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公开(公告)号:DK346789D0
公开(公告)日:1989-07-13
申请号:DK346789
申请日:1989-07-13
Applicant: BASF AG
Inventor: MOELLER ACHIM , EMLING FRANZ , KURFUERST MANFRED , MEYER THOMAS
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公开(公告)号:BG62068B2
公开(公告)日:1999-01-29
申请号:BG9860494
申请日:1994-02-28
Applicant: BASF AG
Inventor: KURFUERST MANFRED , RUEBSAMEN KLAUS , SCHMIED BERNHARD , KOERWER WOLFGANG , SCHWEDEN JUERGEN , HOEFFKEN HANS W
IPC: A61K38/55 , A61K38/00 , A61K38/58 , A61K47/48 , A61P7/02 , C07K14/815 , C07K17/08 , C12N15/09 , C12P21/02 , C12R1/19 , C08G65/32
Abstract: The invention relates to new hirudinmuteins and theirpolyalkylenglycol conjugates with the formula[Z-(CH2)n-[O-CH2)n]m-W-]p Hirand to a method for their preparation. The compounds are suitablefor the prevention and treatment of carbiovascular diseases.16 claims
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公开(公告)号:ES2084149T3
公开(公告)日:1996-05-01
申请号:ES91900751
申请日:1990-11-22
Applicant: BASF AG
Inventor: KURFUERST MANFRED , RUEBSAMEN KLAUS , SCHMIED BERNHARD , KOERWER WOLFGANG , SCHWEDEN JURGEN , HOEFFKEN HANS WOLFGANG
IPC: A61K38/55 , A61K38/00 , A61K38/58 , A61K47/48 , A61P7/02 , C07K14/815 , C07K17/08 , C12N15/09 , C12P21/02 , C12R1/19
Abstract: PCT No. PCT/EP90/01998 Sec. 371 Date May 29, 1992 Sec. 102(e) Date May 29, 1992 PCT Filed Nov. 22, 1990 PCT Pub. No. WO91/08229 PCT Pub. Date Jun. 13, 1991Hirudin/polyalkylene glycol derivatives of the formula[A-(CH2)n-[O-(CH2)nlm-B-]p Hir [sic]I and hirudin muteins and the preparation thereof are described. The compounds are suitable for controlling diseases.
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公开(公告)号:DK587588D0
公开(公告)日:1988-10-21
申请号:DK587588
申请日:1988-10-21
Applicant: BASF AG
Inventor: KOERWER WOLFGANG , KURFUERST MANFRED , BALDINGER VERENA , DOERPER THOMAS
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公开(公告)号:ZA895325B
公开(公告)日:1991-04-24
申请号:ZA895325
申请日:1989-07-13
Applicant: BASF AG
Inventor: MOELLER ACHIM , ACHIM MOELLER , EMLING FRANZ , FRANZ EMLING , KURFUERST MANFRED , MANFRED KURFUERST , MEYER THOMAS , THOMAS MEYER
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公开(公告)号:ZA8905325B
公开(公告)日:1991-04-24
申请号:ZA8905325
申请日:1989-07-13
Applicant: BASF AG
Inventor: MOELLER ACHIM , ACHIM MOELLER , EMLING FRANZ , FRANZ EMLING , KURFUERST MANFRED , MANFRED KURFUERST , MEYER THOMAS , THOMAS MEYER
IPC: C12P21/06 , A61K39/395 , A61P7/00 , A61P9/00 , A61P17/00 , A61P29/00 , A61P37/00 , A61P37/08 , C07K1/22 , C07K16/00 , C07K16/24 , C12P21/08 , C07D , A61K
CPC classification number: C07K16/241
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公开(公告)号:FI893428A0
公开(公告)日:1989-07-14
申请号:FI893428
申请日:1989-07-14
Applicant: BASF AG
Inventor: MOELLER ACHIM , EMLING FRANZ , KURFUERST MANFRED , MEYER THOMAS
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公开(公告)号:LV5809A4
公开(公告)日:1997-02-20
申请号:LV960306
申请日:1996-07-22
Applicant: BASF AG
Inventor: KURFUERST MANFRED , RUEBSAMEN KLAUS , SCHMIED BERNHARD , KOERWER WOLFGANG , SCHWEDEN JUERGEN , HOEFFKEN HANS W
IPC: A61K38/58 , A61K47/48 , C07K14/815 , C07K17/08
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公开(公告)号:DE59010205D1
公开(公告)日:1996-04-18
申请号:DE59010205
申请日:1990-11-22
Applicant: BASF AG
Inventor: KURFUERST MANFRED , RUEBSAMEN KLAUS , SCHMIED BERNHARD , KOERWER WOLFGANG , SCHWEDEN JUERGEN , HOEFFKEN HANS
IPC: A61K38/55 , A61K38/00 , A61K38/58 , A61K47/48 , A61P7/02 , C07K14/815 , C07K17/08 , C12N15/09 , C12P21/02 , C12R1/19
Abstract: PCT No. PCT/EP90/01998 Sec. 371 Date May 29, 1992 Sec. 102(e) Date May 29, 1992 PCT Filed Nov. 22, 1990 PCT Pub. No. WO91/08229 PCT Pub. Date Jun. 13, 1991Hirudin/polyalkylene glycol derivatives of the formula[A-(CH2)n-[O-(CH2)nlm-B-]p Hir [sic]I and hirudin muteins and the preparation thereof are described. The compounds are suitable for controlling diseases.
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公开(公告)号:CA2067224A1
公开(公告)日:1991-06-02
申请号:CA2067224
申请日:1990-11-22
Applicant: BASF AG
Inventor: KURFUERST MANFRED , RUEBSAMEN KLAUS , SCHMIED BERNHARD , KOERWER WOLFGANG , SCHWEDEN JUERGEN , HOEFFKEN HANS W
IPC: A61K38/55 , A61K38/00 , A61K38/58 , A61K47/48 , A61P7/02 , C07K14/815 , C07K17/08 , C12N15/09 , C12P21/02 , C12R1/19 , C07K17/06
Abstract: Hirudin/polyalkylene glycol derivatives of the formula (A-(CH2)n-[O-(CH2)n]m-B-]p Hir [sic] I and hirudin muteins and the preparation thereof are described. The compounds are suitable for controlling diseases.
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