Imidazole derivs. prodn. - by reacting 1,2-di:amine with carboxylic acid or dehydrogenating imidazoline in presence of zinc oxide

    公开(公告)号:DE2733466A1

    公开(公告)日:1979-02-22

    申请号:DE2733466

    申请日:1977-07-25

    Applicant: BASF AG

    Abstract: Prodn. of imidazoles of formula (I) comprises (a) reacting 1,2-diamines of formula (II) with carboxylic acids of formula (III) or (b) dehydrogenating 2-imidazolines of formula (IV), in either case by heating at 300-600 degrees C in the presence of zinc oxide or a mixt. of zinc oxide and aluminium oxide as catalyst: (R1 - R4 = H or an aliphatic, araliphatic, cycloaliphatic or aromatic residue). (I) are intermediates for dyes, plant protection agents, textile aids, polyurethane and epoxy resin catalysts, surfactants and pharmaceuticals (e.g. nitroimidazoles). They can also be used as catalysts for polymerisations and aldol condensations. (I) is obtd. in good yields and purity. The catalysts used are cheap and easily regenerated, and are not significantly poisoned after prolonged use.

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