公开(公告)号：GR3023791T3

公开(公告)日：1997-09-30

申请号：GR970401431

申请日：1997-06-18

Applicant: BASF AG

Inventor： STAUDENMAIER HORST RALF DR ,  HAUER BERNHARD DR ,  BALKENHOHL FRIEDHELM DR ,  LADNER WOLFGANG DR ,  SCHNELL URSULA DR ,  PRESSLER UWE DR

IPC: C12P17/10 ,  C12P41/00 ,  C12R1/01 ,  C12R1/38

Abstract: Prodn. of enantiomeric lactams of formula (I) comprises reacting a racemate (I) with a biocatalyst which reacts with one enantiomer and isolating the unreacted enantiomer from the mixt. obtd. R1, R2 = 1-4C alkyl, 2-4C alkenyl or aryl (all opt. substd.), H or (CH2)n-COOH; n = 0-3; x = 1-5. Pref. the biocatalyst is a microorganism, esp. from Pseudomonas or Rhodococcus.

公开(公告)号：ES2100759T3

公开(公告)日：1997-06-16

申请号：ES95108695

申请日：1995-06-07

Applicant: BASF AG

Inventor： STAUDENMAIER HORST RALF DR ,  HAUER BERNHARD DR ,  BALKENHOHL FRIEDHELM DR ,  LADNER WOLFGANG DR ,  SCHNELL URSULA DR ,  PRESSLER UWE DR

IPC: C12P17/10 ,  C12P41/00 ,  C12R1/01 ,  C12R1/38

Abstract: Prodn. of enantiomeric lactams of formula (I) comprises reacting a racemate (I) with a biocatalyst which reacts with one enantiomer and isolating the unreacted enantiomer from the mixt. obtd. R1, R2 = 1-4C alkyl, 2-4C alkenyl or aryl (all opt. substd.), H or (CH2)n-COOH; n = 0-3; x = 1-5. Pref. the biocatalyst is a microorganism, esp. from Pseudomonas or Rhodococcus.

公开(公告)号：DE59500222D1

公开(公告)日：1997-06-12

申请号：DE59500222

申请日：1995-06-07

Applicant: BASF AG

Inventor： STAUDENMAIER HORST RALF DR ,  HAUER BERNHARD DR ,  BALKENHOHL FRIEDHELM DR ,  LADNER WOLFGANG DR ,  SCHNELL URSULA DR ,  PRESSLER UWE DR

IPC: C12P17/10 ,  C12P41/00 ,  C12R1/01 ,  C12R1/38

Abstract: Prodn. of enantiomeric lactams of formula (I) comprises reacting a racemate (I) with a biocatalyst which reacts with one enantiomer and isolating the unreacted enantiomer from the mixt. obtd. R1, R2 = 1-4C alkyl, 2-4C alkenyl or aryl (all opt. substd.), H or (CH2)n-COOH; n = 0-3; x = 1-5. Pref. the biocatalyst is a microorganism, esp. from Pseudomonas or Rhodococcus.

公开(公告)号：DE4344211A1

公开(公告)日：1995-06-29

申请号：DE4344211

申请日：1993-12-23

Applicant: BASF AG

Inventor： BAKLENHOHL FRIEDHELM DR ,  HAUER BERNHARD DR ,  LADNER WOLFGANG DR ,  PRESSLER UWE DR ,  RETTENMAIER HANSJOERG DR ,  ADAM GEO DR

IPC: C12N9/20 ,  C12N9/96 ,  C07B41/12 ,  C07C53/126 ,  C07C69/22 ,  C12N9/14 ,  C12N9/18

公开(公告)号：DK0687736T3

公开(公告)日：1997-07-21

申请号：DK95108695

申请日：1995-06-07

Applicant: BASF AG

Inventor： STAUDENMAIER HORST RALF DR ,  HAUER BERNHARD DR ,  BALKENHOHL FRIEDHELM DR ,  LADNER WOLFGANG DR ,  SCHNELL URSULA DR ,  PRESSLER UWE DR

IPC: C12P17/10 ,  C12P41/00 ,  C12R1/01 ,  C12R1/38

Abstract: Prodn. of enantiomeric lactams of formula (I) comprises reacting a racemate (I) with a biocatalyst which reacts with one enantiomer and isolating the unreacted enantiomer from the mixt. obtd. R1, R2 = 1-4C alkyl, 2-4C alkenyl or aryl (all opt. substd.), H or (CH2)n-COOH; n = 0-3; x = 1-5. Pref. the biocatalyst is a microorganism, esp. from Pseudomonas or Rhodococcus.

公开(公告)号：DE4325850A1

公开(公告)日：1995-04-27

申请号：DE4325850

申请日：1993-07-31

Applicant: BASF AG

Inventor： PRESSLER UWE DR ,  BALKENHOHL FRIEDHELM DR ,  HAUER BERNHARD DR ,  LADNER WOLFGANG DR ,  MUELLER URSULA DR ,  STAUDENMAIER HORST RALF DR

IPC: C07D319/06 ,  C12P7/04 ,  C12P7/24 ,  C12P7/40 ,  C12P17/00 ,  C07C59/60 ,  C07B41/00 ,  C07C51/215 ,  C12N1/20 ,  C12P7/02 ,  C12P7/22

公开(公告)号：DE4329293A1

公开(公告)日：1995-03-02

申请号：DE4329293

申请日：1993-08-31

Applicant: BASF AG

Inventor： BALKENHOHL FRIEDHELM DR ,  HAUER BERNHARD DR ,  LADNER WOLFGANG DR ,  SCHNELL URSULA DR ,  PRESSLER UWE DR ,  STAUDENMAIER HORST RALF DR

IPC: C12P7/02 ,  C07C27/02 ,  C07C29/09 ,  C07C29/88 ,  C07C33/26 ,  C07C67/46 ,  C12P7/62 ,  C12P41/00 ,  C12R1/38 ,  C07B57/00 ,  C07C27/26 ,  C07C29/74 ,  C07C67/48 ,  C07D305/10

公开(公告)号：DE4220241A1

公开(公告)日：1993-12-23

申请号：DE4220241

申请日：1992-06-20

Applicant: BASF AG

Inventor： STAUDENMAIER HORST RALF DR ,  HAUER BERNHARD DR ,  LADNER WOLFGANG DR ,  MUELLER URSULA DR ,  PRESSLER UWE DR ,  MEYER JOACHIM DR

IPC: C12P7/42 ,  C12P7/54 ,  C12R1/645 ,  C07C59/52

Abstract: The invention concerns a method for the preparation of 3-hydroxyphenylacetic acid by cultivating a microorganism of the species Rhizoctonia, Ceratobasidium or Pellicularia in the presence of a phenyl compound of general formula (I), in which X = COOR, CH2OH, CH2NH2 or (II) and R = methyl, ethyl, hydrogen, sodium, potassium or ammonium.

公开(公告)号：AT152774T

公开(公告)日：1997-05-15

申请号：AT95108695

申请日：1995-06-07

Applicant: BASF AG

Inventor： STAUDENMAIER HORST RALF DR ,  HAUER BERNHARD DR ,  BALKENHOHL FRIEDHELM DR ,  LADNER WOLFGANG DR ,  SCHNELL URSULA DR ,  PRESSLER UWE DR

IPC: C12P17/10 ,  C12P41/00 ,  C12R1/01 ,  C12R1/38

Abstract: Prodn. of enantiomeric lactams of formula (I) comprises reacting a racemate (I) with a biocatalyst which reacts with one enantiomer and isolating the unreacted enantiomer from the mixt. obtd. R1, R2 = 1-4C alkyl, 2-4C alkenyl or aryl (all opt. substd.), H or (CH2)n-COOH; n = 0-3; x = 1-5. Pref. the biocatalyst is a microorganism, esp. from Pseudomonas or Rhodococcus.

公开(公告)号：DE4332738A1

公开(公告)日：1995-03-30

申请号：DE4332738

申请日：1993-09-25

Applicant: BASF AG

Inventor： BALKENHOHL FRIEDHELM DR ,  HAUER BERNHARD DR ,  LANDNER WOLFGANG DR ,  PRESSLER UWE DR

IPC: C12P13/02 ,  C12P41/00 ,  C12R1/38 ,  C07C209/88 ,  C07B57/00

Abstract: PCT No. PCT/EP94/03102 Sec. 371 Date Mar. 11, 1996 Sec. 102(e) Date Mar. 11, 1996 PCT Filed Sep. 16, 1994 PCT Pub. No. WO95/08636 PCT Pub. Date Mar. 30, 1995A process for producing optically active primary and secondary amines from the corresponding racemates is characterised in that (a) a racemic amine is enantioselectively acylated in the presence of a hydrolase with an ester whose acid component bears a fluorine, nitrogen, oxygen or sulphur atom at the proximity of the carbonyl carbon atom; (b) the mixture of optically active amine and optically active acylated amine is separated so that an enantiomer of amine is produced; (c) if desired the other enantiomer of the amine is extracted from the acylated amine by amide cleavage.