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公开(公告)号：DE4420751A1
公开(公告)日：1995-12-21
申请号：DE4420751
申请日：1994-06-15
Applicant: BASF AG
Inventor： STAUDENMAIER HORST RALF DR , HAUER BERNHARD DR , BALKENHOHL FRIEDHELM DR , LADNER WOLFGANG DR , SCHNELL URSULA DR , PRESLER UWE DR
IPC: C12P17/10 , C12P41/00 , C12R1/01 , C12R1/38 , C07C201/16 , C07D227/087 , C07D207/267 , C07D203/00 , C07D205/08 , C07D211/76
Abstract: Prodn. of enantiomeric lactams of formula (I) comprises reacting a racemate (I) with a biocatalyst which reacts with one enantiomer and isolating the unreacted enantiomer from the mixt. obtd. R1, R2 = 1-4C alkyl, 2-4C alkenyl or aryl (all opt. substd.), H or (CH2)n-COOH; n = 0-3; x = 1-5. Pref. the biocatalyst is a microorganism, esp. from Pseudomonas or Rhodococcus.
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公开(公告)号：DK0687736T3
公开(公告)日：1997-07-21
申请号：DK95108695
申请日：1995-06-07
Applicant: BASF AG
Inventor： STAUDENMAIER HORST RALF DR , HAUER BERNHARD DR , BALKENHOHL FRIEDHELM DR , LADNER WOLFGANG DR , SCHNELL URSULA DR , PRESSLER UWE DR
Abstract: Prodn. of enantiomeric lactams of formula (I) comprises reacting a racemate (I) with a biocatalyst which reacts with one enantiomer and isolating the unreacted enantiomer from the mixt. obtd. R1, R2 = 1-4C alkyl, 2-4C alkenyl or aryl (all opt. substd.), H or (CH2)n-COOH; n = 0-3; x = 1-5. Pref. the biocatalyst is a microorganism, esp. from Pseudomonas or Rhodococcus.
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公开(公告)号：DE4325850A1
公开(公告)日：1995-04-27
申请号：DE4325850
申请日：1993-07-31
Applicant: BASF AG
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公开(公告)号：DE4329293A1
公开(公告)日：1995-03-02
申请号：DE4329293
申请日：1993-08-31
Applicant: BASF AG
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公开(公告)号：DE4220241A1
公开(公告)日：1993-12-23
申请号：DE4220241
申请日：1992-06-20
Applicant: BASF AG
Inventor： STAUDENMAIER HORST RALF DR , HAUER BERNHARD DR , LADNER WOLFGANG DR , MUELLER URSULA DR , PRESSLER UWE DR , MEYER JOACHIM DR
Abstract: The invention concerns a method for the preparation of 3-hydroxyphenylacetic acid by cultivating a microorganism of the species Rhizoctonia, Ceratobasidium or Pellicularia in the presence of a phenyl compound of general formula (I), in which X = COOR, CH2OH, CH2NH2 or (II) and R = methyl, ethyl, hydrogen, sodium, potassium or ammonium.
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Patent Agency Ranking
公开(公告)号：AT152774T
公开(公告)日：1997-05-15
申请号：AT95108695
申请日：1995-06-07
Applicant: BASF AG
Inventor： STAUDENMAIER HORST RALF DR , HAUER BERNHARD DR , BALKENHOHL FRIEDHELM DR , LADNER WOLFGANG DR , SCHNELL URSULA DR , PRESSLER UWE DR
Abstract: Prodn. of enantiomeric lactams of formula (I) comprises reacting a racemate (I) with a biocatalyst which reacts with one enantiomer and isolating the unreacted enantiomer from the mixt. obtd. R1, R2 = 1-4C alkyl, 2-4C alkenyl or aryl (all opt. substd.), H or (CH2)n-COOH; n = 0-3; x = 1-5. Pref. the biocatalyst is a microorganism, esp. from Pseudomonas or Rhodococcus.
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公开(公告)号：DE4332738A1
公开(公告)日：1995-03-30
申请号：DE4332738
申请日：1993-09-25
Applicant: BASF AG
Inventor： BALKENHOHL FRIEDHELM DR , HAUER BERNHARD DR , LANDNER WOLFGANG DR , PRESSLER UWE DR
IPC: C12P13/02 , C12P41/00 , C12R1/38 , C07C209/88 , C07B57/00
Abstract: PCT No. PCT/EP94/03102 Sec. 371 Date Mar. 11, 1996 Sec. 102(e) Date Mar. 11, 1996 PCT Filed Sep. 16, 1994 PCT Pub. No. WO95/08636 PCT Pub. Date Mar. 30, 1995A process for producing optically active primary and secondary amines from the corresponding racemates is characterised in that (a) a racemic amine is enantioselectively acylated in the presence of a hydrolase with an ester whose acid component bears a fluorine, nitrogen, oxygen or sulphur atom at the proximity of the carbonyl carbon atom; (b) the mixture of optically active amine and optically active acylated amine is separated so that an enantiomer of amine is produced; (c) if desired the other enantiomer of the amine is extracted from the acylated amine by amide cleavage.
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公开(公告)号：DE4232522A1
公开(公告)日：1994-03-31
申请号：DE4232522
申请日：1992-09-29
Applicant: BASF AG
Inventor： STAUDENMAIER HORST RALF DR , HAUER BERNHARD DR , LADNER WOLFGANG DR , PRESSLER UWE DR , MEYER JOACHIM DR
Abstract: The invention concerns a fermentative method of preparing 2-hydroxyphenylacetic acid from phenylacetic acid, plus microorganisms suitable for carrying out the method.
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公开(公告)号：DE4142943A1
公开(公告)日：1993-07-01
申请号：DE4142943
申请日：1991-12-24
Applicant: BASF AG
Inventor： LADNER WOLFGANG DR , STAUDENMAIER HORST RALF DR , HAUER BERNHARD DR , MUELLER URSULA DR , PRESSLER UWE DR , MEYER JOACHIM DR , SIEGEL HARDO DR
Abstract: Described is a method of hydroxylating, using microorganisms, compounds of the formula (I), in which A and R to R are as defined in the description.
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公开(公告)号：CZ20011382A3
公开(公告)日：2002-03-13
申请号：CZ20011382
申请日：1999-10-13
Applicant: BASF AG
Inventor： RESS-LOSCHKE MARION DR , FRIEDRICH THOMAS DR , HAUER BERNHARD DR , MATTES RALF PROF DR , ENGELS DIRK DR
IPC: C12N15/09 , C07H21/00 , C12N1/21 , C12N9/78 , C12N15/55 , C12P7/40 , C12P7/42 , C12P41/00 , C12R1/05 , C12N15/63
Abstract: The invention relates to nucleic acid sequences which code for a polypeptide having nitrilase activity, to nucleic acid constructs comprising the nucleic acid sequences, and to vectors comprising the nucleic acid sequences or the nucleic acid constructs. The invention further relates to amino acid sequences which are encoded by the nucleic acid sequences, and to microorganisms comprising the nucleic acid sequences, the nucleic acid constructs or vectors comprising the nucleic acid sequences or the nucleic acid constructs.The invention additionally relates to a process for preparing chiral carboxylic acids from the racemic nitriles.
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