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公开(公告)号：AU3032497A
公开(公告)日：1998-01-07
申请号：AU3032497
申请日：1997-06-05
Applicant: BASF AG
Inventor： MERKLE HANS RUPERT , FRETSCHNER ERICH , HOFMANN JURGEN , JAGER KARL-FRIEDRICH , DIENER RALPH , HARTL AXEL PAUL , SCHONHERR MICHAEL
Abstract: A process for the production of alkaline metal salts and earth alkali metal salts of aryloxy-C1-C4-alkane carboxylic acids by reacting the basic aryloxy-C1-C4-alkane carboxylic acids with alkaline metal bases or earth alkali metal bases in the melt, by extruding a mixture of the aryloxy-C1-C4-alkane carboxylic acid and an at least stoichiometric quantity of an alkaline metal base or an earth alkali metal base, which are partially or completely converted in the reaction conditions into volatile substances. The invention also concerns the extrudates thus obtainable and the use of the extrudates which contain an aryloxy-C1-C4-alkane carboxylic acid with herbicidal action to combat undesired plant growth.
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公开(公告)号：ID16634A
公开(公告)日：1997-10-23
申请号：ID963037
申请日：1996-10-23
Applicant: BASF AG
Inventor： BREITENBACH JORG , HARTL AXEL PAUL , HOFMANN JURGEN , ROSENBERG JOERG , SCHIEBL MICHAEL , ZETTLER HANS DIETER
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3.发明专利
公开(公告)号：AU706859B2
公开(公告)日：1999-06-24
申请号：AU7491296
申请日：1996-10-23
Applicant: BASF AG
Inventor： BREITENBACH JORG , HARTL AXEL PAUL , HOFMANN JURGEN , ROSENBERG JOERG , SCHIESSL MICHAEL , ZETTLER HANS DIETER
IPC: A61J3/10 , A61K9/20 , A61K9/24 , A61K9/28 , A61K31/07 , A61K31/167 , A61K31/192 , A61K31/277 , A61K31/355 , A61K31/375 , A61K31/401 , A61K31/4422 , A61K31/52 , A61K31/522 , A61K31/60
Abstract: PCT No. PCT/EP96/04601 Sec. 371 Date Apr. 15, 1998 Sec. 102(e) Date Apr. 15, 1998 PCT Filed Oct. 23, 1996 PCT Pub. No. WO97/15293 PCT Pub. Date May 1, 1997The present invention relates to a process for producing multilayer, solid drug forms for oral or rectal administration, which comprises coextrusion of at least two compositions which in each case comprise a thermoplastic, pharmacologically acceptable polymeric binder which is soluble or swellable in a physiological environment, and at least one of which contains a pharmaceutical active ingredient, and shaping the coextruded multilayer material to the required drug form.
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公开(公告)号：CZ9804202A3
公开(公告)日：1999-03-17
申请号：CZ420298
申请日：1997-06-05
Applicant: BASF AG
Inventor： MERKLE HANS RUPERT , FRETSCHNER ERICH , HOFMANN JURGEN , JAGER KARL-FRIEDRICH , DIENER RALPH , HARTL AXEL PAUL , SCHONHERR MICHAEL
CPC classification number: C07C51/412 , C07C59/68
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Patent Agency Ranking5.发明专利
公开(公告)号：CA2232356C
公开(公告)日：2005-08-23
申请号：CA2232356
申请日：1996-10-23
Applicant: BASF AG
Inventor： ZETTLER HANS DIETER , HOFMANN JURGEN , ROSENBERG JOERG , HARTL AXEL PAUL , BREITENBACH JORG , SCHIESSL MICHAEL
IPC: A61J3/10 , A61K9/20 , A61K9/24 , A61K9/28 , A61K31/07 , A61K31/167 , A61K31/192 , A61K31/277 , A61K31/355 , A61K31/375 , A61K31/401 , A61K31/4422 , A61K31/52 , A61K31/522 , A61K31/60 , A61K9/02 , A61K31/19 , A61K31/275 , A61K31/40 , A61K31/455
Abstract: The invention concerns a method of producing multi-layer medicaments in soli d form for oral or rectal administration. At least two substances, which each comprise a thermoplastic, pharmacologically acceptable polymer binder which is soluble or can swell in a physiological environment, at least one of the substances comprising a pharmaceutical active substance, are coextruded and the coextruded multi-layer material is shaped to form the desired medicament.
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公开(公告)号：ES2175139T3
公开(公告)日：2002-11-16
申请号：ES96937214
申请日：1996-10-23
Applicant: BASF AG
Inventor： BREITENBACH JORG , HARTL AXEL PAUL , HOFMANN JURGEN , ROSENBERG JOERG , SCHIESSL MICHAEL , ZETTLER HANS DIETER
IPC: A61J3/10 , A61K9/20 , A61K9/24 , A61K9/28 , A61K31/07 , A61K31/167 , A61K31/192 , A61K31/277 , A61K31/355 , A61K31/375 , A61K31/401 , A61K31/4422 , A61K31/52 , A61K31/522 , A61K31/60
Abstract: PCT No. PCT/EP96/04601 Sec. 371 Date Apr. 15, 1998 Sec. 102(e) Date Apr. 15, 1998 PCT Filed Oct. 23, 1996 PCT Pub. No. WO97/15293 PCT Pub. Date May 1, 1997The present invention relates to a process for producing multilayer, solid drug forms for oral or rectal administration, which comprises coextrusion of at least two compositions which in each case comprise a thermoplastic, pharmacologically acceptable polymeric binder which is soluble or swellable in a physiological environment, and at least one of which contains a pharmaceutical active ingredient, and shaping the coextruded multilayer material to the required drug form.
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公开(公告)号：CZ420298A3
公开(公告)日：1999-03-17
申请号：CZ420298
申请日：1997-06-05
Applicant: BASF AG
Inventor： MERKLE HANS RUPERT , FRETSCHNER ERICH , HOFMANN JURGEN , JAGER KARL-FRIEDRICH , DIENER RALPH , HARTL AXEL PAUL , SCHONHERR MICHAEL
Abstract: A process for the production of alkaline metal salts and earth alkali metal salts of aryloxy-C1-C4-alkane carboxylic acids by reacting the basic aryloxy-C1-C4-alkane carboxylic acids with alkaline metal bases or earth alkali metal bases in the melt, by extruding a mixture of the aryloxy-C1-C4-alkane carboxylic acid and an at least stoichiometric quantity of an alkaline metal base or an earth alkali metal base, which are partially or completely converted in the reaction conditions into volatile substances. The invention also concerns the extrudates thus obtainable and the use of the extrudates which contain an aryloxy-C1-C4-alkane carboxylic acid with herbicidal action to combat undesired plant growth.
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公开(公告)号：IN182500B
公开(公告)日：1999-04-17
申请号：IN1824MA1996
申请日：1996-10-16
Applicant: BASF AG
Inventor： BREITENBACH JORG , HARTL AXEL PAUL , HOFMANN JURGEN , ROSENBERG JOERG , SCHIEBL MICHAEL , ZETTLER HANS DIETER
IPC: A61J3/10 , A61K9/20 , A61K9/24 , A61K9/28 , A61K31/07 , A61K31/167 , A61K31/192 , A61K31/277 , A61K31/355 , A61K31/375 , A61K31/401 , A61K31/4422 , A61K31/52 , A61K31/522 , A61K31/60 , A61K9/00
Abstract: PCT No. PCT/EP96/04601 Sec. 371 Date Apr. 15, 1998 Sec. 102(e) Date Apr. 15, 1998 PCT Filed Oct. 23, 1996 PCT Pub. No. WO97/15293 PCT Pub. Date May 1, 1997The present invention relates to a process for producing multilayer, solid drug forms for oral or rectal administration, which comprises coextrusion of at least two compositions which in each case comprise a thermoplastic, pharmacologically acceptable polymeric binder which is soluble or swellable in a physiological environment, and at least one of which contains a pharmaceutical active ingredient, and shaping the coextruded multilayer material to the required drug form.
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9.发明专利
公开(公告)号：AU7491296A
公开(公告)日：1997-05-15
申请号：AU7491296
申请日：1996-10-23
Applicant: BASF AG
Inventor： BREITENBACH JORG , HARTL AXEL PAUL , HOFMANN JURGEN , ROSENBERG JOERG , SCHIESSL MICHAEL , ZETTLER HANS DIETER
IPC: A61J3/10 , A61K9/20 , A61K9/24 , A61K9/28 , A61K31/07 , A61K31/167 , A61K31/192 , A61K31/277 , A61K31/355 , A61K31/375 , A61K31/401 , A61K31/4422 , A61K31/52 , A61K31/522 , A61K31/60
Abstract: PCT No. PCT/EP96/04601 Sec. 371 Date Apr. 15, 1998 Sec. 102(e) Date Apr. 15, 1998 PCT Filed Oct. 23, 1996 PCT Pub. No. WO97/15293 PCT Pub. Date May 1, 1997The present invention relates to a process for producing multilayer, solid drug forms for oral or rectal administration, which comprises coextrusion of at least two compositions which in each case comprise a thermoplastic, pharmacologically acceptable polymeric binder which is soluble or swellable in a physiological environment, and at least one of which contains a pharmaceutical active ingredient, and shaping the coextruded multilayer material to the required drug form.
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