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公开(公告)号:DE19717191A1
公开(公告)日:1998-10-29
申请号:DE19717191
申请日:1997-04-24
Applicant: BASF AG
Inventor: ERNST ANDREAS DR , BREITENBACH JOERG DR , SANNER AXEL DR
Abstract: The invention relates to a method for producing liquid iodophors from poly-n-vinyl lactams and dextrines as carrier materials, characterized in that a mixture of the carrier materials, iodine and iodide ions, or a reducing agent instead of iodide ions, is heated in an aqueous medium in the presence of a mono or polyvalent alcohol with 1 to 6 C atoms at a temperature ranging from 40 to 100 DEG C.
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公开(公告)号:DE19753300A1
公开(公告)日:1999-06-02
申请号:DE19753300
申请日:1997-12-01
Applicant: BASF AG
Inventor: KOTHRADE STEPHAN DR , BERNDL GUNTHER DR , ERNST ANDREAS DR , SANNER AXEL DR
IPC: A61K9/14 , A61K9/16 , A61K9/20 , A61K47/32 , A61K31/275
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公开(公告)号:ES2247992T3
公开(公告)日:2006-03-16
申请号:ES00117131
申请日:2000-08-10
Applicant: BASF AG
Inventor: ERNST ANDREAS DR , KESSLER THOMAS , BERNDL GUNTHER DR
IPC: A01N25/10 , A01N25/12 , A23K40/10 , A23K40/20 , A23L33/15 , A23L33/155 , A23P1/02 , A61J3/00 , A61K9/16 , A61K9/19 , A61K47/32 , B01J2/20 , B29B9/06 , C08J3/205 , C08J3/12 , A61K9/20 , A61J3/10
Abstract: Procedimiento para la obtención de granulados que contienen substancias con actividad biológica, que se emplean para la obtención de medicamentos, piensos, complementos alimenticios y agentes dietéticos, en los que las substancias con actividad biológica se presentan dispersadas de manera homogénea en una matriz a base de al menos un polímero elaborable como termoplástico, que presenta una solubilidad dependiente del valor de pH en medio acuoso, mediante mezclado homogéneo de substancias de empleo en la fusión y subsiguiente extrusión y conformado, caracterizado porque el conformado se efectúa en un medio refrigerante, en el que los granulados no son solubles o dispersables, empleándose como medio refrigerante agua, cuyo valor de pH es ajustable de modo que los granulados no sean solubles o dispersables.
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公开(公告)号:DK1083196T3
公开(公告)日:2005-11-21
申请号:DK00117131
申请日:2000-08-10
Applicant: BASF AG
Inventor: KESSLER THOMAS , ERNST ANDREAS DR , BERNDL GUNTHER DR
IPC: A01N25/10 , A01N25/12 , A23K40/10 , A23K40/20 , A23L33/15 , A23L33/155 , A23P1/02 , A61J3/00 , A61K9/16 , A61K9/19 , A61K47/32 , B01J2/20 , B29B9/06 , C08J3/205 , C08J3/12 , A61J3/10 , A61K9/20
Abstract: Production of granules comprising biologically active substances (I) dispersed in a thermoplastic polymer matrix having pH-dependent solubility in aqueous media comprises mixing (I) with the molten matrix material and extruding the melt into a coolant medium in which the granules are not soluble or dispersible An Independent claim is also included for granules produced by the process.
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公开(公告)号:DE19753299A1
公开(公告)日:1999-06-02
申请号:DE19753299
申请日:1997-12-01
Applicant: BASF AG
Inventor: KOTHRADE STEPHAN DR , ERNST ANDREAS DR , SANNER AXEL DR
IPC: A01N25/14 , A23K20/10 , A23K40/10 , A23K40/20 , A23L27/00 , A23L33/10 , A61K9/20 , A61K31/167 , A61K31/277 , A61K47/32 , A23K1/16 , A23L1/29 , A61K31/275
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公开(公告)号:DE19753298A1
公开(公告)日:1999-06-02
申请号:DE19753298
申请日:1997-12-01
Applicant: BASF AG
Inventor: KOTHRADE STEPHAN DR , MEFFERT HELMUT DR , BERNDL GUNTHER DR , ERNST ANDREAS DR , SANNER AXEL DR
IPC: A61K47/32 , A23K20/10 , A23K40/10 , A23K40/20 , A23L27/00 , A23L33/10 , A61K9/16 , A61K9/20 , A61K9/22 , A61K31/277 , A61K31/421 , A61K31/275 , A23K1/16 , A23L1/29
Abstract: The invention relates to a method for producing solid dosing forms by mixing at least one polymeric binding agent, at least one active substance, and optional common additives while producing a plastic mixture and during shaping, whereby a copolymer from a N-vinyl lactam and from an copolymerizable monomer with a hydrophobic radical is used as a polymeric binding agent. Dosing forms which slowly release the active substance are obtained in a simple and economical manner.
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