公开(公告)号：DE3038504A1

公开(公告)日：1982-06-03

申请号：DE3038504

申请日：1980-10-11

Applicant: BASF AG

Inventor： HICKMANN ECKHARD DIPL CHEM DR ,  OESER HEINZ-GUENTER DIPL CHEM

IPC: A61K31/47 ,  A61P33/02 ,  C07D213/57 ,  C07D215/12 ,  C07D215/18 ,  C07D401/06 ,  C07D401/14 ,  C07F9/58 ,  C07F9/60 ,  C07F9/62 ,  C07F9/6558

Abstract: Quinol-4-ylmethane derivatives of the formula I I where R1 is hydrogen or chlorine, R2 is trifluoromethyl or chlorine, R3 is a nitrogen-containing, cyclic-unsaturated or acyclic-saturated radical of not more than 6 carbon atoms, R4 is hydrogen or an anion-stabilizing group and R5 is hydrogen, an anion center or an acetal radical of not more than 8 carbon atoms, their preparation and their use for the preparation of quinol-4-ylmethane derivatives.

公开(公告)号：DE2747956A1

公开(公告)日：1979-05-03

申请号：DE2747956

申请日：1977-10-26

Applicant: BASF AG

Inventor： SCHUSTER LUDWIG DIPL CHEM DR ,  HICKMANN ECKHARD DIPL CHEM DR ,  HALBRITTER KLAUS DIPL CHEM DR

IPC: C07C37/055 ,  C07C37/76 ,  C07C39/14 ,  C07C37/00

Abstract: Process for the manufacture of alpha -naphthol by hydrolyzing alpha -naphthyl esters of aliphatic carboxylic acids in a distillation column by means of steam in counter-current at a particular temperature, and in a certain ratio, in the presence of naphtholsulfonic acids and/or sulfonic acids of naphthyl esters. The alpha -naphthol obtainable by the process of the invention is a valuable starting material for the manufacture of dyes, drugs and insecticides, e.g. alpha -naphthyl N-methylcarbamate.

公开(公告)号：DE2911246A1

公开(公告)日：1980-10-02

申请号：DE2911246

申请日：1979-03-22

Applicant: BASF AG

Inventor： LINHART FRIEDRICH DIPL CHEM DR ,  GIRGENSOHN BJOERN DIPL CHEM DR ,  REISSENWEBER GERNOT DIPL CHEM ,  HICKMANN ECKHARD DIPL CHEM DR

IPC: C07C83/02

Abstract: O,N-Disubstituted hydroxylamines are prepared by reacting O-substituted ketoximes with hydrogen in the presence of a platinum catalyst at from 35 to 50 bar, in a medium containing a mineral acid. The O,N-disubstituted hydroxylamines I obtained by the process of the invention are valuable starting materials for the preparation of dyes, crop protection agents and drugs.

公开(公告)号：DE2734207A1

公开(公告)日：1979-02-08

申请号：DE2734207

申请日：1977-07-29

Applicant: BASF AG

Inventor： EBERHARD PETER DIPL CHEM DR ,  HICKMANN ECKHARD DIPL CHEM DR

IPC: C07C59/84 ,  C07C69/95 ,  C07C65/20

Abstract: Prodn. of alpha-ketocarboxylic acid derivs. of formula R1COR2 (R1 is opt. 1-30C aryl or (cyclo)alkyl, R2 is carboxylic acid deriv. gp.) (I) comprises oxidn. of corresp. hydroxy cpds (II) with Cl2 or Br2 at 180 degrees C. The solvent is pref. a halogenated hydrocarbon, specif. chlorobenzene and reaction is opt. in presence of light and/or a radical former. Acid derivs. used are esters, nitriles amides or halides, esp. 1-10C alkyl esters. (I) are intermediates for plant-protection agents and also useful as photoinitiators. The method is esp. used for arylglyoxylic acid esters. Good yields are achieved (no significant replacement of OH by halogen) without the need for expensive or polluting oxidising agents.

公开(公告)号：DE2940443A1

公开(公告)日：1981-04-16

申请号：DE2940443

申请日：1979-10-05

Applicant: BASF AG

Inventor： HICKMANN ECKHARD DIPL CHEM DR ,  OESER HEINZ-GUENTER DIPL CHEM ,  MOEBIUS LEANDER DIPL CHEM DR

IPC: C07D401/06 ,  A61K31/47 ,  C07D209/38 ,  C07D211/22 ,  C07D215/14 ,  C07D215/50

Abstract: The present invention relates to a simplified process, which avoids organo-lithium intermediates, for the preparation of erythro- alpha -piperid-2-yl-2,8-bis-(trifluoromethyl)-quinolin-4-yl-methanol, wherein 2,8-bis-(trifluoromethyl)-quinoline-4-carboxylic acid or a salt thereof is reacted with a pyrid-2-yl-magnesium halide to give pyrid-2-yl-2,8-bis-(trifluoromethyl)-quinolin-4-yl ketone in the manner of a Grignard reaction, and this product is hydrogenated, in a conventional manner, to give erythro- alpha -piperid-2-yl-2,8-bis-(trifluoromethyl)-quinolin-4-yl-methanol.

公开(公告)号：DE2538463A1

公开(公告)日：1977-03-10

申请号：DE2538463

申请日：1975-08-29

Applicant: BASF AG

Inventor： DOCKNER TONI DIPL CHEM DR ,  VOGEL LUDWIG DIPL ING ,  AUER EBERHARD DIPL ING ,  KRUG HERBERT ,  HICKMANN ECKHARD DIPL CHEM DR

IPC: B01J23/22 ,  B01J27/198 ,  C01B7/00 ,  C01B7/01 ,  C01B7/09 ,  C01B7/13 ,  C01B7/19 ,  C01B7/20 ,  C02F1/72 ,  C02F11/06 ,  F23G5/30 ,  F23G7/00

Abstract: Wastes from chemical processes contg. halogens and/or hydrogen halides and elemental carbon and/or a heavy organic residue and opt. water are reacted with oxygen or an O2-contg. gas at 300-700 degrees C in the presence of a catalyst system comprising V2O5 and an oxygen-contg. cpd. of P(V) on an inorganic carrier (having a specific surface area of 250-600 m2/g). The halogens and/or the hydrogen halides are sepd. from the gaseous reaction prods. by condensation or absorption in water. CO2 is released to the atmos. Complete combustion of carbon is achieved. The economy of the process is good because the fuel consumption is less than in the known processes.