Means and methods for preventing and/or treating caries

    公开(公告)号:AU2005281796C1

    公开(公告)日:2014-01-23

    申请号:AU2005281796

    申请日:2005-09-09

    Applicant: BASF AG

    Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase; (b) mixing said microorganism with Streptococcus mutans which has been grown to stationary phase; (c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and Streptococcus mutans and (d) detecting aggregates by the occurrence of a pellet. Another aspect of the present invention is an analog or fragment of said microorganism which is thermally inactivated or lyophilized, wherein said analog or fragment retains the capability of specifically binding to Streptococcus mutans. In addition, the present invention encompasses compositions and additives for food, feed or drinks comprising the microorganism belonging to the group of lactic acid bacteria which specifically bind to Streptococcus mutans or an analog or fragment thereof. Moreover, uses of said microorganism or said analog or fragment thereof for the preparation of an anticariogenic or pharmaceutical composition or anticariogenic food or feedstuff as well as methods for producing said compositions or food or feedstuff are provided by the present invention.

    BALANCED CARE PRODUCT CUSTOMIZATION

    公开(公告)号:CA2551771A1

    公开(公告)日:2005-07-28

    申请号:CA2551771

    申请日:2005-01-17

    Applicant: BASF AG

    Abstract: A method and system for formulating a custom product for an individual includes obtaining subjective and objective inputs from an individual in nee d of a custom prepared composition for changing or improving one or more of th e individual's conditions. Objective data may be collected by analyzing one or more samples taken from the individual. Subjective data may include data provided in response to a questionnaire by the individual. The objective and subjective inputs are compared against an empirically derived database which links certain affects to variables associated with the subjective and objective inputs. The formulation for the custom product may be derived by adapting the basic formula based on the objective and subjective inputs according to at least one adaptation criterion.

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