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公开(公告)号:DE3843534A1
公开(公告)日:1990-07-12
申请号:DE3843534
申请日:1988-12-23
Applicant: BASF AG
Inventor: DAUM LOTHAR DR , DOERPER THOAMS DR , HILLEN HEINZ DR , MOELLER ACHIM DR , SCHOLLMEIER KLAUS DR , WALKER NIGEL DR , KEILHAUER GERHARD DR
IPC: A61K38/00 , C07K14/525 , C12N1/21 , C12N15/28
Abstract: Polypeptides derived from tumour necrosis factors (TNF) differ from natural TNF by the substitution and/or deletion of amino acids. These novel polypeptides are useful therapeutic agents.