28
Applicant: AGENCY IND SCIENCE TECHN
Inventor: TAGUCHI YOICHI , OISHI AKIHIRO , SHIBUYA ISAO , TSUCHIYA TOHRU
IPC: A01N43/90 , C07D491/04 , C07D491/048 , A61K31/395
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公开(公告)号:DE69516446D1
公开(公告)日:2000-05-31
申请号:DE69516446
申请日:1995-02-28
Applicant: AGENCY IND SCIENCE TECHN
Inventor: TAGUCHI YOICHI , OISHI AKIHIRO , SHIBUYA ISAO , TSUCHIYA TOHRU
IPC: A01N43/90 , C07D491/04 , C07D491/048 , A61K31/395
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公开(公告)号:DE69107579T2
公开(公告)日:1995-06-14
申请号:DE69107579
申请日:1991-11-15
Applicant: AGENCY IND SCIENCE TECHN
Inventor: YASUMOTO MASAHIKO , TSUCHIYA TOURU , SHIBUYA ISAO , YONEMOTO KATSUMI , TAGUCHI YOICHI C O NATIONAL CH
IPC: C07D285/34
Abstract: There is disclosed a method for producing 2,6-bis(disubstituted amino)-4-1,3,5-thiadiazine-4-one compounds represented by formula (I). The method comprises reacting an N,N-disubstituted cyanamide represented by formula (II) with carbonyl sulfide represented by formula (III) under a high pressure. wherein R1 and R2 each represent an alkyl group or R1 and R2 may bond together to form a ring, wherein R1 and R2 each have the same meanings as in formula (I), Formula (III> S = C = O . o
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公开(公告)号:DE69107579D1
公开(公告)日:1995-03-30
申请号:DE69107579
申请日:1991-11-15
Applicant: AGENCY IND SCIENCE TECHN
Inventor: YASUMOTO MASAHIKO , TSUCHIYA TOURU , SHIBUYA ISAO , YONEMOTO KATSUMI , TAGUCHI YOICHI C O NATIONAL CH
IPC: C07D285/34
Abstract: There is disclosed a method for producing 2,6-bis(disubstituted amino)-4-1,3,5-thiadiazine-4-one compounds represented by formula (I). The method comprises reacting an N,N-disubstituted cyanamide represented by formula (II) with carbonyl sulfide represented by formula (III) under a high pressure. wherein R1 and R2 each represent an alkyl group or R1 and R2 may bond together to form a ring, wherein R1 and R2 each have the same meanings as in formula (I), Formula (III> S = C = O . o
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公开(公告)号:JP2000072792A
公开(公告)日:2000-03-07
申请号:JP24390898
申请日:1998-08-28
Applicant: AGENCY IND SCIENCE TECHN
Inventor: GAMA YASUO , SHIBUYA ISAO , SHIMIZU MASAO
IPC: C07H19/12
Abstract: PROBLEM TO BE SOLVED: To obtain the subject novel N-glycoside that is useful as a physiologically active compound or its intermediate compound from a readily available raw material. SOLUTION: This novel compound is an N-glycoside represented by formula I (Z is 2,3,4,6-tetra-O-acetyl-β-D-gluco-pyranosyl; R1 and R2 are each an alkyl, an aryl, an aralkyl or the like), typically 1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-6- diethylamino-1,3,5-triazine-2,4-dione. The compound of formula I is readily prepared in high yield, for example, by allowing silver cyanate to react with an N-glycosyl-N',N'-disubstituted thiourea represented by formula II (Z1 is 2,3,4,6- tetra-O-acetyl-β-D-glucopyranosyl). The compound of formula I is useful as an intermediate for fine chemical products as medicines, agrochemicals and the like or as a physiologically active substance.
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公开(公告)号:JPH0527359A
公开(公告)日:1993-02-05
申请号:JP4410991
申请日:1991-02-18
Applicant: AGENCY IND SCIENCE TECHN , KONISHIROKU PHOTO IND
Inventor: YONEMOTO KATSUMI , SHIBUYA ISAO , HIRABAYASHI SHIGETO , KANEKO YUTAKA
IPC: G03C1/34
Abstract: PURPOSE:To prevent fogging and to suppress fogging at the time of rapid processing at high temp. by using a specified compd. as an anti-foggant. CONSTITUTION:A compd. represented by formula I is used as an anti-foggant for silver halide photography. In the formula I, each of R1 and R2 is alkyl, R1 and R2 may be different from each other and R3 is alkoxy or dialkylamino. At least one kind of anti-foggant made of the compd. represented by the formula I is incorporated into a silver halide emulsion layer or an adjacent hydrophilic colloidal layer. This anti-foggant inhibits fogging during storage even at high temp. or high temp. and humidity and does not cause the lowering of sensitivity and the softening of gradation.
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公开(公告)号:JPH03261747A
公开(公告)日:1991-11-21
申请号:JP6080090
申请日:1990-03-12
Applicant: AGENCY IND SCIENCE TECHN
Inventor: YASUMOTO MASAHIKO , GOTO MIDORI , TSUCHIYA TORU , SHIBUYA ISAO
IPC: C07D295/02 , C07B43/04 , C07C209/22 , C07C211/63 , C07C211/64 , C07D213/20
Abstract: NEW MATERIAL:A thiocyanate of quaternary ammonium shown by formula I (R1 is alkyl or aralkyl; R2 to R4 are alkyl, aralkyl, aryl or mutually formed to give group as shown by formula II or formula III). EXAMPLE:Benzyltriethylammonium thiocyanate. USE:A surfactant, catalyst, drug and an intermediate thereof. PREPARATION:A thiocyanate shown by formula IV is reacted with a tertiary amine shown by formula V under normal pressure or high pressure to give a compound shown by formula I. By this method, the compound is obtained by using inexpensive raw materials by one stage in high yield.
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公开(公告)号:JPH03258768A
公开(公告)日:1991-11-19
申请号:JP5577990
申请日:1990-03-07
Applicant: AGENCY IND SCIENCE TECHN
Inventor: TAGUCHI YOICHI , SHIBUYA ISAO
IPC: C07D251/38 , A01N43/64
Abstract: PURPOSE:To simply prepare a 1,3,5-perhydrotriazine-2,4,6-trithione derivative in a high yield by reacting an isothiocyanic acid ester in the presence of a base under a high pressure. CONSTITUTION:An isothiocyanic acid ester of formula RNCS (R is alkyl, aryl) is reacted with in the presence of a base such as triethylamine in a solvent such as benzene at room temperature to 100 deg.C under a high pressure of 500-9000kg/cm to provide the objective compound. 1,3,5-Trimethyl-1,3,5- perhydrotrithione is active to diseases of rice and an oxygen homologue thereof, an isocyanuric acid derivative, is useful as a modifying agent for resins, etc.
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公开(公告)号:JPS63221171A
公开(公告)日:1988-09-14
申请号:JP5479087
申请日:1987-03-10
Applicant: AGENCY IND SCIENCE TECHN
Inventor: YASUMOTO MASAHIKO , YANAGIYA KOSHIN , SHIBUYA ISAO , SEKIGUCHI TATSUO
Abstract: PURPOSE:To obtain the title compd. which is a colorless crystal and has a high purity in a high yield without causing environmental pollution, by subjecting an arom. aldehyde and an arom. diamine to a dehydration-condensation reaction in the presence of optionally, a small amount of a reaction accelerator under high pressure. CONSTITUTION:An arom. aldehyde (A) such as benzaldehyde or a dialkylamino-, alkoxy-, alkyl-, NO2 or halogen-substd. benzaldehyde and an arom. amine (B) such as N,N-dialkylaniline, N-alkylaniline, aniline or a substitution compd. thereof are subjected to a dehydration-condensation reaction in the presence of a optionally, 0.1-50mol.% (based on the amount of the component A) of a reaction accelerator such as protonic acid, Lewis acid, etc. under a high pressure of 1,000-9,000kg/cm .
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公开(公告)号:JPS63218672A
公开(公告)日:1988-09-12
申请号:JP5274887
申请日:1987-03-07
Applicant: AGENCY IND SCIENCE TECHN
Inventor: TAGUCHI YOICHI , YANAGIYA KOSHIN , SHIBUYA ISAO , SUHARA YASUO
IPC: C07D327/04 , B01J31/02 , C07B61/00 , C07D339/06
Abstract: PURPOSE:To obtain the titled substance useful as a synthetic intermediate for tetrathiafulvalene which is a charge-transfer complex, intermediate material for physiologically active substance or the like in one stage and good yield, by reacting an epoxide with CS2 in the presence of a base under high pressure. CONSTITUTION:An epoxide expressed by formula I (R is alkyl or aryl; R and R are alkyl or H) is reacted with CS2 in the presence of a base (preferably tert. amine) at high pressure of 500-9,000kg/cm2 and room temperature - 120 deg.C for 5-50hr to provide the aimed compounds expressed by formula II and formula III.
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