公开(公告)号：US3895040A

公开(公告)日：1975-07-15

申请号：US29772772

申请日：1972-10-16

Applicant: AGENCY IND SCIENCE TECHN

Inventor： MIYAZAKI SHOJI ,  SUHARA YASUO

IPC: C07C51/235 ,  C07C51/245 ,  C08H17/36

CPC classification number: C07C51/245 ,  C07C51/235 ,  C07C55/10 ,  C07C53/126 ,  C07C55/21 ,  C07C53/124 ,  C07C53/122 ,  C07C55/02 ,  C07C55/18 ,  C07C55/20

Abstract: An Alpha , omega -glycol, a primary alcohol or an aliphatic compound having one or two secondary alcohol groups is dissolved in a solvent. The resulting solution is heated to 10* - 70*C and brought into contact with an ozone-containing gas. Then, the solution is elevated to 70* - 110*C and brought into contact with an oxygen-containing gas. By thus oxidizing the starting material, there is formed in the solution a dibasic acid or a fatty acid; the former acid occurs where the starting material being used is an Alpha , omega -glycol and the latter acid occurs where it is either a primary alcohol or an aliphatic compound having one or two secondary alcohol groups. The dibasic acid or fatty acid thus formed within the solution can be isolated by removing the solvent from the solution.

Abstract translation: 将α，ω-二醇，伯醇或具有一个或两个仲醇基团的脂肪族化合物溶解在溶剂中。 将所得溶液加热至10〜70℃，与含臭氧气体接触。 然后，将溶液升温至70〜110℃，与含氧气体接触。 通过这样氧化原料，在溶液中形成二元酸或脂肪酸; 在使用起始原料为α，ω-二醇的情况下，发生前者酸，后者在其中是伯醇或具有一个或两个仲醇基团的脂族化合物的情况下发生。 通过从溶液中除去溶剂，可以分离溶液中形成的二元酸或脂肪酸。

公开(公告)号：JPH0296547A

公开(公告)日：1990-04-09

申请号：JP24901388

申请日：1988-10-04

Applicant: AGENCY IND SCIENCE TECHN ,  NIPPON KASEI CHEM

Inventor： SUHARA YASUO ,  MIYAZAKI SHOJI ,  TACHIBANA SHUICHI ,  SUZUKI TAKESHI ,  KENBO NAOYA

IPC: C07D307/60 ,  A01N37/04 ,  C07C51/34 ,  C07C55/24 ,  C07C67/313 ,  C07C69/34 ,  C09K3/16 ,  C23F11/12

Abstract: PURPOSE:To effectively suppress formation of impurities and obtain the objective compound in high purity by setting a blowing rate of ozone within a specific range in oxidizing a fatty acid derivative having cyclohexane ring with ozone and producing the subject compound. CONSTITUTION:A raw material consisting of a compound expressed by formula I (n and m are integers of 4-10; X is H or 1-4C alkyl; A and B are COOX or both may form acid anhydride) is oxidized with ozone to produce a compound expressed by formula II useful as a rust inhibitor, germicide, antistatic agent or intermediate therefor. In the process, blowing rate of the ozone is regulated to

公开(公告)号：JPS63112622A

公开(公告)日：1988-05-17

申请号：JP25949486

申请日：1986-10-30

Applicant: AGENCY IND SCIENCE TECHN

Inventor： SUZUKI HIROSHI ,  MIYAZAKI SHOJI ,  GAMA YASUO ,  SUHARA YASUO

IPC: B01F17/00 ,  B01F17/42 ,  B01F17/52 ,  C08G65/32 ,  C09K3/16 ,  C11D1/08

Abstract: PURPOSE:To obtain the title derivative useful as a surfactant excellent in emulsifying power, dispersing power, chelating power, surface tension depressing power, corrosion-inhibiting power, antibacterial activity, etc., having a specified structural formula. CONSTITUTION:A cyclohexene ring-containing aliphatic derivative of formula I or II (wherein R and R' are each H or an alkyl) and glacial acetic acid are ozonized at 10-14 deg.C in the presence of an ozone/oxygen mixture, and the formed ozonide is decomposed and then oxidized to obtain a compound (a), which is an acid or a partial alkyl ester, of formula III (wherein n and n' are each 4-15, Y is H or COOR and R is H or a 1-18C alkyl, provided that at least one of them is H). Component (a) is esterified with a polyalkylene glycol (b) (PAG) of a degree of polymerization of 1-20 and the product is neutralized or saponified to obtain a tetra- or penta-carboxylic acid derivative of formula IV [wherein X is H or COOA, A is a PAG residue of formula V (wherein m is 2-4 and p is 1-20), H, a 1-18C alkyl, an alkali metal, or an (alkanol) ammonium ion, and at least one X is a PAG residue].

公开(公告)号：JPH01230574A

公开(公告)日：1989-09-14

申请号：JP5719788

申请日：1988-03-10

Applicant: AGENCY IND SCIENCE TECHN

Inventor： TAGUCHI YOICHI ,  SHIBUYA ISAO ,  SUHARA YASUO

IPC: C07D339/06

Abstract: PURPOSE:To obtain the subject compound useful as a raw material for a dye for the dyeing of paper or pulp, in one step and high yield without using deadly poisonous phosgene, etc., by using easily available epoxide and carbon disulfide as raw materials and reacting the components in the presence of a base under high pressure. CONSTITUTION:The objective compound of formula II can be produced by reacting an epoxide of formula I (R is alkyl or aryl; R is alkyl or H) with carbon disulfide in the presence of a base (e.g., triethylamine or pyridine) under high pressure. The reaction pressure is preferably as high as possible and is usually 500-9,000kg/cm . The reaction is carried out at room temperature -120 deg.C for usually 5-50hr. The reaction solvent is hexane, benzene, etc., and the compound of formula I is used in an amount nearly equimolar to the amount of the carbon disulfide.

公开(公告)号：JPS63218672A

公开(公告)日：1988-09-12

申请号：JP5274887

申请日：1987-03-07

Applicant: AGENCY IND SCIENCE TECHN

Inventor： TAGUCHI YOICHI ,  YANAGIYA KOSHIN ,  SHIBUYA ISAO ,  SUHARA YASUO

IPC: C07D327/04 ,  B01J31/02 ,  C07B61/00 ,  C07D339/06

Abstract: PURPOSE:To obtain the titled substance useful as a synthetic intermediate for tetrathiafulvalene which is a charge-transfer complex, intermediate material for physiologically active substance or the like in one stage and good yield, by reacting an epoxide with CS2 in the presence of a base under high pressure. CONSTITUTION:An epoxide expressed by formula I (R is alkyl or aryl; R and R are alkyl or H) is reacted with CS2 in the presence of a base (preferably tert. amine) at high pressure of 500-9,000kg/cm2 and room temperature - 120 deg.C for 5-50hr to provide the aimed compounds expressed by formula II and formula III.

公开(公告)号：JPS62207268A

公开(公告)日：1987-09-11

申请号：JP4936686

申请日：1986-03-06

Applicant: AGENCY IND SCIENCE TECHN

Inventor： TAGUCHI YOICHI ,  YANAGIYA KOSHIN ,  SHIBUYA ISAO ,  SUHARA YASUO

IPC: C07D339/06

Abstract: PURPOSE:To obtain the titled compound useful as an intermediate for tetrathiafulvalene (electric charge transfer complex) or an intermediate substance for physiological active substance simply and in high yield, by reacting thiirane compound with carbon disulfide in the presence of a base at a high temperature. CONSTITUTION:A thiirane compound shown by formula I (R is alkyl or aryl; R and R are alkyl or H) is reacted with carbon disulfide in the presence of a base such as tertiary amine, e.g. triethylamine, pyridine, etc. at high pressure of 500-9,000kg/cm at room temperature -100 deg.C to give the aimed compound shown by formula II in high yield and efficiently. The compound shown by formula I can be readily synthesized from a corresponding epoxide and thiourea or potassium thiocyanate and carbon dioxide is inexpensively sold on the market.

公开(公告)号：JPS6293252A

公开(公告)日：1987-04-28

申请号：JP23506785

申请日：1985-10-21

Applicant: AGENCY IND SCIENCE TECHN

Inventor： SUZUKI HIROSHI ,  MIYAZAKI SHOJI ,  GAMA YASUO ,  SUHARA YASUO

IPC: C07C69/34 ,  C07C51/00 ,  C07C55/24 ,  C07C67/00 ,  C09K3/16

Abstract: NEW MATERIAL:An amine salt of a tetra- or pentacarboxylic acid expressed by formula I [n and n' are 4-10; X is H or COOZ (Z is H, alkyl or substituted ammonium ion and at least one thereof is substituted ammonium ion)]. EXAMPLE:Pentamonoethanolamine salt of 1,9,10,12-octadecanepentacarboxylic acid. USE:An economical antistatic agent, having improved antistatic effect and good durability and low toxicity and capable of exhibiting effect in a low concentration. The agent has a wide range of solubility in water, oil and plastics, scarcely colors an object since it is colorless or light yellow and can be used for cloth, plastics, etc., by external coating, spraying or internal incorporation without trouble by harshness because of low foaming property. PREPARATION:An acid expressed by formula II (Y is H or COOH) is neutralized with an amine, e.g. aliphatic amine or aliphatic alkylolamine, etc., to afford the aimed compound expressed by formula I.

公开(公告)号：JPS6219582A

公开(公告)日：1987-01-28

申请号：JP15952585

申请日：1985-07-19

Applicant: AGENCY IND SCIENCE TECHN

Inventor： TAGUCHI YOICHI ,  SUHARA YASUO

IPC: C07D333/32 ,  C07D333/38 ,  C07D333/68

Abstract: PURPOSE:To obtain simply in high yield a compound useful as a germicide, an anti-inflammatory agent, an activator for polymerization, etc., by reacting thiirane with an active methylene compound in the presence of a strong base. CONSTITUTION:A thiirane shown by the formula I (R is alkyl, aryl, or H; R and R are alkyl or H) is reacted with an active methylene compound shown by the formula II (R is alkyl; R is alkyl or alkoxy) in the presence of a base (e.g., sodium ethoxide) in a solution of an alkali catalyst (e.g., sodium hydride) in a solvent such as ethanol, etc., at room temperature or under heating to give the aimed compound shown by the formula III or formula IV. The compound shown by the formula I is easily synthesized from a corresponding epoxide by the use of thiourea or potassium thiocyanate and the compound shown by the formula II is inexpensively on the market and easily obtainable.