公开(公告)号：NO20041850A

公开(公告)日：2004-05-05

申请号：NO20041850

申请日：2004-05-05

Applicant: BASF AG

Inventor： MUELLER BERND WILLI WERNER ,  EINIG HEINZ ,  RASENACK NORBERT ,  FRIESE KAT

IPC: A61K9/20 ,  A61K9/14 ,  A61K9/16 ,  A61K9/26 ,  A61K31/192 ,  A61P29/00 ,  C07C51/43 ,  C07C51/50 ,  C07C57/30 ,  C07C59/64

CPC classification number: A61K31/192 ,  A61K9/145 ,  A61K9/146 ,  A61K9/1688

公开(公告)号：DE10153934A1

公开(公告)日：2003-05-22

申请号：DE10153934

申请日：2001-11-06

Applicant: BASF AG

Inventor： EINIG HEINZ ,  MUELLER BERND W ,  RASENACK NORBERT

IPC: A61K9/20 ,  A61K9/14 ,  A61K9/16 ,  A61K9/26 ,  A61K31/192 ,  A61P29/00 ,  C07C51/43 ,  C07C51/50 ,  C07C57/30 ,  C07C59/64 ,  C07C51/41 ,  C07B63/00 ,  C30B28/04

Abstract: The invention relates to a method for the formation of ibuprofen crystals, characterised in that the solidification occurs after crystallisation by displacement, crystallisation by cooling, crystallisation by evaporation or a combination thereof in the presence of one or several additives and the use of the ibuprofen produced as above for pharmaceutical formulations.

公开(公告)号：BR0213878A

公开(公告)日：2004-08-31

申请号：BR0213878

申请日：2002-10-25

Applicant: BASF AG

Inventor： EINING HEINZ ,  LLER BERND W M ,  RASENACK NORBERT ,  FRIESE KATRIN ,  FRANKE DIRK

IPC: A61K9/20 ,  A61K9/14 ,  A61K9/16 ,  A61K9/26 ,  A61K31/192 ,  A61P29/00 ,  C07C51/43 ,  C07C51/50 ,  C07C57/30 ,  C07C59/64

Abstract: The present invention relates to a process for the formation of profen crystals, which comprises carrying out the formation of solids by displacement precipitation, cooling crystallization, evaporative crystallization or a combination thereof in the presence of one or more additives, and the use of the profens thus prepared for pharmaceutical formulations.

公开(公告)号：NO20041850L

公开(公告)日：2004-05-05

申请号：NO20041850

申请日：2004-05-05

Applicant: BASF AG

Inventor： MUELLER BERND WILLI WERNER ,  EINIG HEINZ ,  RASENACK NORBERT ,  FRIESE KAT

IPC: A61K9/20 ,  A61K9/14 ,  A61K9/16 ,  A61K9/26 ,  A61K31/192 ,  A61P29/00 ,  C07C51/43 ,  C07C51/50 ,  C07C57/30 ,  C07C59/64

Abstract: The present invention relates to a process for the formation of profen crystals, which comprises carrying out the formation of solids by displacement precipitation, cooling crystallization, evaporative crystallization or a combination thereof in the presence of one or more additives, and the use of the profens thus prepared for pharmaceutical formulations.

公开(公告)号：CA2464756A1

公开(公告)日：2003-05-15

申请号：CA2464756

申请日：2002-10-25

Applicant: BASF AG

Inventor： MULLER BERND W ,  FRIESE KATRIN ,  RASENACK NORBERT ,  EINIG HEINZ ,  FRANKE DIRK

IPC: A61K9/20 ,  A61K9/14 ,  A61K9/16 ,  A61K9/26 ,  A61K31/192 ,  A61P29/00 ,  C07C51/43 ,  C07C51/50 ,  C07C57/30 ,  C07C59/64

Abstract: The invention relates to a method for the formation of ibuprofen crystals, characterised in that the solidification occurs after crystallisation by displacement, crystallisation by cooling, crystallisation by evaporation or a combination thereof in the presence of one or several additives and the use of the ibuprofen produced as above for pharmaceutical formulations.

公开(公告)号：HU0402006A2

公开(公告)日：2005-01-28

申请号：HU0402006

申请日：2002-10-25

Applicant: BASF AG

Inventor： EINIG HEINZ ,  MUELLER BERND W ,  RASENACK NORBERT ,  FRIESE KATRIN ,  FRANKE DIRK

IPC: A61K9/20 ,  A61K9/14 ,  A61K9/16 ,  A61K9/26 ,  A61K31/192 ,  A61P29/00 ,  C07C51/43 ,  C07C51/50 ,  C07C57/30 ,  C07C59/64

Abstract: The present invention relates to a process for the formation of profen crystals, which comprises carrying out the formation of solids by displacement precipitation, cooling crystallization, evaporative crystallization or a combination thereof in the presence of one or more additives, and the use of the profens thus prepared for pharmaceutical formulations.